JPS60186502A - 放射性医薬品とその調製用高分子化合物 - Google Patents
放射性医薬品とその調製用高分子化合物Info
- Publication number
- JPS60186502A JPS60186502A JP59258139A JP25813984A JPS60186502A JP S60186502 A JPS60186502 A JP S60186502A JP 59258139 A JP59258139 A JP 59258139A JP 25813984 A JP25813984 A JP 25813984A JP S60186502 A JPS60186502 A JP S60186502A
- Authority
- JP
- Japan
- Prior art keywords
- solution
- physiologically active
- labeled
- gallium
- active substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/558,333 US4666697A (en) | 1982-12-08 | 1983-12-05 | Radioactive diagnostic agent |
US558333 | 1983-12-05 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62268981A Division JPS63225601A (ja) | 1983-12-05 | 1987-10-24 | 放射性医薬品調製用高分子化合物 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS60186502A true JPS60186502A (ja) | 1985-09-24 |
JPS641449B2 JPS641449B2 (enrdf_load_stackoverflow) | 1989-01-11 |
Family
ID=24229141
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP59258139A Granted JPS60186502A (ja) | 1983-12-05 | 1984-12-05 | 放射性医薬品とその調製用高分子化合物 |
JP59258138A Granted JPS60192703A (ja) | 1983-12-05 | 1984-12-05 | 少なくとも1個の遊離ホルミル基を有する高分子化合物 |
JP62268981A Granted JPS63225601A (ja) | 1983-12-05 | 1987-10-24 | 放射性医薬品調製用高分子化合物 |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP59258138A Granted JPS60192703A (ja) | 1983-12-05 | 1984-12-05 | 少なくとも1個の遊離ホルミル基を有する高分子化合物 |
JP62268981A Granted JPS63225601A (ja) | 1983-12-05 | 1987-10-24 | 放射性医薬品調製用高分子化合物 |
Country Status (1)
Country | Link |
---|---|
JP (3) | JPS60186502A (enrdf_load_stackoverflow) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2014167016A (ja) * | 2014-05-09 | 2014-09-11 | Inst Natl De La Sante & De La Recherche Medical | 変性病変の診断のためのリガンドとしてのフコイダン |
JP2018502282A (ja) * | 2014-11-13 | 2018-01-25 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 高速でラベル化されたn−グリカンに対する液体クロマトグラフィー較正方法 |
US10416166B2 (en) | 2011-09-28 | 2019-09-17 | Waters Technologies Corporation | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals |
US10436790B2 (en) | 2011-09-28 | 2019-10-08 | Waters Technologies Corporation | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals |
US11035832B2 (en) | 2016-06-21 | 2021-06-15 | Waters Technologies Corporation | Methods of electrospray ionization of glycans modified with amphipathic, strongly basic moieties |
US11061023B2 (en) | 2016-06-21 | 2021-07-13 | Waters Technologies Corporation | Fluorescence tagging of glycans and other biomolecules through reductive amination for enhanced MS signals |
US11150248B2 (en) | 2016-07-01 | 2021-10-19 | Waters Technologies Corporation | Methods for the rapid preparation of labeled glycosylamines from complex matrices using molecular weight cut off filtration and on-filter deglycosylation |
US11352325B2 (en) | 2011-09-28 | 2022-06-07 | Waters Technologies Corporation | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals |
US11371996B2 (en) | 2014-10-30 | 2022-06-28 | Waters Technologies Corporation | Methods for the rapid preparation of labeled glycosylamines and for the analysis of glycosylated biomolecules producing the same |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5672334A (en) * | 1991-01-16 | 1997-09-30 | Access Pharmaceuticals, Inc. | Invivo agents comprising cationic metal chelators with acidic saccharides and glycosaminoglycans |
US5707604A (en) * | 1986-11-18 | 1998-01-13 | Access Pharmaceuticals, Inc. | Vivo agents comprising metal-ion chelates with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles |
US6106866A (en) * | 1995-07-31 | 2000-08-22 | Access Pharmaceuticals, Inc. | In vivo agents comprising cationic drugs, peptides and metal chelators with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles, including tumor sites |
-
1984
- 1984-12-05 JP JP59258139A patent/JPS60186502A/ja active Granted
- 1984-12-05 JP JP59258138A patent/JPS60192703A/ja active Granted
-
1987
- 1987-10-24 JP JP62268981A patent/JPS63225601A/ja active Granted
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10416166B2 (en) | 2011-09-28 | 2019-09-17 | Waters Technologies Corporation | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals |
US10436790B2 (en) | 2011-09-28 | 2019-10-08 | Waters Technologies Corporation | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals |
US11352325B2 (en) | 2011-09-28 | 2022-06-07 | Waters Technologies Corporation | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals |
US11448652B2 (en) | 2011-09-28 | 2022-09-20 | Waters Technologies Corporation | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals |
JP2014167016A (ja) * | 2014-05-09 | 2014-09-11 | Inst Natl De La Sante & De La Recherche Medical | 変性病変の診断のためのリガンドとしてのフコイダン |
US11371996B2 (en) | 2014-10-30 | 2022-06-28 | Waters Technologies Corporation | Methods for the rapid preparation of labeled glycosylamines and for the analysis of glycosylated biomolecules producing the same |
US12158472B2 (en) | 2014-10-30 | 2024-12-03 | Waters Technologies Corporation | Methods for the rapid preparation of labeled glycosylamines and for the analysis of glycosylated biomolecules producing the same |
JP2018502282A (ja) * | 2014-11-13 | 2018-01-25 | ウオーターズ・テクノロジーズ・コーポレイシヨン | 高速でラベル化されたn−グリカンに対する液体クロマトグラフィー較正方法 |
US10502720B2 (en) | 2014-11-13 | 2019-12-10 | Waters Technologies Corporation | Methods for liquid chromatography calibration for rapid labeled N-glycans |
US11035832B2 (en) | 2016-06-21 | 2021-06-15 | Waters Technologies Corporation | Methods of electrospray ionization of glycans modified with amphipathic, strongly basic moieties |
US11061023B2 (en) | 2016-06-21 | 2021-07-13 | Waters Technologies Corporation | Fluorescence tagging of glycans and other biomolecules through reductive amination for enhanced MS signals |
US11150248B2 (en) | 2016-07-01 | 2021-10-19 | Waters Technologies Corporation | Methods for the rapid preparation of labeled glycosylamines from complex matrices using molecular weight cut off filtration and on-filter deglycosylation |
Also Published As
Publication number | Publication date |
---|---|
JPS6353201B2 (enrdf_load_stackoverflow) | 1988-10-21 |
JPS641449B2 (enrdf_load_stackoverflow) | 1989-01-11 |
JPH0548761B2 (enrdf_load_stackoverflow) | 1993-07-22 |
JPS60192703A (ja) | 1985-10-01 |
JPS63225601A (ja) | 1988-09-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK172629B1 (da) | Reaktive højmolekylære forbindelser med mindst én fri aminogruppe, højmolekylære forbindelser kombineret med et fysiologisk | |
US5032678A (en) | Radio labeled high molecular compound comprising unit of asialoglycoprotein acceptor-directing compound and unit of chelate forming compound chemically bonded thereto | |
KR860000843B1 (ko) | 방사성 진단제 및 그를 위한 비 방사성 담체의 제조방법 | |
US5130118A (en) | Methods and materials for the preparation of metal labelled antibody solutions | |
JPH036124B2 (enrdf_load_stackoverflow) | ||
JPS58126817A (ja) | 放射性核種標識タンパク質、とくに抗体または抗体断片の製造法 | |
JPS60186502A (ja) | 放射性医薬品とその調製用高分子化合物 | |
EP0315188B1 (en) | Methods and materials for the preparation of metal labelled antibody solutions | |
JP2564459B2 (ja) | 放射性医薬品調製用キャリヤー | |
JP2548711B2 (ja) | アミノ基と2官能性配位子を有する反応性高分子化合物とその利用 | |
JP2677543B2 (ja) | 生理活性物質結合高分子化合物および当該化合物を含む放射性医薬品調製用キャリアー | |
JPH0414084B2 (enrdf_load_stackoverflow) | ||
JP2677544B2 (ja) | 放射性金属元素結合高分子化合物および当該化合物を含む放射性医薬品 | |
JPH047329B2 (enrdf_load_stackoverflow) | ||
JPS63170389A (ja) | 放射性医薬品とその調製用高分子化合物 | |
JPH0615478B2 (ja) | 放射性医薬品とその調製用高分子化合物 | |
JPH01176000A (ja) | 放射性医薬品とその調製用高分子化合物 | |
JPH0460974B2 (enrdf_load_stackoverflow) | ||
JPH0421682B2 (enrdf_load_stackoverflow) | ||
JPH0433767B2 (enrdf_load_stackoverflow) |