JPS61103876A - 新規な1,2,4‐トリアゾロ‐カルバメート化合物 - Google Patents

新規な1,2,4‐トリアゾロ‐カルバメート化合物

Info

Publication number
JPS61103876A
JPS61103876A JP60236563A JP23656385A JPS61103876A JP S61103876 A JPS61103876 A JP S61103876A JP 60236563 A JP60236563 A JP 60236563A JP 23656385 A JP23656385 A JP 23656385A JP S61103876 A JPS61103876 A JP S61103876A
Authority
JP
Japan
Prior art keywords
carbon atoms
group
methyl
formula
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP60236563A
Other languages
English (en)
Japanese (ja)
Inventor
カール‐ハインツ ウエーバー
デイエター ヒンツエン
フランツ ヨゼフ クーン
エーリツヒ レール
ヴイルヘルム フロールケ
ヴオルフガング トロガー
ヘルムツト エンシンガ
ゲルハルト ヴアルサー
アルブレヒト ハレウス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Publication of JPS61103876A publication Critical patent/JPS61103876A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP60236563A 1984-10-27 1985-10-24 新規な1,2,4‐トリアゾロ‐カルバメート化合物 Pending JPS61103876A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19843439450 DE3439450A1 (de) 1984-10-27 1984-10-27 1,2,4-triazolo-carbamate und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
DE3439450.8 1984-10-27

Publications (1)

Publication Number Publication Date
JPS61103876A true JPS61103876A (ja) 1986-05-22

Family

ID=6248953

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60236563A Pending JPS61103876A (ja) 1984-10-27 1985-10-24 新規な1,2,4‐トリアゾロ‐カルバメート化合物

Country Status (22)

Country Link
US (1) US4732900A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0180115A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS61103876A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR860003240A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU576393B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1244030A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CS (2) CS255897B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (1) DD236928A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3439450A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK491385A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (2) ES8701738A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI854178A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR852581B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU193351B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL76823A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO854276L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ213969A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH22446A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (2) PL255940A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT81370B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SU (2) SU1436873A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA858195B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01242526A (ja) * 1988-03-23 1989-09-27 Takeda Chem Ind Ltd カルバメート化合物

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5331002A (en) * 1990-04-19 1994-07-19 Merrell Dow Pharmaceuticals Inc. 5-aryl-4-alkyl-3H-1,2,4-triazole-3-thiones useful as memory enhancers
US5100906A (en) * 1990-04-19 1992-03-31 Merrell Dow Pharmaceuticals Inc. 5-aryl-4-alkyl-3h-1,2,4-triazole-3-thiones useful as memory enhancers
DE4234801A1 (de) * 1992-10-15 1994-04-21 Bayer Ag Sulfonylaminocarbonyltriazolinone
DE4425144A1 (de) * 1994-07-15 1996-01-18 Basf Ag Triazolverbindungen und deren Verwendung
US5728834A (en) * 1996-11-14 1998-03-17 Wyckoff Chemical Company, Inc. Process for preparation of 4-aryl-1,2,4-triazol-3-ones
BRPI0509172A (pt) * 2004-03-26 2007-08-28 Amphora Discovery Corp pelo menos uma entidade quìmica, composição farmacêutica, métodos para tratar um paciente, para inibir pelo menos uma enzima que utiliza atp, e para tratar pelo menos uma doença, uso de pelo menos uma entidade quìmica, e, método para a fabricação de um medicamento
AU2006203845A1 (en) * 2005-01-10 2006-07-13 Alexandros Makriyannis Novel heteropyrrole analogs acting on cannabiniod receptors
US8853205B2 (en) 2005-01-10 2014-10-07 University Of Connecticut Heteropyrrole analogs acting on cannabinoid receptors
US10053444B2 (en) 2009-02-19 2018-08-21 University Of Connecticut Cannabinergic nitrate esters and related analogs
CA3125847A1 (en) 2020-07-27 2022-01-27 Makscientific, Llc Process for making biologically active compounds and intermediates thereof
US12054480B2 (en) 2020-07-31 2024-08-06 Makscientific, Llc Compounds for treating cannabinoid toxicity and acute cannabinoid overdose
CN115991698B (zh) * 2022-11-03 2024-03-29 广东中科药物研究有限公司 一种杂环化合物及其制备方法与应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB681376A (en) * 1949-11-23 1952-10-22 Geigy Ag J R Manufacture of heterocyclic carbamic acid derivatives and their use as agents for combating pests
NL7112373A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1970-09-25 1972-03-28
US4209515A (en) * 1974-06-14 1980-06-24 Ciba-Geigy Corporation Triazole derivatives
US4160839A (en) * 1976-03-01 1979-07-10 Gulf Oil Corporation Carbamyltriazole insecticides
JPS59199681A (ja) * 1983-04-26 1984-11-12 Ube Ind Ltd 1,2,4−トリアゾ−ル−3−カルボン酸アミド類の製造法
FI850994A7 (fi) * 1984-03-16 1985-09-17 Ciba Geigy Ag Menetelmä uusien 1,2,4 -triatsasykloalkadieenijohdannaisten valmistamiseksi.
US4610717A (en) * 1985-11-26 1986-09-09 Shell Oil Company Certain 5-(R-oxy)-1-phenyl or (3-(trifluoromethyl)phenyl)triazoles, useful for controlling undesired plant growth

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01242526A (ja) * 1988-03-23 1989-09-27 Takeda Chem Ind Ltd カルバメート化合物

Also Published As

Publication number Publication date
EP0180115A3 (de) 1987-01-21
AU4909485A (en) 1986-05-01
ES8704468A1 (es) 1987-04-01
AU576393B2 (en) 1988-08-25
PH22446A (en) 1988-09-12
DE3439450A1 (de) 1986-05-07
PT81370A (de) 1985-11-01
ES554373A0 (es) 1987-04-01
CS255877B2 (en) 1988-03-15
HU193351B (en) 1987-09-28
HUT40091A (en) 1986-11-28
FI854178A0 (fi) 1985-10-25
NO854276L (no) 1986-04-28
SU1436873A3 (ru) 1988-11-07
PT81370B (de) 1987-08-20
CS255897B2 (en) 1988-03-15
ZA858195B (en) 1987-06-24
FI854178L (fi) 1986-04-28
FI854178A7 (fi) 1986-04-28
EP0180115A2 (de) 1986-05-07
KR860003240A (ko) 1986-05-21
CA1244030A (en) 1988-11-01
SU1429934A3 (ru) 1988-10-07
PL255940A1 (en) 1987-07-13
PL264492A1 (en) 1987-11-30
NZ213969A (en) 1987-11-27
DD236928A5 (de) 1986-06-25
GR852581B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1986-02-26
IL76823A0 (en) 1986-02-28
ES548206A0 (es) 1986-12-01
ES8701738A1 (es) 1986-12-01
DK491385A (da) 1986-04-28
US4732900A (en) 1988-03-22
DK491385D0 (da) 1985-10-25

Similar Documents

Publication Publication Date Title
EP1448560B1 (en) 3-SUBSTITUTED OXINDOLE beta 3 AGONISTS
DE60320012T2 (de) Aminoheterocyclen als vr-1 antagonisten zur behandlung von schmerzen
EP1742945B1 (de) Substituierte phenylaminopyrimidine
NZ207156A (en) (2 quinazolinyl)-oxalkylamide derivatives and pharmaceutical compositions
JPH0739387B2 (ja) 新規1−ベンジル−アミノアルキル−ピロリジノン化合物及びその製造方法
JPS61103876A (ja) 新規な1,2,4‐トリアゾロ‐カルバメート化合物
US3993656A (en) 1,8-Naphthyridine compounds
NO163816B (no) Analogifremgangsmaate for fremstilling av nye, terapeutiskaktive piperazinderivater.
US4782055A (en) Imidazopyridine compounds useful in the treatment of ulcers
KR960010346B1 (ko) 4(3h)-퀴나졸리논 유도체, 이의 제조방법 및 약제학적 조성물
CH635586A5 (de) Verfahren zur herstellung von 1,3-dihydroimidazo(4,5-b)pyridin-2-onen.
US4179563A (en) 3-Aryloxy-substituted-aminopyridines and methods for their production
JPS5989679A (ja) ピラゾロ〔3,4−b〕ピリジン誘導体類およびそれらの製造法
EP0068833B1 (en) Pyrimidinone derivatives and pharmaceutical compositions containing them
JPH0517904B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA1084929A (en) 1,2,4-triazolo 4,3-b pyridazin-3-ones
US4672117A (en) Antipsychotic gamma-carbolines
PL93127B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
US4082845A (en) 3-(1-Piperazinyl)-pyrido[2,3-b]pyrazines
WO1992021679A1 (de) NEUE HETARYLOXY-β-CARBOLINE, DEREN HERSTELLUNG UND VERWENDUNG IN ARZNEIMITTELN
US4048184A (en) 6-Phenyl-2H-pyrazolo[3,4-b]pyridines
DD202563A5 (de) Verfahren zur herstellung von 1,5-diphenylpyrazolin-3-on-verbindungen
US5187277A (en) DL-3-[4-[4-(2-pyridyl)-1-piperazinyl]-butyl]-1,8,8-trimethyl-3-azabicyclo[(3]octane-2,4-dione having psychotropic and antiemetic effect
CS244446B2 (en) Method of pyrimidone derivatives production
US4066644A (en) Pyrazolo [1,5-a]pyrido[3,2-e]pyrimidine-7-carboxylic acid heterocyclic derivatives