JPS60158115A - プラズミノーゲンアクチベーターの製造法 - Google Patents

プラズミノーゲンアクチベーターの製造法

Info

Publication number
JPS60158115A
JPS60158115A JP59013397A JP1339784A JPS60158115A JP S60158115 A JPS60158115 A JP S60158115A JP 59013397 A JP59013397 A JP 59013397A JP 1339784 A JP1339784 A JP 1339784A JP S60158115 A JPS60158115 A JP S60158115A
Authority
JP
Japan
Prior art keywords
kym
substance
culture
activity
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59013397A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0569506B2 (enrdf_load_stackoverflow
Inventor
Masaru Imada
今田　勝
Hiroshi Yoshiyama
吉山　博
Munehiro Oda
宗宏 小田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Dairies Corp
Original Assignee
Meiji Milk Products Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Milk Products Co Ltd filed Critical Meiji Milk Products Co Ltd
Priority to JP59013397A priority Critical patent/JPS60158115A/ja
Priority to NL8500132A priority patent/NL8500132A/nl
Priority to GB08501532A priority patent/GB2153366B/en
Priority to CA000472999A priority patent/CA1275062A/en
Priority to DE19853502760 priority patent/DE3502760A1/de
Priority to FR8501183A priority patent/FR2558848B1/fr
Priority to BE0/214409A priority patent/BE901598A/fr
Publication of JPS60158115A publication Critical patent/JPS60158115A/ja
Publication of JPH0569506B2 publication Critical patent/JPH0569506B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP59013397A 1984-01-30 1984-01-30 プラズミノーゲンアクチベーターの製造法 Granted JPS60158115A (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP59013397A JPS60158115A (ja) 1984-01-30 1984-01-30 プラズミノーゲンアクチベーターの製造法
NL8500132A NL8500132A (nl) 1984-01-30 1985-01-19 Plasmogeen activeringsmiddel kym.
GB08501532A GB2153366B (en) 1984-01-30 1985-01-22 Plasminogen activator
CA000472999A CA1275062A (en) 1984-01-30 1985-01-28 Plasminogen activator kym
DE19853502760 DE3502760A1 (de) 1984-01-30 1985-01-28 Plasminogen-aktivator kym
FR8501183A FR2558848B1 (fr) 1984-01-30 1985-01-29 Activeur de plasminogene kym, procede de preparation par culture d'un mutant de rhabdomyosarcome humain et composition pharmaceutique le renfermant dotee d'une activite thrombolytique
BE0/214409A BE901598A (fr) 1984-01-30 1985-01-29 Activeur de plasminogene kym.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59013397A JPS60158115A (ja) 1984-01-30 1984-01-30 プラズミノーゲンアクチベーターの製造法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP60079300A Division JPS611382A (ja) 1985-04-16 1985-04-16 変異株ｋｙｍ−ａ

Publications (2)

Publication Number Publication Date
JPS60158115A true JPS60158115A (ja) 1985-08-19
JPH0569506B2 JPH0569506B2 (enrdf_load_stackoverflow) 1993-10-01

Family

ID=11831979

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59013397A Granted JPS60158115A (ja) 1984-01-30 1984-01-30 プラズミノーゲンアクチベーターの製造法

Country Status (7)

Country Link
JP (1) JPS60158115A (enrdf_load_stackoverflow)
BE (1) BE901598A (enrdf_load_stackoverflow)
CA (1) CA1275062A (enrdf_load_stackoverflow)
DE (1) DE3502760A1 (enrdf_load_stackoverflow)
FR (1) FR2558848B1 (enrdf_load_stackoverflow)
GB (1) GB2153366B (enrdf_load_stackoverflow)
NL (1) NL8500132A (enrdf_load_stackoverflow)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6427472A (en) * 1987-07-21 1989-01-30 Meiji Milk Prod Co Ltd Production of human tissue plasminogen activator and cell strain using therein

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5728009A (en) * 1980-06-11 1982-02-15 Leuven Res & Dev Vzw Novel plasminogen activator and drug having thrombosis dissolving activity

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3015699C2 (de) * 1979-04-26 1982-07-15 Asahi Kasei Kogyo K.K., Osaka Herstellung eines Plasminogen-Aktivators
WO1981001417A1 (en) * 1979-11-13 1981-05-28 S Husain Isolation of plasminogen activators useful as therapeutic and diagnostic agents
JPS5852634B2 (ja) * 1980-12-05 1983-11-24 株式会社林原生物化学研究所 ウロキナ−ゼの製造法
IL63317A (en) * 1981-07-15 1985-05-31 Yeda Res & Dev Production of plasminogen activator
ZA831399B (en) * 1982-03-05 1984-02-29 Health Lab Service Board New fibrinolytic enzymes and methods for their production and pharmaceutical compositions containing them
JPS5913732A (ja) * 1982-07-16 1984-01-24 Mitsui Toatsu Chem Inc 血栓溶解剤
JPS5951220A (ja) * 1982-08-02 1984-03-24 Asahi Chem Ind Co Ltd 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5728009A (en) * 1980-06-11 1982-02-15 Leuven Res & Dev Vzw Novel plasminogen activator and drug having thrombosis dissolving activity

Also Published As

Publication number Publication date
BE901598A (fr) 1985-07-29
DE3502760A1 (de) 1985-08-08
GB2153366A (en) 1985-08-21
CA1275062A (en) 1990-10-09
FR2558848B1 (fr) 1989-06-09
NL8500132A (nl) 1985-08-16
GB2153366B (en) 1988-05-18
JPH0569506B2 (enrdf_load_stackoverflow) 1993-10-01
GB8501532D0 (en) 1985-02-20
FR2558848A1 (fr) 1985-08-02

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