JPS625154B2 - - Google Patents

Info

Publication number
JPS625154B2
JPS625154B2 JP52136788A JP13678877A JPS625154B2 JP S625154 B2 JPS625154 B2 JP S625154B2 JP 52136788 A JP52136788 A JP 52136788A JP 13678877 A JP13678877 A JP 13678877A JP S625154 B2 JPS625154 B2 JP S625154B2
Authority
JP
Japan
Prior art keywords
methyl
dimethyl
nonenyl
oxepane
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP52136788A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5365890A (en
Inventor
Kanoja Rametsushu
Wakutaa Maikeru
Chen Robaato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Pharmaceutical Corp
Original Assignee
Ortho Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharmaceutical Corp filed Critical Ortho Pharmaceutical Corp
Publication of JPS5365890A publication Critical patent/JPS5365890A/ja
Publication of JPS625154B2 publication Critical patent/JPS625154B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/04—Seven-membered rings not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP13678877A 1976-11-18 1977-11-16 Compounds and application thereof Granted JPS5365890A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/742,940 US4102895A (en) 1976-11-18 1976-11-18 Oxepanes

Publications (2)

Publication Number Publication Date
JPS5365890A JPS5365890A (en) 1978-06-12
JPS625154B2 true JPS625154B2 (ref) 1987-02-03

Family

ID=24986860

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13678877A Granted JPS5365890A (en) 1976-11-18 1977-11-16 Compounds and application thereof

Country Status (15)

Country Link
US (1) US4102895A (ref)
JP (1) JPS5365890A (ref)
AT (1) AT363478B (ref)
AU (1) AU516476B2 (ref)
CA (1) CA1113478A (ref)
CH (3) CH627469A5 (ref)
DE (1) DE2751396A1 (ref)
FR (1) FR2371443A1 (ref)
GB (1) GB1594100A (ref)
GR (1) GR63241B (ref)
IE (1) IE45915B1 (ref)
IL (1) IL53420A (ref)
NZ (1) NZ185641A (ref)
PH (1) PH13596A (ref)
ZA (1) ZA776879B (ref)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4182717A (en) * 1978-06-29 1980-01-08 Ortho Pharmaceutical Corp. Total synthesis of the utero-evacuant substance d,l-zoapatanol
US4177194A (en) * 1978-06-29 1979-12-04 Ortho Pharmaceutical Corporation Total synthesis of the utero-evacuant substance D,L-zoapatanol
US4256644A (en) * 1978-12-18 1981-03-17 Ortho Pharmaceutical Corporation Chemical intermediates in the preparation of oxepane compounds
US4215048A (en) * 1979-05-18 1980-07-29 Ortho Pharmaceutical Corporation Total synthesis of (1RS, 4SR, 5RS)-4-(4,8-dimethyl-5-hydroxy-7-nonenyl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid
US4237054A (en) * 1979-05-18 1980-12-02 Ortho Pharmaceutical Corporation Total synthesis of (1RS,4SR,5RS)-4-(4,8-dimethyl-5-hydroxy-7-nonenyl)-4-methyl-3,8-dioxabicyclo[3.2.1] octane-1-acetic acid
US4237055A (en) * 1979-06-18 1980-12-02 Ortho Pharmaceutical Corporation Synthesis of 1RS,4SR,5RS-4-(4,8-dimethyl-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid
US4322353A (en) * 1980-04-18 1982-03-30 Ortho Pharmaceutical Corporation Synthesis of dioxabicyclo(3.2.1)octanes and oxepanes
US4284565A (en) * 1980-05-02 1981-08-18 Ortho Pharmaceutical Corporation Total synthesis of 1RS,4SR,5RS-4-(4,8-dimethyl)-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid and related compounds
US4329288A (en) * 1980-05-02 1982-05-11 Ortho Pharmaceutical Corporation (1RS,4SR,5RS)-4-(5-Hydroxy-4,8-dimethyl-8-nonenyl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid
KR850000218B1 (ko) * 1980-07-31 1985-03-06 오오소오 화아마슈이티갈 코오포레이숀 디옥사비시클로[3.2.1]옥탄 유도체의 합성방법
US4277401A (en) * 1980-08-25 1981-07-07 Ortho Pharmaceutical Corporation Total synthesis of 1RS,4SR,5RS-4-(4,8-dimethyl)-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid
US4307019A (en) * 1980-08-25 1981-12-22 Ortho Pharmaceutical Corporation Total synthesis of 1RS,4SR,5RS,-4-(4,8-dimethyl-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid
US4322357A (en) * 1981-02-23 1982-03-30 Ortho Pharmaceutical Corporation Novel cycloheptanes
US4360467A (en) * 1981-02-23 1982-11-23 Ortho Pharmaceutical Corporation Process for preparing 8-oxabicyclo[3.2.1]-octane-1-acetic acids

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2515670C2 (de) * 1975-04-10 1985-07-25 Ortho Pharmaceutical Corp., Raritan, N.J. Verfahren zum Isolieren von Substanzen mit uteroevakuierender Wirkung aus der Zoapatl-Pflanze und diese Substanzen enthaltende Arzneimittel

Also Published As

Publication number Publication date
US4102895A (en) 1978-07-25
DE2751396A1 (de) 1978-05-24
IE45915L (en) 1978-05-18
CH627469A5 (fr) 1982-01-15
FR2371443A1 (fr) 1978-06-16
CH629792A5 (fr) 1982-05-14
NZ185641A (en) 1984-08-24
JPS5365890A (en) 1978-06-12
ATA824077A (de) 1981-01-15
AU3072977A (en) 1979-05-24
AU516476B2 (en) 1981-06-04
CA1113478A (en) 1981-12-01
CH629793A5 (fr) 1982-05-14
GB1594100A (en) 1981-07-30
ZA776879B (en) 1979-06-27
FR2371443B1 (ref) 1984-02-24
AT363478B (de) 1981-08-10
GR63241B (en) 1979-10-12
IE45915B1 (en) 1982-12-29
IL53420A0 (en) 1978-01-31
PH13596A (en) 1980-08-05
IL53420A (en) 1983-05-15

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