JPS6015613B2 - ４―ｎ―アセチルアミノベンゾールスルホクロリドの分離及び精製法 - Google Patents
４―ｎ―アセチルアミノベンゾールスルホクロリドの分離及び精製法Info
- Publication number
- JPS6015613B2 JPS6015613B2 JP2659676A JP2659676A JPS6015613B2 JP S6015613 B2 JPS6015613 B2 JP S6015613B2 JP 2659676 A JP2659676 A JP 2659676A JP 2659676 A JP2659676 A JP 2659676A JP S6015613 B2 JPS6015613 B2 JP S6015613B2
- Authority
- JP
- Japan
- Prior art keywords
- sulfochloride
- precipitation
- acetylaminobenzole
- water
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- XTHPWXDJESJLNJ-UHFFFAOYSA-N sulfurochloridic acid Chemical compound OS(Cl)(=O)=O XTHPWXDJESJLNJ-UHFFFAOYSA-N 0.000 title claims description 20
- 238000000034 method Methods 0.000 title claims description 17
- 238000000746 purification Methods 0.000 title claims 3
- 238000000926 separation method Methods 0.000 title claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 20
- 238000001556 precipitation Methods 0.000 claims description 17
- 238000000354 decomposition reaction Methods 0.000 claims description 16
- 239000011541 reaction mixture Substances 0.000 claims description 16
- 239000000203 mixture Substances 0.000 claims description 14
- 238000001816 cooling Methods 0.000 claims description 7
- KEQGZUUPPQEDPF-UHFFFAOYSA-N 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione Chemical compound CC1(C)N(Cl)C(=O)N(Cl)C1=O KEQGZUUPPQEDPF-UHFFFAOYSA-N 0.000 claims description 6
- FZERHIULMFGESH-UHFFFAOYSA-N N-phenylacetamide Chemical compound CC(=O)NC1=CC=CC=C1 FZERHIULMFGESH-UHFFFAOYSA-N 0.000 claims description 6
- 238000006243 chemical reaction Methods 0.000 claims description 5
- 238000005336 cracking Methods 0.000 claims description 4
- 229960001413 acetanilide Drugs 0.000 claims description 3
- 239000006227 byproduct Substances 0.000 claims description 2
- IDWLQQCLPXEHCU-UHFFFAOYSA-N aniline;sulfurochloridic acid Chemical compound OS(Cl)(=O)=O.NC1=CC=CC=C1 IDWLQQCLPXEHCU-UHFFFAOYSA-N 0.000 claims 1
- 239000011521 glass Substances 0.000 description 5
- 239000007795 chemical reaction product Substances 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 3
- 238000005260 corrosion Methods 0.000 description 3
- 230000007797 corrosion Effects 0.000 description 3
- 239000013505 freshwater Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- OAHKWDDSKCRNFE-UHFFFAOYSA-N phenylmethanesulfonyl chloride Chemical compound ClS(=O)(=O)CC1=CC=CC=C1 OAHKWDDSKCRNFE-UHFFFAOYSA-N 0.000 description 2
- 239000002244 precipitate Substances 0.000 description 2
- 238000010626 work up procedure Methods 0.000 description 2
- XMTQQYYKAHVGBJ-UHFFFAOYSA-N 3-(3,4-DICHLOROPHENYL)-1,1-DIMETHYLUREA Chemical compound CN(C)C(=O)NC1=CC=C(Cl)C(Cl)=C1 XMTQQYYKAHVGBJ-UHFFFAOYSA-N 0.000 description 1
- GRDXCFKBQWDAJH-UHFFFAOYSA-N 4-acetamidobenzenesulfonyl chloride Chemical compound CC(=O)NC1=CC=C(S(Cl)(=O)=O)C=C1 GRDXCFKBQWDAJH-UHFFFAOYSA-N 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000012736 aqueous medium Substances 0.000 description 1
- 239000012267 brine Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000005293 duran Substances 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 238000007730 finishing process Methods 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- KERKSHQWMCWPBT-UHFFFAOYSA-N n-phenylacetamide;sulfurochloridic acid Chemical compound OS(Cl)(=O)=O.CC(=O)NC1=CC=CC=C1 KERKSHQWMCWPBT-UHFFFAOYSA-N 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 238000013021 overheating Methods 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 238000007086 side reaction Methods 0.000 description 1
- HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 229940124530 sulfonamide Drugs 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19752510669 DE2510669C2 (de) | 1975-03-12 | 1975-03-12 | Verfahren zur Isolierung von gereinigtem 4-N-Acetylaminobenzolsulfochlorid |
| DE2510669.8 | 1975-03-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS51125351A JPS51125351A (en) | 1976-11-01 |
| JPS6015613B2 true JPS6015613B2 (ja) | 1985-04-20 |
Family
ID=5941089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2659676A Expired JPS6015613B2 (ja) | 1975-03-12 | 1976-03-11 | ４―ｎ―アセチルアミノベンゾールスルホクロリドの分離及び精製法 |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS6015613B2 (enrdf_load_stackoverflow) |
| DD (1) | DD123323A5 (enrdf_load_stackoverflow) |
| DE (1) | DE2510669C2 (enrdf_load_stackoverflow) |
| DK (1) | DK157809C (enrdf_load_stackoverflow) |
| FR (1) | FR2303793A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1542958A (enrdf_load_stackoverflow) |
| IN (1) | IN144395B (enrdf_load_stackoverflow) |
| IT (1) | IT1055747B (enrdf_load_stackoverflow) |
| NL (1) | NL187067C (enrdf_load_stackoverflow) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD3428A (enrdf_load_stackoverflow) * |
-
1975
- 1975-03-12 DE DE19752510669 patent/DE2510669C2/de not_active Expired
- 1975-12-16 NL NL7514639A patent/NL187067C/xx not_active IP Right Cessation
-
1976
- 1976-01-07 IT IT6702076A patent/IT1055747B/it active
- 1976-01-15 DD DD19082576A patent/DD123323A5/xx unknown
- 1976-03-09 DK DK99476A patent/DK157809C/da not_active IP Right Cessation
- 1976-03-11 GB GB972876A patent/GB1542958A/en not_active Expired
- 1976-03-11 JP JP2659676A patent/JPS6015613B2/ja not_active Expired
- 1976-03-12 FR FR7607104A patent/FR2303793A1/fr active Granted
-
1977
- 1977-02-18 IN IN237/CAL/77A patent/IN144395B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS51125351A (en) | 1976-11-01 |
| NL187067C (nl) | 1991-05-16 |
| DK99476A (da) | 1976-09-13 |
| IN144395B (enrdf_load_stackoverflow) | 1978-04-29 |
| IT1055747B (it) | 1982-01-11 |
| NL187067B (nl) | 1990-12-17 |
| DD123323A5 (enrdf_load_stackoverflow) | 1976-12-12 |
| DK157809C (da) | 1990-07-16 |
| FR2303793B1 (enrdf_load_stackoverflow) | 1979-06-01 |
| NL7514639A (nl) | 1976-09-14 |
| DE2510669C2 (de) | 1985-07-25 |
| DE2510669A1 (de) | 1976-09-16 |
| DK157809B (da) | 1990-02-19 |
| FR2303793A1 (fr) | 1976-10-08 |
| GB1542958A (en) | 1979-03-28 |
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