JPS61233A - 水溶性乳漿蛋白質水解物の製造方法 - Google Patents
水溶性乳漿蛋白質水解物の製造方法Info
- Publication number
- JPS61233A JPS61233A JP11911684A JP11911684A JPS61233A JP S61233 A JPS61233 A JP S61233A JP 11911684 A JP11911684 A JP 11911684A JP 11911684 A JP11911684 A JP 11911684A JP S61233 A JPS61233 A JP S61233A
- Authority
- JP
- Japan
- Prior art keywords
- hydrolyzate
- whey protein
- water
- solution
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108010046377 Whey Proteins Proteins 0.000 title claims abstract description 40
- 102000007544 Whey Proteins Human genes 0.000 title claims abstract description 39
- 235000021119 whey protein Nutrition 0.000 title claims abstract description 38
- 238000004519 manufacturing process Methods 0.000 title claims description 11
- 239000004365 Protease Substances 0.000 claims abstract description 19
- 108091005804 Peptidases Proteins 0.000 claims abstract description 18
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims abstract description 18
- 238000010438 heat treatment Methods 0.000 claims abstract description 18
- 239000000243 solution Substances 0.000 claims abstract description 16
- 239000007864 aqueous solution Substances 0.000 claims abstract description 13
- 239000002244 precipitate Substances 0.000 claims abstract description 13
- 108090000145 Bacillolysin Proteins 0.000 claims abstract description 9
- 102000035092 Neutral proteases Human genes 0.000 claims abstract description 9
- 108091005507 Neutral proteases Proteins 0.000 claims abstract description 9
- 241000228212 Aspergillus Species 0.000 claims abstract description 8
- 239000002253 acid Substances 0.000 claims abstract description 7
- 230000003301 hydrolyzing effect Effects 0.000 claims abstract description 4
- 230000002538 fungal effect Effects 0.000 claims description 13
- 239000003531 protein hydrolysate Substances 0.000 claims description 13
- 235000018102 proteins Nutrition 0.000 abstract description 14
- 102000004169 proteins and genes Human genes 0.000 abstract description 14
- 108090000623 proteins and genes Proteins 0.000 abstract description 14
- 238000000034 method Methods 0.000 abstract description 9
- 235000013336 milk Nutrition 0.000 abstract description 5
- 239000008267 milk Substances 0.000 abstract description 5
- 210000004080 milk Anatomy 0.000 abstract description 5
- 239000005018 casein Substances 0.000 abstract description 3
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 abstract description 3
- 235000021240 caseins Nutrition 0.000 abstract description 3
- 235000013351 cheese Nutrition 0.000 abstract description 3
- 238000001035 drying Methods 0.000 abstract description 3
- 239000005862 Whey Substances 0.000 abstract description 2
- 235000015097 nutrients Nutrition 0.000 abstract description 2
- 239000000047 product Substances 0.000 abstract description 2
- 239000012460 protein solution Substances 0.000 abstract 1
- 235000019419 proteases Nutrition 0.000 description 16
- 239000006228 supernatant Substances 0.000 description 16
- 102000004190 Enzymes Human genes 0.000 description 8
- 108090000790 Enzymes Proteins 0.000 description 8
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 8
- 229940088598 enzyme Drugs 0.000 description 8
- 238000011084 recovery Methods 0.000 description 7
- 239000000126 substance Substances 0.000 description 7
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 6
- 238000002835 absorbance Methods 0.000 description 5
- 238000004220 aggregation Methods 0.000 description 5
- 230000002776 aggregation Effects 0.000 description 5
- 230000015572 biosynthetic process Effects 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 241000752058 Rugilus Species 0.000 description 4
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 4
- 235000015872 dietary supplement Nutrition 0.000 description 4
- 238000010790 dilution Methods 0.000 description 4
- 239000012895 dilution Substances 0.000 description 4
- 230000007062 hydrolysis Effects 0.000 description 4
- 238000006460 hydrolysis reaction Methods 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 238000002523 gelfiltration Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 238000010979 pH adjustment Methods 0.000 description 3
- 244000063299 Bacillus subtilis Species 0.000 description 2
- 235000014469 Bacillus subtilis Nutrition 0.000 description 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 102000008192 Lactoglobulins Human genes 0.000 description 2
- 108010060630 Lactoglobulins Proteins 0.000 description 2
- 108010019160 Pancreatin Proteins 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 2
- 239000000920 calcium hydroxide Substances 0.000 description 2
- 229910001861 calcium hydroxide Inorganic materials 0.000 description 2
- 239000000084 colloidal system Substances 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 235000013365 dairy product Nutrition 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000002255 enzymatic effect Effects 0.000 description 2
- 235000020776 essential amino acid Nutrition 0.000 description 2
- 239000003797 essential amino acid Substances 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 210000001819 pancreatic juice Anatomy 0.000 description 2
- 229940055695 pancreatin Drugs 0.000 description 2
- 210000000582 semen Anatomy 0.000 description 2
- WXHLLJAMBQLULT-UHFFFAOYSA-N 2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-n-(2-methyl-6-sulfanylphenyl)-1,3-thiazole-5-carboxamide;hydrate Chemical compound O.C=1C(N2CCN(CCO)CC2)=NC(C)=NC=1NC(S1)=NC=C1C(=O)NC1=C(C)C=CC=C1S WXHLLJAMBQLULT-UHFFFAOYSA-N 0.000 description 1
- 102000009027 Albumins Human genes 0.000 description 1
- 108010088751 Albumins Proteins 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 235000019750 Crude protein Nutrition 0.000 description 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 description 1
- 102000004407 Lactalbumin Human genes 0.000 description 1
- 108090000942 Lactalbumin Proteins 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 108090000526 Papain Proteins 0.000 description 1
- 229920005654 Sephadex Polymers 0.000 description 1
- 239000012507 Sephadex™ Substances 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000004925 denaturation Methods 0.000 description 1
- 230000036425 denaturation Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 230000001804 emulsifying effect Effects 0.000 description 1
- 230000007071 enzymatic hydrolysis Effects 0.000 description 1
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 229960000789 guanidine hydrochloride Drugs 0.000 description 1
- PJJJBBJSCAKJQF-UHFFFAOYSA-N guanidinium chloride Chemical compound [Cl-].NC(N)=[NH2+] PJJJBBJSCAKJQF-UHFFFAOYSA-N 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 229940055729 papain Drugs 0.000 description 1
- 235000019834 papain Nutrition 0.000 description 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000010257 thawing Methods 0.000 description 1
Landscapes
- Peptides Or Proteins (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11911684A JPS61233A (ja) | 1984-06-12 | 1984-06-12 | 水溶性乳漿蛋白質水解物の製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11911684A JPS61233A (ja) | 1984-06-12 | 1984-06-12 | 水溶性乳漿蛋白質水解物の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS61233A true JPS61233A (ja) | 1986-01-06 |
| JPH0582412B2 JPH0582412B2 (enrdf_load_stackoverflow) | 1993-11-18 |
Family
ID=14753323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP11911684A Granted JPS61233A (ja) | 1984-06-12 | 1984-06-12 | 水溶性乳漿蛋白質水解物の製造方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS61233A (enrdf_load_stackoverflow) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02265441A (ja) * | 1988-07-20 | 1990-10-30 | Meiji Milk Prod Co Ltd | 牛乳乳清蛋白質中のβ―ラクトログロブリンの選択的酵素分解方法 |
| US5882705A (en) * | 1993-09-07 | 1999-03-16 | Snow Brand Milk Products Co., Ltd | Micellar whey protein, solution thereof, powder thereof, and foods utilizing same |
| JP2009521955A (ja) * | 2006-01-04 | 2009-06-11 | レプリノ フーズ カンパニー | タンパク質加水分解産物およびそれを作製する方法 |
| JP2012519760A (ja) * | 2009-03-06 | 2012-08-30 | バイオポリマー テクノロジーズ， リミテッド | タンパク質含有フォーム、その製造および使用 |
| US9816019B2 (en) | 2010-06-07 | 2017-11-14 | Evertree | Protein-containing adhesives, and manufacture and use thereof |
| US9873823B2 (en) | 2012-07-30 | 2018-01-23 | Evertree | Protein adhesives containing an anhydride, carboxylic acid, and/or carboxylate salt compound and their use |
| US9909044B2 (en) | 2009-03-06 | 2018-03-06 | Evertree | Protein-containing emulsions and adhesives, and manufacture and use thereof |
| US10125295B2 (en) | 2011-09-09 | 2018-11-13 | Evertree | Protein-containing adhesives, and manufacture and use thereof |
| US11028298B2 (en) | 2011-09-09 | 2021-06-08 | Evertree | Protein-containing adhesives, and manufacture and use thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5854786A (ja) * | 1981-09-28 | 1983-03-31 | Fujitsu Ltd | 映像信号を伝送する無線通信システム |
-
1984
- 1984-06-12 JP JP11911684A patent/JPS61233A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5854786A (ja) * | 1981-09-28 | 1983-03-31 | Fujitsu Ltd | 映像信号を伝送する無線通信システム |
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02265441A (ja) * | 1988-07-20 | 1990-10-30 | Meiji Milk Prod Co Ltd | 牛乳乳清蛋白質中のβ―ラクトログロブリンの選択的酵素分解方法 |
| US5882705A (en) * | 1993-09-07 | 1999-03-16 | Snow Brand Milk Products Co., Ltd | Micellar whey protein, solution thereof, powder thereof, and foods utilizing same |
| JP2009521955A (ja) * | 2006-01-04 | 2009-06-11 | レプリノ フーズ カンパニー | タンパク質加水分解産物およびそれを作製する方法 |
| US9909044B2 (en) | 2009-03-06 | 2018-03-06 | Evertree | Protein-containing emulsions and adhesives, and manufacture and use thereof |
| JP2016211007A (ja) * | 2009-03-06 | 2016-12-15 | バイオポリマー テクノロジーズ， リミテッド | タンパク質含有フォーム、その製造および使用 |
| JP2015180743A (ja) * | 2009-03-06 | 2015-10-15 | バイオポリマー テクノロジーズ， リミテッド | タンパク質含有フォーム、その製造および使用 |
| JP2012519760A (ja) * | 2009-03-06 | 2012-08-30 | バイオポリマー テクノロジーズ， リミテッド | タンパク質含有フォーム、その製造および使用 |
| JP2018087352A (ja) * | 2009-03-06 | 2018-06-07 | バイオポリマー テクノロジーズ， リミテッド | タンパク質含有フォーム、その製造および使用 |
| US10160842B2 (en) | 2009-03-06 | 2018-12-25 | Evertree | Protein-containing foams, manufacture and use thereof |
| US10745601B2 (en) | 2009-03-06 | 2020-08-18 | Evertree | Protein-containing emulsions and adhesives, and manufacture and use thereof |
| US9816019B2 (en) | 2010-06-07 | 2017-11-14 | Evertree | Protein-containing adhesives, and manufacture and use thereof |
| US10465103B2 (en) | 2010-06-07 | 2019-11-05 | Evertree | Protein-containing adhesives, and manufacture and use thereof |
| US10913880B2 (en) | 2010-06-07 | 2021-02-09 | Evertree | Protein-containing adhesives, and manufacture and use thereof |
| US11028298B2 (en) | 2011-09-09 | 2021-06-08 | Evertree | Protein-containing adhesives, and manufacture and use thereof |
| US10125295B2 (en) | 2011-09-09 | 2018-11-13 | Evertree | Protein-containing adhesives, and manufacture and use thereof |
| US11072731B2 (en) | 2011-09-09 | 2021-07-27 | Evertree | Protein-containing adhesives, and manufacture and use thereof |
| US9873823B2 (en) | 2012-07-30 | 2018-01-23 | Evertree | Protein adhesives containing an anhydride, carboxylic acid, and/or carboxylate salt compound and their use |
| US10526516B2 (en) | 2012-07-30 | 2020-01-07 | Evertree | Protein adhesives containing an anhydride, carboxylic acid, and/or carboxylate salt compound and their use |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0582412B2 (enrdf_load_stackoverflow) | 1993-11-18 |
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