JPS6112919B2 - - Google Patents

Info

Publication number
JPS6112919B2
JPS6112919B2 JP7608279A JP7608279A JPS6112919B2 JP S6112919 B2 JPS6112919 B2 JP S6112919B2 JP 7608279 A JP7608279 A JP 7608279A JP 7608279 A JP7608279 A JP 7608279A JP S6112919 B2 JPS6112919 B2 JP S6112919B2
Authority
JP
Japan
Prior art keywords
aspartyl
lower alkyl
alkyl ester
aqueous medium
crystals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP7608279A
Other languages
English (en)
Japanese (ja)
Other versions
JPS55167268A (en
Inventor
Kyotaka Koyama
Mikio Ito
Masaji Kubo
Juji Nonaka
Masao Nakamura
Masayoshi Naruse
Tetsuo Yamatani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Sagami Chemical Research Institute
Tosoh Corp
Original Assignee
Ajinomoto Co Inc
Sagami Chemical Research Institute
Toyo Soda Manufacturing Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc, Sagami Chemical Research Institute, Toyo Soda Manufacturing Co Ltd filed Critical Ajinomoto Co Inc
Priority to JP7608279A priority Critical patent/JPS55167268A/ja
Publication of JPS55167268A publication Critical patent/JPS55167268A/ja
Publication of JPS6112919B2 publication Critical patent/JPS6112919B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
JP7608279A 1979-06-16 1979-06-16 Purification of alpha-l-aspartyl-l-phenylalanine lower alkyl ester Granted JPS55167268A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7608279A JPS55167268A (en) 1979-06-16 1979-06-16 Purification of alpha-l-aspartyl-l-phenylalanine lower alkyl ester

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7608279A JPS55167268A (en) 1979-06-16 1979-06-16 Purification of alpha-l-aspartyl-l-phenylalanine lower alkyl ester

Publications (2)

Publication Number Publication Date
JPS55167268A JPS55167268A (en) 1980-12-26
JPS6112919B2 true JPS6112919B2 (enrdf_load_stackoverflow) 1986-04-10

Family

ID=13594894

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7608279A Granted JPS55167268A (en) 1979-06-16 1979-06-16 Purification of alpha-l-aspartyl-l-phenylalanine lower alkyl ester

Country Status (1)

Country Link
JP (1) JPS55167268A (enrdf_load_stackoverflow)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58177952A (ja) * 1982-04-12 1983-10-18 Ajinomoto Co Inc Ｌ−α−アスパルチル−Ｌ−フエニルアラニンメチルエステルの晶析法
DE3635582A1 (de) * 1986-10-20 1988-04-21 Hoechst Ag Verfahren zur reinigung von n-acyl-aspartam
JPH089584B2 (ja) * 1988-02-12 1996-01-31 ザ ヌトラスウィート カンパニー α―Ｌ―アルパルチル―Ｌ―フェニルアラニンメチルエステル塩酸塩のワンポット製造法

Also Published As

Publication number Publication date
JPS55167268A (en) 1980-12-26

Similar Documents

Publication Publication Date Title
CA1299813C (en) METHOD OF SEPARATING .alpha.-L-ASPARTYL-L-PHENYLALANINE METHYL ESTER THROUGH CRYSTALLIZATION
US6335461B1 (en) Process for purification of aspartame derivative
JPS6112919B2 (enrdf_load_stackoverflow)
JP2970107B2 (ja) α−Ｌ−アスパルチル−Ｌ−フェニルアラニンメチルエステルの製造方法
US4309341A (en) Method for purifying α- L-aspartyl-L-phenylalanine lower alkyl ester
EP0582351A1 (en) Process for the crystallisation of aspartame
JP2946853B2 (ja) アスパルテームの晶析法
JPS6112917B2 (enrdf_load_stackoverflow)
US5349074A (en) Process for pharmaceutical grade high purity hyodeoxycholic acid preparation
US4638081A (en) Process for preparing α-aspartyl-L-phenylalanine methyl ester
CA2017137A1 (en) Method for crystallizing &-l-aspartyl-l-phenylalanine methyl ester
US2779786A (en) Process of preparing 2-semicarbazidoacetic acid
US4962222A (en) Preparation process of α-l-aspartyl-l-phenylalanine methyl ester having low hygroscopicity
KR920003902B1 (ko) 페니실린 유도체의 수화물 및 그 제조방법
KR910001722B1 (ko) 용해성이 개량된 α-L-아스파르틸-L-페닐알라닌메틸 에스테르의 제조법
JP2817255B2 (ja) α―Ｌ―アスパルチル―Ｌ―フェニルアラニンメチルエステルの晶析法
JP3612747B2 (ja) フェニルアラニン無水物結晶の晶析方法
JP2728936B2 (ja) α―Ｌ―アスパルチル―Ｌ―スェニルアラニンメチルエステルの製造方法
JPS6112918B2 (enrdf_load_stackoverflow)
JP3316917B2 (ja) 新規フェニルアラニン塩結晶とその製造法
JP2896259B2 (ja) フェニルアラニンの単離方法
JPS63150295A (ja) α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの分離法
JP2605127B2 (ja) 溶解性の改良されたα―Ｌ―アスパルチル―Ｌ―フエニルアラニンメチルエステルの製造法
JPH0153867B2 (enrdf_load_stackoverflow)
JP2976609B2 (ja) α−Ｌ−アスパルチル−Ｌ−フェニルアラニンメチルエステル又はその塩酸塩の製造法