JPS6241032B2 - - Google Patents
Info
- Publication number
- JPS6241032B2 JPS6241032B2 JP54092098A JP9209879A JPS6241032B2 JP S6241032 B2 JPS6241032 B2 JP S6241032B2 JP 54092098 A JP54092098 A JP 54092098A JP 9209879 A JP9209879 A JP 9209879A JP S6241032 B2 JPS6241032 B2 JP S6241032B2
- Authority
- JP
- Japan
- Prior art keywords
- signal
- patient
- output
- heart
- pacemaker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000000638 stimulation Effects 0.000 claims abstract description 84
- 230000000694 effects Effects 0.000 claims abstract description 32
- 230000004044 response Effects 0.000 claims abstract description 28
- 230000004936 stimulating effect Effects 0.000 claims abstract description 3
- 238000001514 detection method Methods 0.000 claims description 46
- 230000000747 cardiac effect Effects 0.000 claims description 45
- 102100026827 Protein associated with UVRAG as autophagy enhancer Human genes 0.000 claims description 30
- 101710102978 Protein associated with UVRAG as autophagy enhancer Proteins 0.000 claims description 30
- 238000002513 implantation Methods 0.000 claims description 18
- 238000003860 storage Methods 0.000 claims description 10
- 230000002401 inhibitory effect Effects 0.000 claims description 4
- 238000012545 processing Methods 0.000 claims description 2
- 230000007274 generation of a signal involved in cell-cell signaling Effects 0.000 claims 1
- 230000002861 ventricular Effects 0.000 abstract description 67
- 238000000034 method Methods 0.000 abstract description 31
- 230000008569 process Effects 0.000 abstract description 22
- 230000001746 atrial effect Effects 0.000 abstract description 19
- 235000014676 Phragmites communis Nutrition 0.000 abstract description 18
- 230000008859 change Effects 0.000 abstract description 16
- 206010003119 arrhythmia Diseases 0.000 abstract description 11
- 230000006793 arrhythmia Effects 0.000 abstract description 10
- 210000002837 heart atrium Anatomy 0.000 description 31
- 239000003990 capacitor Substances 0.000 description 27
- 210000001519 tissue Anatomy 0.000 description 27
- 230000036279 refractory period Effects 0.000 description 21
- 238000010586 diagram Methods 0.000 description 19
- 230000006870 function Effects 0.000 description 15
- 238000006243 chemical reaction Methods 0.000 description 14
- 230000003321 amplification Effects 0.000 description 8
- 238000003199 nucleic acid amplification method Methods 0.000 description 8
- 238000005516 engineering process Methods 0.000 description 7
- 230000010355 oscillation Effects 0.000 description 6
- 230000003247 decreasing effect Effects 0.000 description 5
- 230000005540 biological transmission Effects 0.000 description 4
- 230000007423 decrease Effects 0.000 description 4
- 230000007246 mechanism Effects 0.000 description 4
- 230000002829 reductive effect Effects 0.000 description 4
- 230000001360 synchronised effect Effects 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 230000003213 activating effect Effects 0.000 description 3
- 239000000872 buffer Substances 0.000 description 3
- 230000008602 contraction Effects 0.000 description 3
- 230000008878 coupling Effects 0.000 description 3
- 238000010168 coupling process Methods 0.000 description 3
- 238000005859 coupling reaction Methods 0.000 description 3
- 230000007547 defect Effects 0.000 description 3
- 230000008672 reprogramming Effects 0.000 description 3
- 238000012546 transfer Methods 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 238000003491 array Methods 0.000 description 2
- 238000010009 beating Methods 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 230000014509 gene expression Effects 0.000 description 2
- 210000005003 heart tissue Anatomy 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000028161 membrane depolarization Effects 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 206010013786 Dry skin Diseases 0.000 description 1
- 102000010292 Peptide Elongation Factor 1 Human genes 0.000 description 1
- 108010077524 Peptide Elongation Factor 1 Proteins 0.000 description 1
- 238000012084 abdominal surgery Methods 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000011128 cardiac conduction Effects 0.000 description 1
- 230000001756 cardiomyopathic effect Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000001010 compromised effect Effects 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000013016 damping Methods 0.000 description 1
- 238000013480 data collection Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000037336 dry skin Effects 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 230000007257 malfunction Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012806 monitoring device Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
- A61N1/37252—Details of algorithms or data aspects of communication system, e.g. handshaking, transmitting specific data or segmenting data
- A61N1/37264—Changing the program; Upgrading firmware
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
- A61N1/368—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/37—Monitoring; Protecting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/372—Arrangements in connection with the implantation of stimulators
- A61N1/37211—Means for communicating with stimulators
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92630378A | 1978-07-20 | 1978-07-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5521990A JPS5521990A (en) | 1980-02-16 |
| JPS6241032B2 true JPS6241032B2 (fr) | 1987-09-01 |
Family
ID=25453021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9209879A Granted JPS5521990A (en) | 1978-07-20 | 1979-07-19 | Pacemaker for bodily interior transplantation that have multiple mode and adaptability |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS5521990A (fr) |
| AU (2) | AU536053B2 (fr) |
| DE (2) | DE2929498A1 (fr) |
| FR (2) | FR2431296A1 (fr) |
| GB (2) | GB2026870B (fr) |
| IT (1) | IT1118131B (fr) |
| NL (1) | NL7905649A (fr) |
| SE (1) | SE445176B (fr) |
Families Citing this family (106)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7907462A (nl) * | 1978-10-30 | 1980-05-02 | Medtronic Inc | Hartgangmaker. |
| AU530108B2 (en) * | 1978-11-06 | 1983-06-30 | Medtronic, Inc. | Digital cardiac pacemaker |
| DE2944542A1 (de) * | 1978-11-06 | 1980-05-14 | Medtronic Inc | Vorrichtung zum programmieren von implantierten elektronischen geraeten, insbesondere schrittmachergeneratoren |
| US4273132A (en) * | 1978-11-06 | 1981-06-16 | Medtronic, Inc. | Digital cardiac pacemaker with threshold margin check |
| US4230120A (en) * | 1978-11-06 | 1980-10-28 | Medtronic, Inc. | Energy compensation means for digital cardiac pacemaker |
| US4295474A (en) * | 1979-10-02 | 1981-10-20 | The Johns Hopkins University | Recorder with patient alarm and service request systems suitable for use with automatic implantable defibrillator |
| US4278094A (en) * | 1979-10-10 | 1981-07-14 | Medtronic, Inc. | Pacemaker with pulse width adjustment circuitry |
| US4284082A (en) * | 1979-12-12 | 1981-08-18 | Medtronic B.V.Kerkrade | Ventricular synchronized atrial pacemaker and method of operation |
| US4388927A (en) * | 1979-12-13 | 1983-06-21 | American Hospital Supply Corporation | Programmable digital cardiac pacer |
| FR2471789A1 (fr) * | 1979-12-18 | 1981-06-26 | Cardiofrance Co | Stimulateur cardiaque implantable polyvalent et procede d'utilisation de ce stimulateur |
| AU547290B2 (en) * | 1980-04-07 | 1985-10-17 | Medtronic, Inc. | Artifact rejection by demand pacemakers |
| US4343311A (en) * | 1980-04-30 | 1982-08-10 | Medtronic, Inc. | Atrial refractory control for R-wave rejection in pacemakers |
| DE3038856A1 (de) * | 1980-10-10 | 1982-05-27 | Siemens AG, 1000 Berlin und 8000 München | Herzschrittmacher |
| AU541479B2 (en) * | 1980-10-14 | 1985-01-10 | Medtronic, Inc. | Heart pacemeker with separate a-v intervals for a trial synchronous and atrial-ventricular sequential pacing modes |
| FR2492262B1 (fr) * | 1980-10-16 | 1987-02-20 | Ela Medical Sa | Procede et dispositif de commande d'un appareil ou instrument notamment un stimulateur cardiaque implantable |
| DE3153780C2 (de) * | 1980-10-16 | 2003-04-03 | Ela Medical Sa | Verfahren zur Steuerung eines implantierbaren Herzschrittmachers |
| FR2492552A1 (fr) * | 1980-10-16 | 1982-04-23 | Ela Medical Sa | Dispositif de commande pour instrument medical implantable tel qu'un stimulateur cardiaque et stimulateur cardiaque comportant ce dispositif |
| US4485818A (en) * | 1980-11-14 | 1984-12-04 | Cordis Corporation | Multi-mode microprocessor-based programmable cardiac pacer |
| US4374382A (en) * | 1981-01-16 | 1983-02-15 | Medtronic, Inc. | Marker channel telemetry system for a medical device |
| US4363325A (en) * | 1981-01-19 | 1982-12-14 | Medtronic, Inc. | Mode adaptive pacer |
| DE3280360D1 (de) * | 1981-02-17 | 1991-10-31 | Medtronic Inc | Anzeiger des erschoepfungszustandes der speisequelle einpflanzbarer medizinischer geraete. |
| US4407288B1 (en) * | 1981-02-18 | 2000-09-19 | Mieczyslaw Mirowski | Implantable heart stimulator and stimulation method |
| EP0077808B1 (fr) * | 1981-05-04 | 1987-08-26 | BIOTRONIK Mess- und Therapiegeräte GmbH & Co Ingenieurbüro Berlin | Stimulateur cardiaque |
| WO1982003784A1 (fr) * | 1981-05-04 | 1982-11-11 | Nettelhorst Herwig | Stimulateur cardiaque |
| EP0077799B1 (fr) * | 1981-05-04 | 1987-11-11 | BIOTRONIK Mess- und Therapiegeräte GmbH & Co Ingenieurbüro Berlin | Stimulateur cardiaque |
| DE3278419D1 (en) * | 1981-05-04 | 1988-06-09 | Biotronik Mess & Therapieg | Cardiac pacemaker |
| EP0077809B1 (fr) * | 1981-05-04 | 1987-11-11 | BIOTRONIK Mess- und Therapiegeräte GmbH & Co Ingenieurbüro Berlin | Stimulateur cardiaque |
| DE3280048D1 (de) * | 1981-05-04 | 1990-01-11 | Biotronik Mess & Therapieg | Herzschrittmacher. |
| US4404972B1 (en) * | 1981-05-18 | 2000-07-11 | Intermedics Inc | Implantable device with microprocessor control |
| US4390022A (en) * | 1981-05-18 | 1983-06-28 | Intermedics, Inc. | Implantable device with microprocessor control |
| DE3127597A1 (de) * | 1981-07-13 | 1983-02-17 | Siemens AG, 1000 Berlin und 8000 München | Verfahren und herzschrittmacher zur bifokalen stimulierung des herzens |
| US4561444A (en) * | 1981-08-10 | 1985-12-31 | Cordis Corporation | Implantable cardiac pacer having dual frequency programming and bipolar/linipolar lead programmability |
| DE3175864D1 (en) * | 1981-10-26 | 1987-02-26 | Vitafin Nv | Pacemaker utilizing microprocessor dma for generating output pulse sequences |
| ATE25588T1 (de) * | 1981-10-26 | 1987-03-15 | Vitafin Nv | Programmierbarer herzschrittmacher. |
| DE3207006A1 (de) * | 1982-02-26 | 1983-09-08 | Siemens AG, 1000 Berlin und 8000 München | Av-sequenzieller herzschrittmacher |
| AU1573183A (en) * | 1982-06-18 | 1983-12-22 | Biostim Inc. | Biological electrical stimulators |
| US4562841A (en) * | 1982-08-05 | 1986-01-07 | Cardiac Pacemakers, Inc. | Programmable multi-mode cardiac pacemaker |
| FR2533432A1 (fr) * | 1982-09-23 | 1984-03-30 | Europ Propulsion | Procede et dispositif de detection de la reponse du coeur a une impulsion electrique de stimulation |
| US4467810A (en) * | 1982-09-30 | 1984-08-28 | Cordis Corporation | Multi-mode microprocessor-based programmable cardiac pacer |
| US4558702A (en) * | 1983-01-21 | 1985-12-17 | Cordis Corporation | Cardiac pacer having input/output circuit programmable for use with unipolar and bipolar pacer leads |
| US4665919A (en) * | 1983-03-14 | 1987-05-19 | Vitafin N.V. | Pacemaker with switchable circuits and method of operation of same |
| FR2544988B1 (fr) * | 1983-04-29 | 1986-10-10 | Ela Medical Sa | Stimulateur cardiaque auriculo-ventriculaire |
| US4549548A (en) * | 1983-09-14 | 1985-10-29 | Vitafin N.V. | Pacemaker system with automatic event-programmed switching between unipolar and bipolar operation |
| US4543963A (en) * | 1983-11-22 | 1985-10-01 | Gessman Lawrence J | Method and apparatus for differentiating antegrade from retrograde P-waves and for preventing pacemaker generated tachycardia |
| US4577634A (en) * | 1983-11-22 | 1986-03-25 | Gessman Lawrence J | Method and apparatus for alleviating paroxysmal atrail tachycardia |
| US4559947A (en) * | 1984-01-27 | 1985-12-24 | Renger Herman L | Cardiac tissue stimulator providing P-wave verification, telemetry, marker channels, and antitachycardia capabilities |
| EP0151689B1 (fr) * | 1984-02-07 | 1990-12-27 | SCHIAPPARELLI MEDTRONIC S.p.A. | Stimulateur cardiaque fonction du volume respiratoire par unité de temps |
| FR2561526A1 (fr) * | 1984-03-22 | 1985-09-27 | Chaptal Paul | Procede de stimulation cardiaque et stimulateur cardiaque pour mise en oeuvre du procede |
| US4585004A (en) * | 1984-06-01 | 1986-04-29 | Cardiac Control Systems, Inc. | Heart pacing and intracardiac electrogram monitoring system and associated method |
| US4587970A (en) * | 1985-01-22 | 1986-05-13 | Telectronics N.V. | Tachycardia reversion pacer |
| DE3688577D1 (de) * | 1985-09-17 | 1993-07-22 | Biotronik Mess & Therapieg | Herzschrittmacher. |
| DE3687388D1 (de) * | 1985-09-17 | 1993-02-11 | Biotronik Mess & Therapieg | Herzschrittmacher. |
| EP0216725B1 (fr) * | 1985-09-17 | 1993-12-01 | BIOTRONIK Mess- und Therapiegeräte GmbH & Co Ingenieurbüro Berlin | Stimulateur cardiaque |
| EP0215729B1 (fr) * | 1985-09-17 | 1992-12-02 | BIOTRONIK Mess- und Therapiegeräte GmbH & Co Ingenieurbüro Berlin | Stimulateur cardiaque |
| US4803987A (en) * | 1986-06-11 | 1989-02-14 | Intermedics, Inc. | Temperature responsive controller for cardiac pacer |
| DE3780374D1 (de) * | 1986-07-31 | 1992-08-20 | Irnich Werner | Frequenzadaptierender herzschrittmacher. |
| FR2604908B1 (fr) * | 1986-10-13 | 1990-06-22 | Saint Nicolas Cie Financiere | Procede de reglage d'un stimulateur cardiaque implantable en fonction de l'effort du patient porteur du stimulateur, stimulateur cardiaque implantable a parametres reglables et programmateur externe de commande d'un stimulateur cardiaque implantable reglable |
| DE3852893D1 (de) * | 1987-11-13 | 1995-03-09 | Biotronik Mess & Therapieg | Herzschrittmacher. |
| AU614118B2 (en) * | 1988-04-19 | 1991-08-22 | Pacesetter Ab | Configuration programming of an implantable pacemaker |
| US4899750A (en) * | 1988-04-19 | 1990-02-13 | Siemens-Pacesetter, Inc. | Lead impedance scanning system for pacemakers |
| EP0387363B1 (fr) * | 1989-03-13 | 1994-06-01 | Pacesetter AB | Stimulateur implantable dont l'intensité de stimulation d'un événement physiologique d'un être vivant est adaptée à son activité physique |
| US5031616A (en) * | 1989-12-07 | 1991-07-16 | Siemens-Pacesetter, Inc. | Implantable stimulation device having means for self-regulating curent drain usage at battery depletion |
| US5058581A (en) * | 1990-02-20 | 1991-10-22 | Siemens-Pacesetter, Inc. | Telemetry apparatus and method for implantable tissue stimulator |
| US5052389A (en) * | 1990-07-26 | 1991-10-01 | Cook Pacemaker Corporation | Low-power A/D converter for an implantable medical device and method of use |
| DE4339304B4 (de) * | 1993-11-18 | 2005-09-15 | Robert Bosch Gmbh | Schaltungsanordnung mit einem Übertragungsglied |
| US5725559A (en) * | 1996-05-16 | 1998-03-10 | Intermedics Inc. | Programmably upgradable implantable medical device |
| SE9602846D0 (sv) * | 1996-07-23 | 1996-07-23 | Pacesetter Ab | A stimulation device |
| DE19724053A1 (de) * | 1997-06-07 | 1998-12-10 | Biotronik Mess & Therapieg | Elektronische Speichervorrichtung, insbesondere zur Anwendung bei implantierbaren medizinischen Geräten |
| FR2772622B1 (fr) * | 1997-12-23 | 2000-03-31 | Ela Medical Sa | Dispositif medical implantable actif, notamment stimulateur cardiaque, defibrillateur et/ou cardioverteur, de type multisite configurable |
| US9050469B1 (en) | 2003-11-26 | 2015-06-09 | Flint Hills Scientific, Llc | Method and system for logging quantitative seizure information and assessing efficacy of therapy using cardiac signals |
| DE102004019391A1 (de) * | 2004-04-19 | 2005-11-03 | Endress + Hauser Gmbh + Co. Kg | Parametrierbares elektronisches Gerät |
| US9314633B2 (en) | 2008-01-25 | 2016-04-19 | Cyberonics, Inc. | Contingent cardio-protection for epilepsy patients |
| US8565867B2 (en) | 2005-01-28 | 2013-10-22 | Cyberonics, Inc. | Changeable electrode polarity stimulation by an implantable medical device |
| US8260426B2 (en) | 2008-01-25 | 2012-09-04 | Cyberonics, Inc. | Method, apparatus and system for bipolar charge utilization during stimulation by an implantable medical device |
| US8700163B2 (en) | 2005-03-04 | 2014-04-15 | Cyberonics, Inc. | Cranial nerve stimulation for treatment of substance addiction |
| US7711419B2 (en) | 2005-07-13 | 2010-05-04 | Cyberonics, Inc. | Neurostimulator with reduced size |
| US7840280B2 (en) | 2005-07-27 | 2010-11-23 | Cyberonics, Inc. | Cranial nerve stimulation to treat a vocal cord disorder |
| US7489561B2 (en) | 2005-10-24 | 2009-02-10 | Cyberonics, Inc. | Implantable medical device with reconfigurable non-volatile program |
| US7996079B2 (en) | 2006-01-24 | 2011-08-09 | Cyberonics, Inc. | Input response override for an implantable medical device |
| ES2573323T3 (es) | 2006-03-29 | 2016-06-07 | Dignity Health | Estímulo eléctrico de microrráfaga de nervios craneales para el tratamiento de afecciones médicas |
| US7962220B2 (en) | 2006-04-28 | 2011-06-14 | Cyberonics, Inc. | Compensation reduction in tissue stimulation therapy |
| US7869885B2 (en) | 2006-04-28 | 2011-01-11 | Cyberonics, Inc | Threshold optimization for tissue stimulation therapy |
| US7869867B2 (en) | 2006-10-27 | 2011-01-11 | Cyberonics, Inc. | Implantable neurostimulator with refractory stimulation |
| US7974701B2 (en) | 2007-04-27 | 2011-07-05 | Cyberonics, Inc. | Dosing limitation for an implantable medical device |
| US8382667B2 (en) | 2010-10-01 | 2013-02-26 | Flint Hills Scientific, Llc | Detecting, quantifying, and/or classifying seizures using multimodal data |
| US8571643B2 (en) | 2010-09-16 | 2013-10-29 | Flint Hills Scientific, Llc | Detecting or validating a detection of a state change from a template of heart rate derivative shape or heart beat wave complex |
| US8337404B2 (en) | 2010-10-01 | 2012-12-25 | Flint Hills Scientific, Llc | Detecting, quantifying, and/or classifying seizures using multimodal data |
| US8204603B2 (en) | 2008-04-25 | 2012-06-19 | Cyberonics, Inc. | Blocking exogenous action potentials by an implantable medical device |
| US8457747B2 (en) | 2008-10-20 | 2013-06-04 | Cyberonics, Inc. | Neurostimulation with signal duration determined by a cardiac cycle |
| US8417344B2 (en) | 2008-10-24 | 2013-04-09 | Cyberonics, Inc. | Dynamic cranial nerve stimulation based on brain state determination from cardiac data |
| US20100191304A1 (en) | 2009-01-23 | 2010-07-29 | Scott Timothy L | Implantable Medical Device for Providing Chronic Condition Therapy and Acute Condition Therapy Using Vagus Nerve Stimulation |
| US8827912B2 (en) | 2009-04-24 | 2014-09-09 | Cyberonics, Inc. | Methods and systems for detecting epileptic events using NNXX, optionally with nonlinear analysis parameters |
| US8239028B2 (en) | 2009-04-24 | 2012-08-07 | Cyberonics, Inc. | Use of cardiac parameters in methods and systems for treating a chronic medical condition |
| US8649871B2 (en) | 2010-04-29 | 2014-02-11 | Cyberonics, Inc. | Validity test adaptive constraint modification for cardiac data used for detection of state changes |
| US8562536B2 (en) | 2010-04-29 | 2013-10-22 | Flint Hills Scientific, Llc | Algorithm for detecting a seizure from cardiac data |
| US8831732B2 (en) | 2010-04-29 | 2014-09-09 | Cyberonics, Inc. | Method, apparatus and system for validating and quantifying cardiac beat data quality |
| US8679009B2 (en) | 2010-06-15 | 2014-03-25 | Flint Hills Scientific, Llc | Systems approach to comorbidity assessment |
| US8641646B2 (en) | 2010-07-30 | 2014-02-04 | Cyberonics, Inc. | Seizure detection using coordinate data |
| US8684921B2 (en) | 2010-10-01 | 2014-04-01 | Flint Hills Scientific Llc | Detecting, assessing and managing epilepsy using a multi-variate, metric-based classification analysis |
| US9504390B2 (en) | 2011-03-04 | 2016-11-29 | Globalfoundries Inc. | Detecting, assessing and managing a risk of death in epilepsy |
| US8725239B2 (en) | 2011-04-25 | 2014-05-13 | Cyberonics, Inc. | Identifying seizures using heart rate decrease |
| US9402550B2 (en) | 2011-04-29 | 2016-08-02 | Cybertronics, Inc. | Dynamic heart rate threshold for neurological event detection |
| US10448839B2 (en) | 2012-04-23 | 2019-10-22 | Livanova Usa, Inc. | Methods, systems and apparatuses for detecting increased risk of sudden death |
| US10220211B2 (en) | 2013-01-22 | 2019-03-05 | Livanova Usa, Inc. | Methods and systems to diagnose depression |
| ITPI20130089A1 (it) * | 2013-10-16 | 2015-04-17 | Scuola Superiore Di Studi Universit Ari E Di Perfe | Sistema per il monitoraggio del carico agente su un impianto protesico. |
| CN109011152B (zh) * | 2018-08-22 | 2022-03-18 | 创领心律管理医疗器械（上海）有限公司 | 起搏器体外测试的固定装置、测试装置与测试方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3668690A (en) * | 1970-06-08 | 1972-06-06 | Ormond Alfred N | Method and apparatus for analog to digital conversion |
| US3825015A (en) * | 1972-12-14 | 1974-07-23 | American Optical Corp | Single catheter for atrial and ventricular stimulation |
| DE2427800A1 (de) * | 1973-06-11 | 1975-02-20 | Gen Electric | Analog-digital-umsetzer |
| NL7700427A (nl) * | 1976-03-03 | 1977-09-06 | Arco Med Prod Co | Inplanteerbare digitale hartgangmaker, welke voorzien is van extern kiesbare bedrijfspara- meters. |
| DE2738871A1 (de) * | 1976-09-29 | 1978-03-30 | Arco Med Prod Co | Herzschrittmacher |
| FR2374024A1 (fr) * | 1976-12-14 | 1978-07-13 | American Hospital Supply Corp | Stimulateur cardiaque implantable avec programmation exterieure de frequence |
| US4232679A (en) * | 1977-01-26 | 1980-11-11 | Pacesetter Systems, Inc. | Programmable human tissue stimulator |
| EP0000986B1 (fr) * | 1977-08-19 | 1982-04-07 | BIOTRONIK Mess- und Therapiegeräte GmbH & Co Ingenieurbüro Berlin | Programmeur pour stimulateur implanté |
| DE2862247D1 (en) * | 1977-08-19 | 1983-06-16 | Biotronik Mess & Therapieg | Programmable, implantable body function control apparatus and method for reprogramming said apparatus |
| DE2861544D1 (en) * | 1977-08-19 | 1982-03-04 | Biotronik Mess & Therapieg | Demand pacer with programmable rate hysteresis |
-
1979
- 1979-07-16 IT IT49768/79A patent/IT1118131B/it active
- 1979-07-17 AU AU48989/79A patent/AU536053B2/en not_active Expired
- 1979-07-18 FR FR7918562A patent/FR2431296A1/fr active Granted
- 1979-07-19 JP JP9209879A patent/JPS5521990A/ja active Granted
- 1979-07-19 SE SE7906205A patent/SE445176B/sv unknown
- 1979-07-20 DE DE19792929498 patent/DE2929498A1/de active Granted
- 1979-07-20 GB GB7925328A patent/GB2026870B/en not_active Expired
- 1979-07-20 GB GB8127414A patent/GB2079610B/en not_active Expired
- 1979-07-20 DE DE2954642A patent/DE2954642C2/de not_active Expired - Lifetime
- 1979-07-20 NL NL7905649A patent/NL7905649A/nl not_active Application Discontinuation
-
1980
- 1980-03-27 FR FR8006814A patent/FR2445659B1/fr not_active Expired
-
1984
- 1984-09-04 AU AU32713/84A patent/AU584310B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2929498A1 (de) | 1980-01-31 |
| AU536053B2 (en) | 1984-04-19 |
| GB2079610A (en) | 1982-01-27 |
| GB2079610B (en) | 1983-04-07 |
| GB2026870B (en) | 1982-12-15 |
| FR2445659A1 (fr) | 1980-07-25 |
| IT7949768A0 (it) | 1979-07-16 |
| SE7906205L (sv) | 1980-01-21 |
| AU3271384A (en) | 1984-12-20 |
| GB2026870A (en) | 1980-02-13 |
| AU4898979A (en) | 1980-01-24 |
| FR2431296B1 (fr) | 1984-01-06 |
| SE445176B (sv) | 1986-06-09 |
| DE2929498C2 (fr) | 1991-07-11 |
| IT1118131B (it) | 1986-02-24 |
| FR2445659B1 (fr) | 1985-11-29 |
| FR2431296A1 (fr) | 1980-02-15 |
| NL7905649A (nl) | 1980-01-22 |
| DE2954642C2 (fr) | 1991-11-07 |
| JPS5521990A (en) | 1980-02-16 |
| AU584310B2 (en) | 1989-05-25 |
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