JPS6235758B2 - - Google Patents
Info
- Publication number
- JPS6235758B2 JPS6235758B2 JP10658784A JP10658784A JPS6235758B2 JP S6235758 B2 JPS6235758 B2 JP S6235758B2 JP 10658784 A JP10658784 A JP 10658784A JP 10658784 A JP10658784 A JP 10658784A JP S6235758 B2 JPS6235758 B2 JP S6235758B2
- Authority
- JP
- Japan
- Prior art keywords
- acetyl
- amino acids
- reaction
- amino acid
- coa
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000008574 D-amino acids Chemical class 0.000 claims description 19
- 239000002253 acid Substances 0.000 claims description 10
- 150000008575 L-amino acids Chemical class 0.000 claims description 9
- LIPOUNRJVLNBCD-UHFFFAOYSA-N acetyl dihydrogen phosphate Chemical compound CC(=O)OP(O)(O)=O LIPOUNRJVLNBCD-UHFFFAOYSA-N 0.000 claims description 8
- 108700023175 Phosphate acetyltransferases Proteins 0.000 claims description 5
- 108020002494 acetyltransferase Proteins 0.000 claims description 5
- 102000005421 acetyltransferase Human genes 0.000 claims description 5
- 239000005515 coenzyme Substances 0.000 claims description 5
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 description 25
- ZSLZBFCDCINBPY-ZSJPKINUSA-N acetyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 ZSLZBFCDCINBPY-ZSJPKINUSA-N 0.000 description 16
- 229940024606 amino acid Drugs 0.000 description 15
- 235000001014 amino acid Nutrition 0.000 description 10
- 238000000034 method Methods 0.000 description 9
- 102000004190 Enzymes Human genes 0.000 description 8
- 108090000790 Enzymes Proteins 0.000 description 8
- 150000001413 amino acids Chemical class 0.000 description 7
- 239000002994 raw material Substances 0.000 description 6
- 108090001066 Racemases and epimerases Proteins 0.000 description 5
- 102000004879 Racemases and epimerases Human genes 0.000 description 5
- ODKSFYDXXFIFQN-UHFFFAOYSA-N Arginine Chemical compound OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 4
- 229930182817 methionine Natural products 0.000 description 4
- 235000006109 methionine Nutrition 0.000 description 4
- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 3
- WFDIJRYMOXRFFG-UHFFFAOYSA-N Acetic anhydride Chemical compound CC(=O)OC(C)=O WFDIJRYMOXRFFG-UHFFFAOYSA-N 0.000 description 3
- 239000004470 DL Methionine Substances 0.000 description 3
- FFEARJCKVFRZRR-UHFFFAOYSA-N methionine Chemical compound CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 description 3
- 230000003287 optical effect Effects 0.000 description 3
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
- -1 N-acetylamino Chemical group 0.000 description 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 2
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 description 2
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 229940110377 dl- arginine Drugs 0.000 description 2
- 238000006911 enzymatic reaction Methods 0.000 description 2
- 239000000178 monomer Substances 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 1
- 108010032178 Amino-acid N-acetyltransferase Proteins 0.000 description 1
- 102000007610 Amino-acid N-acetyltransferase Human genes 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000193403 Clostridium Species 0.000 description 1
- 241000186570 Clostridium kluyveri Species 0.000 description 1
- 239000004471 Glycine Substances 0.000 description 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 description 1
- 229930064664 L-arginine Natural products 0.000 description 1
- 235000014852 L-arginine Nutrition 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 description 1
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 description 1
- 101710150975 N-acyl-L-amino acid amidohydrolase Proteins 0.000 description 1
- 102000004160 Phosphoric Monoester Hydrolases Human genes 0.000 description 1
- 108090000608 Phosphoric Monoester Hydrolases Proteins 0.000 description 1
- 241000235070 Saccharomyces Species 0.000 description 1
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 description 1
- 125000000738 acetamido group Chemical group [H]C([H])([H])C(=O)N([H])[*] 0.000 description 1
- QWCKQJZIFLGMSD-UHFFFAOYSA-N alpha-aminobutyric acid Chemical compound CCC(N)C(O)=O QWCKQJZIFLGMSD-UHFFFAOYSA-N 0.000 description 1
- 238000002306 biochemical method Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 239000003456 ion exchange resin Substances 0.000 description 1
- 229920003303 ion-exchange polymer Polymers 0.000 description 1
- MYWUZJCMWCOHBA-VIFPVBQESA-N methamphetamine Chemical compound CN[C@@H](C)CC1=CC=CC=C1 MYWUZJCMWCOHBA-VIFPVBQESA-N 0.000 description 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
- 230000006340 racemization Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000010189 synthetic method Methods 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10658784A JPS60251892A (ja) | 1984-05-28 | 1984-05-28 | Ｄ−ｎ−アセチルアミノ酸の製法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10658784A JPS60251892A (ja) | 1984-05-28 | 1984-05-28 | Ｄ−ｎ−アセチルアミノ酸の製法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS60251892A JPS60251892A (ja) | 1985-12-12 |
| JPS6235758B2 true JPS6235758B2 (enExample) | 1987-08-04 |
Family
ID=14437325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10658784A Granted JPS60251892A (ja) | 1984-05-28 | 1984-05-28 | Ｄ−ｎ−アセチルアミノ酸の製法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS60251892A (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5157180B2 (ja) * | 2006-01-27 | 2013-03-06 | 味の素株式会社 | Ｌ−アミノ酸の製造法 |
| CN116926139A (zh) * | 2022-04-12 | 2023-10-24 | 元素驱动(杭州)生物科技有限公司 | 一种n-乙酰-d-氨基酸、d-氨基酸、d-氨基酸衍生物的制备方法 |
-
1984
- 1984-05-28 JP JP10658784A patent/JPS60251892A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS60251892A (ja) | 1985-12-12 |
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