GR63241B - Chemical compounds having a substituted axamethane ring and preparation process thereof - Google Patents

Chemical compounds having a substituted axamethane ring and preparation process thereof

Info

Publication number
GR63241B
GR63241B GR54828A GR770154828A GR63241B GR 63241 B GR63241 B GR 63241B GR 54828 A GR54828 A GR 54828A GR 770154828 A GR770154828 A GR 770154828A GR 63241 B GR63241 B GR 63241B
Authority
GR
Greece
Prior art keywords
axamethane
substituted
ring
preparation process
chemical compounds
Prior art date
Application number
GR54828A
Other languages
English (en)
Inventor
R Chen
R Kanojia
M Wachter
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of GR63241B publication Critical patent/GR63241B/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D313/00Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02Seven-membered rings
    • C07D313/04Seven-membered rings not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08Bridged systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10Spiro-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Reproductive Health (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GR54828A 1976-11-18 1977-11-17 Chemical compounds having a substituted axamethane ring and preparation process thereof GR63241B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/742,940 US4102895A (en) 1976-11-18 1976-11-18 Oxepanes

Publications (1)

Publication Number Publication Date
GR63241B true GR63241B (en) 1979-10-12

Family

ID=24986860

Family Applications (1)

Application Number Title Priority Date Filing Date
GR54828A GR63241B (en) 1976-11-18 1977-11-17 Chemical compounds having a substituted axamethane ring and preparation process thereof

Country Status (15)

Country Link
US (1) US4102895A (el)
JP (1) JPS5365890A (el)
AT (1) AT363478B (el)
AU (1) AU516476B2 (el)
CA (1) CA1113478A (el)
CH (3) CH627469A5 (el)
DE (1) DE2751396A1 (el)
FR (1) FR2371443A1 (el)
GB (1) GB1594100A (el)
GR (1) GR63241B (el)
IE (1) IE45915B1 (el)
IL (1) IL53420A (el)
NZ (1) NZ185641A (el)
PH (1) PH13596A (el)
ZA (1) ZA776879B (el)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4177194A (en) * 1978-06-29 1979-12-04 Ortho Pharmaceutical Corporation Total synthesis of the utero-evacuant substance D,L-zoapatanol
US4182717A (en) * 1978-06-29 1980-01-08 Ortho Pharmaceutical Corp. Total synthesis of the utero-evacuant substance d,l-zoapatanol
US4256644A (en) * 1978-12-18 1981-03-17 Ortho Pharmaceutical Corporation Chemical intermediates in the preparation of oxepane compounds
US4215048A (en) * 1979-05-18 1980-07-29 Ortho Pharmaceutical Corporation Total synthesis of (1RS, 4SR, 5RS)-4-(4,8-dimethyl-5-hydroxy-7-nonenyl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid
US4237054A (en) * 1979-05-18 1980-12-02 Ortho Pharmaceutical Corporation Total synthesis of (1RS,4SR,5RS)-4-(4,8-dimethyl-5-hydroxy-7-nonenyl)-4-methyl-3,8-dioxabicyclo[3.2.1] octane-1-acetic acid
US4237055A (en) * 1979-06-18 1980-12-02 Ortho Pharmaceutical Corporation Synthesis of 1RS,4SR,5RS-4-(4,8-dimethyl-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid
US4322353A (en) * 1980-04-18 1982-03-30 Ortho Pharmaceutical Corporation Synthesis of dioxabicyclo(3.2.1)octanes and oxepanes
US4284565A (en) * 1980-05-02 1981-08-18 Ortho Pharmaceutical Corporation Total synthesis of 1RS,4SR,5RS-4-(4,8-dimethyl)-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid and related compounds
US4329288A (en) * 1980-05-02 1982-05-11 Ortho Pharmaceutical Corporation (1RS,4SR,5RS)-4-(5-Hydroxy-4,8-dimethyl-8-nonenyl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid
KR850000218B1 (ko) * 1980-07-31 1985-03-06 오오소오 화아마슈이티갈 코오포레이숀 디옥사비시클로[3.2.1]옥탄 유도체의 합성방법
US4307019A (en) * 1980-08-25 1981-12-22 Ortho Pharmaceutical Corporation Total synthesis of 1RS,4SR,5RS,-4-(4,8-dimethyl-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid
US4277401A (en) * 1980-08-25 1981-07-07 Ortho Pharmaceutical Corporation Total synthesis of 1RS,4SR,5RS-4-(4,8-dimethyl)-5-hydroxy-7-nonen-1-yl)-4-methyl-3,8-dioxabicyclo[3.2.1]octane-1-acetic acid
US4360467A (en) * 1981-02-23 1982-11-23 Ortho Pharmaceutical Corporation Process for preparing 8-oxabicyclo[3.2.1]-octane-1-acetic acids
US4322357A (en) * 1981-02-23 1982-03-30 Ortho Pharmaceutical Corporation Novel cycloheptanes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2515670C2 (de) * 1975-04-10 1985-07-25 Ortho Pharmaceutical Corp., Raritan, N.J. Verfahren zum Isolieren von Substanzen mit uteroevakuierender Wirkung aus der Zoapatl-Pflanze und diese Substanzen enthaltende Arzneimittel

Also Published As

Publication number Publication date
NZ185641A (en) 1984-08-24
CA1113478A (en) 1981-12-01
CH629792A5 (fr) 1982-05-14
AT363478B (de) 1981-08-10
AU3072977A (en) 1979-05-24
DE2751396A1 (de) 1978-05-24
US4102895A (en) 1978-07-25
IL53420A0 (en) 1978-01-31
JPS5365890A (en) 1978-06-12
IE45915B1 (en) 1982-12-29
FR2371443A1 (fr) 1978-06-16
ATA824077A (de) 1981-01-15
JPS625154B2 (el) 1987-02-03
CH629793A5 (fr) 1982-05-14
PH13596A (en) 1980-08-05
GB1594100A (en) 1981-07-30
IE45915L (en) 1978-05-18
FR2371443B1 (el) 1984-02-24
CH627469A5 (fr) 1982-01-15
AU516476B2 (en) 1981-06-04
ZA776879B (en) 1979-06-27
IL53420A (en) 1983-05-15

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