JPS6136281A - ベンゾチオフエン下痢止め薬 - Google Patents

ベンゾチオフエン下痢止め薬

Info

Publication number
JPS6136281A
JPS6136281A JP15117785A JP15117785A JPS6136281A JP S6136281 A JPS6136281 A JP S6136281A JP 15117785 A JP15117785 A JP 15117785A JP 15117785 A JP15117785 A JP 15117785A JP S6136281 A JPS6136281 A JP S6136281A
Authority
JP
Japan
Prior art keywords
group
carbon atoms
compound according
formula
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP15117785A
Other languages
English (en)
Japanese (ja)
Inventor
ステイーヴン・ジエームズ・レイ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Pfizer Corp SRL
Original Assignee
Pfizer Corp Belgium
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium, Pfizer Corp SRL filed Critical Pfizer Corp Belgium
Publication of JPS6136281A publication Critical patent/JPS6136281A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Insulating Materials (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
JP15117785A 1984-07-10 1985-07-09 ベンゾチオフエン下痢止め薬 Pending JPS6136281A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848417559A GB8417559D0 (en) 1984-07-10 1984-07-10 Anti-diarrhoeal agents
GB8417559 1984-07-10

Publications (1)

Publication Number Publication Date
JPS6136281A true JPS6136281A (ja) 1986-02-20

Family

ID=10563672

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15117785A Pending JPS6136281A (ja) 1984-07-10 1985-07-09 ベンゾチオフエン下痢止め薬

Country Status (20)

Country Link
US (1) US4654352A (OSRAM)
EP (1) EP0169012A1 (OSRAM)
JP (1) JPS6136281A (OSRAM)
KR (1) KR860001094A (OSRAM)
CN (1) CN85105193A (OSRAM)
AU (1) AU556058B2 (OSRAM)
CS (1) CS249545B2 (OSRAM)
DD (1) DD238792A5 (OSRAM)
DK (1) DK312485A (OSRAM)
ES (1) ES8604557A1 (OSRAM)
FI (1) FI852691A7 (OSRAM)
GB (1) GB8417559D0 (OSRAM)
GR (1) GR851688B (OSRAM)
HU (1) HUT38330A (OSRAM)
IL (1) IL75740A0 (OSRAM)
NO (1) NO852760L (OSRAM)
PL (1) PL254445A1 (OSRAM)
PT (1) PT80786B (OSRAM)
YU (1) YU113985A (OSRAM)
ZA (1) ZA855153B (OSRAM)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4128690A1 (de) * 1991-08-29 1993-03-04 Boehringer Mannheim Gmbh Bicyclische sulfone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US5789436A (en) * 1994-04-11 1998-08-04 Chugai Seiyak Kabushiki Kaisha 4,6 Di-t-butyl-5-hydroxy-2,3-dihydrobenzothiophene
CA2207141A1 (en) * 1996-07-15 1998-01-15 David Thompson Berg Benzothiophene compounds, and uses and formulations thereof
CA2207083A1 (en) * 1996-07-15 1998-01-15 Brian William Grinnell Benzothiophene compounds, and uses and formulations thereof
US5792798A (en) * 1996-07-29 1998-08-11 Eli Lilly And Company Method for inhibiting plasminogen activator inhibitor 1
EP0974584B1 (en) * 1997-02-21 2003-01-15 Takeda Chemical Industries, Ltd. Fused ring compounds, process for producing the same and use thereof
US6251936B1 (en) 1998-05-12 2001-06-26 American Home Products Corporation Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia
HRP20000767A2 (en) * 1998-05-12 2001-10-31 American Home Prod Benzothiophenes, benzofurans and indoles useful in the treatment of insulin resistance and hyperglycemia
ES2233703T3 (es) * 2000-11-02 2005-06-16 F. Hoffmann-La Roche Ag Benzo(b)tiofenos y benzo (d)isotiazoles hipocolesterolemiantes..
US6969730B2 (en) 2001-03-16 2005-11-29 Abbott Laboratories Amines as histamine-3 receptor ligands and their therapeutic applications
WO2006019497A2 (en) * 2004-06-17 2006-02-23 Neurocrine Biosciences, Inc. Sleep-inducing compounds and methods related thereto
JP5180807B2 (ja) 2008-12-24 2013-04-10 三菱重工業株式会社 １段静翼の冷却構造、及びガスタービン

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1174411A (en) * 1966-03-02 1969-12-17 Aspro Nicholas Ltd Novel Benzothiophen Compounds, Compositions containing them and processes for their manufacture
US3598839A (en) * 1969-06-30 1971-08-10 Parke Davis & Co Phenylbenzothiophene compounds
US3944672A (en) * 1972-12-13 1976-03-16 Schering Corporation Method for treating microbial infections
DE2522669A1 (de) * 1974-05-28 1975-12-11 Scherico Ltd Antimikrobielle verbindungen und sie enthaltende zusammensetzungen
US4018893A (en) * 1974-05-28 1977-04-19 Schering Corporation Methods for treating microbial infections
US4137414A (en) * 1977-09-26 1979-01-30 G. D. Searle & Co. 5-Substituted-2-phenylbenzo[b]thiophene-3-alkylamines and related compounds

Also Published As

Publication number Publication date
CN85105193A (zh) 1987-01-28
FI852691A0 (fi) 1985-07-08
EP0169012A1 (en) 1986-01-22
GR851688B (OSRAM) 1985-11-26
YU113985A (en) 1987-08-31
PT80786A (en) 1985-08-01
HUT38330A (en) 1986-05-28
ES544970A0 (es) 1986-02-01
DD238792A5 (de) 1986-09-03
GB8417559D0 (en) 1984-08-15
FI852691L (fi) 1986-01-11
FI852691A7 (fi) 1986-01-11
PL254445A1 (en) 1986-07-15
AU4471385A (en) 1986-01-16
AU556058B2 (en) 1986-10-23
DK312485A (da) 1986-01-11
NO852760L (no) 1986-01-13
ZA855153B (en) 1987-02-25
PT80786B (en) 1987-03-26
DK312485D0 (da) 1985-07-09
KR860001094A (ko) 1986-02-22
CS249545B2 (en) 1987-03-12
US4654352A (en) 1987-03-31
IL75740A0 (en) 1985-11-29
ES8604557A1 (es) 1986-02-01

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