DE3673759D1 - Substituierte 2,3-dihydro-6-hydroxy-pyrimido(2,1-f)purin-4,8(1h,9h)dione. - Google Patents

Substituierte 2,3-dihydro-6-hydroxy-pyrimido(2,1-f)purin-4,8(1h,9h)dione.

Info

Publication number
DE3673759D1
DE3673759D1 DE8686903777T DE3673759T DE3673759D1 DE 3673759 D1 DE3673759 D1 DE 3673759D1 DE 8686903777 T DE8686903777 T DE 8686903777T DE 3673759 T DE3673759 T DE 3673759T DE 3673759 D1 DE3673759 D1 DE 3673759D1
Authority
DE
Germany
Prior art keywords
pyrimido
purin
dione
dihydro
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686903777T
Other languages
German (de)
English (en)
Inventor
Daniel Mordecai Solomon
James Joseph Kaminski
David Jeffry Conn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DE3673759D1 publication Critical patent/DE3673759D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE8686903777T 1985-05-13 1986-05-12 Substituierte 2,3-dihydro-6-hydroxy-pyrimido(2,1-f)purin-4,8(1h,9h)dione. Expired - Lifetime DE3673759D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/732,994 US4666914A (en) 1985-05-13 1985-05-13 Anti-inflammatory and anti-allergic substituted-2,3-dihydro-6-(hydroxy)pyrimido[2,1-f]-purine-4,8(1H,9H)-diones
PCT/US1986/001004 WO1986006724A1 (en) 1985-05-13 1986-05-12 SUBSTITUTED 2,3-DIHYDRO-6-HYDROXY-PYRIMIDO AD2,1-f BD-PURINE-4,8(1H,9H)-DIONES

Publications (1)

Publication Number Publication Date
DE3673759D1 true DE3673759D1 (de) 1990-10-04

Family

ID=24945768

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686903777T Expired - Lifetime DE3673759D1 (de) 1985-05-13 1986-05-12 Substituierte 2,3-dihydro-6-hydroxy-pyrimido(2,1-f)purin-4,8(1h,9h)dione.

Country Status (11)

Country Link
US (2) US4666914A (enExample)
EP (1) EP0221996B1 (enExample)
JP (1) JPS62502842A (enExample)
KR (1) KR900004834B1 (enExample)
AU (1) AU592088B2 (enExample)
CA (1) CA1283103C (enExample)
DE (1) DE3673759D1 (enExample)
DK (1) DK13487A (enExample)
FI (1) FI870079A0 (enExample)
HU (1) HU195221B (enExample)
WO (1) WO1986006724A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4847377A (en) * 1985-05-13 1989-07-11 Schering Corporation Substituted-2,3-dihydro-6-substituted-pyrimido[2,1-F]-purine-4,8(1H,9H)-diones
US4666914A (en) * 1985-05-13 1987-05-19 Schering Corporation Anti-inflammatory and anti-allergic substituted-2,3-dihydro-6-(hydroxy)pyrimido[2,1-f]-purine-4,8(1H,9H)-diones
GB8906792D0 (en) * 1989-03-23 1989-05-10 Beecham Wuelfing Gmbh & Co Kg Treatment and compounds
CN102452750B (zh) * 2010-10-15 2013-05-01 中国石油化工股份有限公司 炼油污水分类控制分级处理方法
WO2021243468A1 (en) * 2020-06-04 2021-12-09 London Pharmaceuticals And Research Corporation Rigid cannabidiol analogues as potent modulators of cannabinoid receptors and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862189A (en) * 1973-08-14 1975-01-21 Warner Lambert Co Aralkyl-substituted purines and pyrimidines as antianginal bronchodilator agents
US4457919A (en) * 1980-03-14 1984-07-03 Newport Pharmaceutical International, Inc. Method of imparting immunomodulating, antiviral or antitumor activity
DE3131365A1 (de) * 1981-08-07 1983-02-24 Henkel KGaA, 4000 Düsseldorf Neue diglycidyl-substituierte heterocyclische verbindungen, verfahren zu ihrer herstellung und ihre verwendung in arzneimittelzubereitungen mit cytostatischer wirksamkeit
US4569936A (en) * 1982-10-25 1986-02-11 Schering Corporation Anti-inflammatory substituted 9H-8-oxo-pyrimido[2,1-f]purine-2,4-diones
DE3370961D1 (en) * 1982-10-25 1987-05-21 Schering Corp Substituted 9h-8-oxo-pyrimido(2,1-f)purine-2,4-diones, process for their production and pharmaceutical compositions containing them
US4666914A (en) * 1985-05-13 1987-05-19 Schering Corporation Anti-inflammatory and anti-allergic substituted-2,3-dihydro-6-(hydroxy)pyrimido[2,1-f]-purine-4,8(1H,9H)-diones

Also Published As

Publication number Publication date
DK13487A (da) 1987-03-12
US4666914A (en) 1987-05-19
JPS62502842A (ja) 1987-11-12
FI870079A7 (fi) 1987-01-09
KR870700624A (ko) 1987-12-30
EP0221996A1 (en) 1987-05-20
KR900004834B1 (ko) 1990-07-07
US4816458A (en) 1989-03-28
FI870079L (fi) 1987-01-09
CA1283103C (en) 1991-04-16
AU5816686A (en) 1986-12-04
DK13487D0 (da) 1987-01-12
FI870079A0 (fi) 1987-01-09
EP0221996B1 (en) 1990-08-29
HU195221B (en) 1988-04-28
HUT41794A (en) 1987-05-28
AU592088B2 (en) 1990-01-04
WO1986006724A1 (en) 1986-11-20
JPH0513953B2 (enExample) 1993-02-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee