JPS6165821A - 合成サ−フアクタント及びそれを有効成分とする肺表面活性物質喪失性無気肺の治療剤 - Google Patents
合成サ−フアクタント及びそれを有効成分とする肺表面活性物質喪失性無気肺の治療剤Info
- Publication number
- JPS6165821A JPS6165821A JP59186529A JP18652984A JPS6165821A JP S6165821 A JPS6165821 A JP S6165821A JP 59186529 A JP59186529 A JP 59186529A JP 18652984 A JP18652984 A JP 18652984A JP S6165821 A JPS6165821 A JP S6165821A
- Authority
- JP
- Japan
- Prior art keywords
- surfactant
- atelectasis
- synthetic
- therapeutic agent
- fatty acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 229940124597 therapeutic agent Drugs 0.000 title claims description 10
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- XIRNKXNNONJFQO-UHFFFAOYSA-N ethyl hexadecanoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC XIRNKXNNONJFQO-UHFFFAOYSA-N 0.000 description 2
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- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- HUHGPYXAVBJSJV-UHFFFAOYSA-N 2-[3,5-bis(2-hydroxyethyl)-1,3,5-triazinan-1-yl]ethanol Chemical compound OCCN1CN(CCO)CN(CCO)C1 HUHGPYXAVBJSJV-UHFFFAOYSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
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- 108091003079 Bovine Serum Albumin Proteins 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 241000700199 Cavia porcellus Species 0.000 description 1
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- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 description 1
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- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 1
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- 229940024606 amino acid Drugs 0.000 description 1
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- 229940124630 bronchodilator Drugs 0.000 description 1
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- 150000001720 carbohydrates Chemical class 0.000 description 1
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- 229910052799 carbon Inorganic materials 0.000 description 1
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- 229960004666 glucagon Drugs 0.000 description 1
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- 238000007912 intraperitoneal administration Methods 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 238000004898 kneading Methods 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
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- 210000002966 serum Anatomy 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- RYYKJJJTJZKILX-UHFFFAOYSA-M sodium octadecanoate Chemical compound [Na+].CCCCCCCCCCCCCCCCCC([O-])=O RYYKJJJTJZKILX-UHFFFAOYSA-M 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
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Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59186529A JPS6165821A (ja) | 1984-09-07 | 1984-09-07 | 合成サ−フアクタント及びそれを有効成分とする肺表面活性物質喪失性無気肺の治療剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59186529A JPS6165821A (ja) | 1984-09-07 | 1984-09-07 | 合成サ−フアクタント及びそれを有効成分とする肺表面活性物質喪失性無気肺の治療剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6165821A true JPS6165821A (ja) | 1986-04-04 |
| JPH028768B2 JPH028768B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1990-02-27 |
Family
ID=16190088
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP59186529A Granted JPS6165821A (ja) | 1984-09-07 | 1984-09-07 | 合成サ−フアクタント及びそれを有効成分とする肺表面活性物質喪失性無気肺の治療剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6165821A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6463526A (en) * | 1987-04-08 | 1989-03-09 | Chiesi Farma Spa | Pulmonary artery surfactant, preparation and drug composition |
| EP0528034A4 (en) * | 1990-05-18 | 1993-03-24 | Tokyo Tanabe Company Limited | Remedy for asthma |
| JP2002529394A (ja) * | 1998-11-10 | 2002-09-10 | ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング | 肺サーファクタント組成物を含有する治療セット |
-
1984
- 1984-09-07 JP JP59186529A patent/JPS6165821A/ja active Granted
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6463526A (en) * | 1987-04-08 | 1989-03-09 | Chiesi Farma Spa | Pulmonary artery surfactant, preparation and drug composition |
| EP0528034A4 (en) * | 1990-05-18 | 1993-03-24 | Tokyo Tanabe Company Limited | Remedy for asthma |
| JP2002529394A (ja) * | 1998-11-10 | 2002-09-10 | ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング | 肺サーファクタント組成物を含有する治療セット |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH028768B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1990-02-27 |
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