JPS62502842A - 置換２，３−ジヒドロ−６−ヒドロキシ−ピリミド〔２，１−ｆ〕プリン−４，８（１Ｈ，９Ｈ）−ジオン類 - Google Patents

置換２，３−ジヒドロ−６−ヒドロキシ−ピリミド〔２，１−ｆ〕プリン−４，８（１Ｈ，９Ｈ）−ジオン類

Info

Publication number
JPS62502842A
JPS62502842A JP61502835A JP50283586A JPS62502842A JP S62502842 A JPS62502842 A JP S62502842A JP 61502835 A JP61502835 A JP 61502835A JP 50283586 A JP50283586 A JP 50283586A JP S62502842 A JPS62502842 A JP S62502842A
Authority
JP
Japan
Prior art keywords
carbon atoms
purine
dihydro
phenyl
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP61502835A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0513953B2 (enExample
Inventor
ソロモン，ダニエル・モーデカイ
カミンスキー，ジェームズ・ジョセフ
コン，デーヴィッド・ジェフリー
Original Assignee
シェリング・コ−ポレ−ション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by シェリング・コ−ポレ−ション filed Critical シェリング・コ−ポレ−ション
Publication of JPS62502842A publication Critical patent/JPS62502842A/ja
Publication of JPH0513953B2 publication Critical patent/JPH0513953B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP61502835A 1985-05-13 1986-05-12 置換２，３−ジヒドロ−６−ヒドロキシ−ピリミド〔２，１−ｆ〕プリン−４，８（１Ｈ，９Ｈ）−ジオン類 Granted JPS62502842A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/732,994 US4666914A (en) 1985-05-13 1985-05-13 Anti-inflammatory and anti-allergic substituted-2,3-dihydro-6-(hydroxy)pyrimido[2,1-f]-purine-4,8(1H,9H)-diones
US732994 1985-05-13

Publications (2)

Publication Number Publication Date
JPS62502842A true JPS62502842A (ja) 1987-11-12
JPH0513953B2 JPH0513953B2 (enExample) 1993-02-23

Family

ID=24945768

Family Applications (1)

Application Number Title Priority Date Filing Date
JP61502835A Granted JPS62502842A (ja) 1985-05-13 1986-05-12 置換２，３−ジヒドロ−６−ヒドロキシ−ピリミド〔２，１−ｆ〕プリン−４，８（１Ｈ，９Ｈ）−ジオン類

Country Status (11)

Country Link
US (2) US4666914A (enExample)
EP (1) EP0221996B1 (enExample)
JP (1) JPS62502842A (enExample)
KR (1) KR900004834B1 (enExample)
AU (1) AU592088B2 (enExample)
CA (1) CA1283103C (enExample)
DE (1) DE3673759D1 (enExample)
DK (1) DK13487A (enExample)
FI (1) FI870079A0 (enExample)
HU (1) HU195221B (enExample)
WO (1) WO1986006724A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4847377A (en) * 1985-05-13 1989-07-11 Schering Corporation Substituted-2,3-dihydro-6-substituted-pyrimido[2,1-F]-purine-4,8(1H,9H)-diones
US4666914A (en) * 1985-05-13 1987-05-19 Schering Corporation Anti-inflammatory and anti-allergic substituted-2,3-dihydro-6-(hydroxy)pyrimido[2,1-f]-purine-4,8(1H,9H)-diones
GB8906792D0 (en) * 1989-03-23 1989-05-10 Beecham Wuelfing Gmbh & Co Kg Treatment and compounds
CN102452750B (zh) * 2010-10-15 2013-05-01 中国石油化工股份有限公司 炼油污水分类控制分级处理方法
WO2021243468A1 (en) * 2020-06-04 2021-12-09 London Pharmaceuticals And Research Corporation Rigid cannabidiol analogues as potent modulators of cannabinoid receptors and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862189A (en) * 1973-08-14 1975-01-21 Warner Lambert Co Aralkyl-substituted purines and pyrimidines as antianginal bronchodilator agents
US4457919A (en) * 1980-03-14 1984-07-03 Newport Pharmaceutical International, Inc. Method of imparting immunomodulating, antiviral or antitumor activity
DE3131365A1 (de) * 1981-08-07 1983-02-24 Henkel KGaA, 4000 Düsseldorf Neue diglycidyl-substituierte heterocyclische verbindungen, verfahren zu ihrer herstellung und ihre verwendung in arzneimittelzubereitungen mit cytostatischer wirksamkeit
US4569936A (en) * 1982-10-25 1986-02-11 Schering Corporation Anti-inflammatory substituted 9H-8-oxo-pyrimido[2,1-f]purine-2,4-diones
DE3370961D1 (en) * 1982-10-25 1987-05-21 Schering Corp Substituted 9h-8-oxo-pyrimido(2,1-f)purine-2,4-diones, process for their production and pharmaceutical compositions containing them
US4666914A (en) * 1985-05-13 1987-05-19 Schering Corporation Anti-inflammatory and anti-allergic substituted-2,3-dihydro-6-(hydroxy)pyrimido[2,1-f]-purine-4,8(1H,9H)-diones

Also Published As

Publication number Publication date
DK13487A (da) 1987-03-12
US4666914A (en) 1987-05-19
FI870079A7 (fi) 1987-01-09
KR870700624A (ko) 1987-12-30
EP0221996A1 (en) 1987-05-20
KR900004834B1 (ko) 1990-07-07
US4816458A (en) 1989-03-28
FI870079L (fi) 1987-01-09
CA1283103C (en) 1991-04-16
AU5816686A (en) 1986-12-04
DK13487D0 (da) 1987-01-12
FI870079A0 (fi) 1987-01-09
EP0221996B1 (en) 1990-08-29
HU195221B (en) 1988-04-28
DE3673759D1 (de) 1990-10-04
HUT41794A (en) 1987-05-28
AU592088B2 (en) 1990-01-04
WO1986006724A1 (en) 1986-11-20
JPH0513953B2 (enExample) 1993-02-23

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