JPS61122292A - 新規カルバサイクリン中間体の製法 - Google Patents

新規カルバサイクリン中間体の製法

Info

Publication number
JPS61122292A
JPS61122292A JP59240592A JP24059284A JPS61122292A JP S61122292 A JPS61122292 A JP S61122292A JP 59240592 A JP59240592 A JP 59240592A JP 24059284 A JP24059284 A JP 24059284A JP S61122292 A JPS61122292 A JP S61122292A
Authority
JP
Japan
Prior art keywords
group
formula
carbacycline
bicyclo
represented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59240592A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0251559B2 (enExample
Inventor
Shiro Ikegami
池上　四郎
Yasuhiro Torisawa
保廣 鳥澤
Seiji Kurozumi
精二 黒住
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP59240592A priority Critical patent/JPS61122292A/ja
Priority to EP19850905877 priority patent/EP0201608A4/en
Priority to PCT/JP1985/000636 priority patent/WO1986002923A1/ja
Priority to US06/890,690 priority patent/US4978775A/en
Publication of JPS61122292A publication Critical patent/JPS61122292A/ja
Publication of JPH0251559B2 publication Critical patent/JPH0251559B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP59240592A 1984-11-16 1984-11-16 新規カルバサイクリン中間体の製法 Granted JPS61122292A (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP59240592A JPS61122292A (ja) 1984-11-16 1984-11-16 新規カルバサイクリン中間体の製法
EP19850905877 EP0201608A4 (en) 1984-11-16 1985-11-14 METHOD OF PRODUCING BICYCLO-3.3.0-OCTENS.
PCT/JP1985/000636 WO1986002923A1 (fr) 1984-11-16 1985-11-14 Procede de preparation de bicyclo ad3.3.0 bdoctenes
US06/890,690 US4978775A (en) 1984-11-16 1985-11-14 Process for producing bicyclo[3.3.0]octanes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59240592A JPS61122292A (ja) 1984-11-16 1984-11-16 新規カルバサイクリン中間体の製法

Publications (2)

Publication Number Publication Date
JPS61122292A true JPS61122292A (ja) 1986-06-10
JPH0251559B2 JPH0251559B2 (enExample) 1990-11-07

Family

ID=17061794

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59240592A Granted JPS61122292A (ja) 1984-11-16 1984-11-16 新規カルバサイクリン中間体の製法

Country Status (4)

Country Link
US (1) US4978775A (enExample)
EP (1) EP0201608A4 (enExample)
JP (1) JPS61122292A (enExample)
WO (1) WO1986002923A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8429545D0 (en) * 1984-11-22 1985-01-03 May & Baker Ltd Compositions of matter
CA2787755A1 (en) 2010-01-20 2011-07-28 Tolerx, Inc. Immunoregulation by anti-ilt5 antibodies and ilt5-binding antibody fragments
US9023997B2 (en) 2010-01-20 2015-05-05 Merck Sharp & Dohme Corp. Anti-ILT5 antibodies and ILT5-binding antibody fragments
MX360543B (es) 2010-04-09 2018-10-24 Critical Care Diagnostics Inc Anticuerpos st-2 humanos solubles y ensayos.
WO2014151917A1 (en) 2013-03-14 2014-09-25 Ffe Therapeutics Llc Compositions and methods for treating angiogenesis-related disorders
WO2016210241A1 (en) 2015-06-26 2016-12-29 Beth Israel Deaconess Medical Center, Inc. Cancer therapy targeting tetraspanin 33 (tspan33) in myeloid derived suppressor cells
TWI869346B (zh) 2018-05-30 2025-01-11 瑞士商諾華公司 Ｅｎｔｐｄ２抗體、組合療法、及使用該等抗體和組合療法之方法
UY38251A (es) 2018-06-01 2019-12-31 Novartis Ag Moléculas de unión contra bcma y usos de las mismas
UY38407A (es) 2018-10-15 2020-05-29 Novartis Ag Anticuerpos estabilizadores de trem2
US12037378B2 (en) 2019-05-21 2024-07-16 Novartis Ag Variant CD58 domains and uses thereof
CU20210096A7 (es) 2019-05-21 2022-06-06 Novartis Ag Moléculas de unión a cd19
WO2020254861A1 (en) 2019-06-19 2020-12-24 Ovatrition Ltd. Antibody-mediated neutralization of beta-lactamases
EP4031578A1 (en) 2019-09-18 2022-07-27 Novartis AG Entpd2 antibodies, combination therapies, and methods of using the antibodies and combination therapies
TW202124446A (zh) 2019-09-18 2021-07-01 瑞士商諾華公司 與ｅｎｔｐｄ２抗體之組合療法
PH12022551166A1 (en) 2019-11-15 2023-10-02 Pliant Therapeutics Inc Compositions and methods for activation of integrins
US20250215081A1 (en) 2020-11-06 2025-07-03 Novartis Ag Anti-cd19 agent and b cell targeting agent combination therapy for treating b cell malignancies
KR20230104651A (ko) 2020-11-06 2023-07-10 노파르티스 아게 Cd19 결합 분자 및 이의 용도
EP4284510A1 (en) 2021-01-29 2023-12-06 Novartis AG Dosage regimes for anti-cd73 and anti-entpd2 antibodies and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3275542D1 (en) * 1981-11-13 1987-04-09 Teijin Ltd Process for prostaglandin e1, production and novel delta 7-prostaglandines e and 7-hydroxyprostaglandins e

Also Published As

Publication number Publication date
WO1986002923A1 (fr) 1986-05-22
EP0201608A4 (en) 1987-03-30
JPH0251559B2 (enExample) 1990-11-07
US4978775A (en) 1990-12-18
EP0201608A1 (en) 1986-11-20

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