JPS6011030B2 - アルコキシアルキル１，４−ジヒドロピリジンエステルまたはその塩の製造方法 - Google Patents

アルコキシアルキル１，４−ジヒドロピリジンエステルまたはその塩の製造方法

Info

Publication number
JPS6011030B2
JPS6011030B2 JP49078370A JP7837074A JPS6011030B2 JP S6011030 B2 JPS6011030 B2 JP S6011030B2 JP 49078370 A JP49078370 A JP 49078370A JP 7837074 A JP7837074 A JP 7837074A JP S6011030 B2 JPS6011030 B2 JP S6011030B2
Authority
JP
Japan
Prior art keywords
ester
acid
general formula
group
ethyl ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP49078370A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5040578A (nl
Inventor
ボツザ−ト フリ−ドリツヒ
ベヒンガ− エグバ−ト
フア−タ− ブルフ
ステペル クルト
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of JPS5040578A publication Critical patent/JPS5040578A/ja
Publication of JPS6011030B2 publication Critical patent/JPS6011030B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
JP49078370A 1973-07-12 1974-07-10 アルコキシアルキル１，４−ジヒドロピリジンエステルまたはその塩の製造方法 Expired JPS6011030B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2335466.7 1973-07-12
DE19732335466 DE2335466A1 (de) 1973-07-12 1973-07-12 Alkoxyalkyl-1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
JPS5040578A JPS5040578A (nl) 1975-04-14
JPS6011030B2 true JPS6011030B2 (ja) 1985-03-22

Family

ID=5886689

Family Applications (3)

Application Number Title Priority Date Filing Date
JP49078370A Expired JPS6011030B2 (ja) 1973-07-12 1974-07-10 アルコキシアルキル１，４−ジヒドロピリジンエステルまたはその塩の製造方法
JP57000455A Expired JPS5943952B2 (ja) 1973-07-12 1982-01-06 アルコキシアルキル−１，４−ジヒドロピリジンエステルまたはその塩の製造方法
JP57000454A Expired JPS5943951B2 (ja) 1973-07-12 1982-01-06 アルコキシアルキル−１，４−ジヒドロピリジンエステルまたはその塩の製造法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP57000455A Expired JPS5943952B2 (ja) 1973-07-12 1982-01-06 アルコキシアルキル−１，４−ジヒドロピリジンエステルまたはその塩の製造方法
JP57000454A Expired JPS5943951B2 (ja) 1973-07-12 1982-01-06 アルコキシアルキル−１，４−ジヒドロピリジンエステルまたはその塩の製造法

Country Status (21)

Country Link
JP (3) JPS6011030B2 (nl)
AT (1) AT337699B (nl)
AU (1) AU477107B2 (nl)
BE (1) BE817540A (nl)
CA (1) CA1025450A (nl)
CH (2) CH614196A5 (nl)
DD (1) DD118631A5 (nl)
DE (1) DE2335466A1 (nl)
DK (1) DK373974A (nl)
ES (5) ES428185A1 (nl)
FI (1) FI212074A (nl)
FR (1) FR2236497B1 (nl)
GB (1) GB1436289A (nl)
HU (1) HU171401B (nl)
IE (1) IE39602B1 (nl)
IL (1) IL45233A (nl)
LU (1) LU70498A1 (nl)
NL (1) NL7409344A (nl)
PL (2) PL91873B1 (nl)
SE (1) SE7409146L (nl)
ZA (1) ZA744461B (nl)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552911A (en) * 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof
GB1591089A (en) * 1976-12-17 1981-06-10 Fujisawa Pharmaceutical Co 1,4-dihydropyridine derivatives and process for preparation thereof
JPS53146941U (nl) * 1977-04-26 1978-11-18
DE3222367A1 (de) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung
DE3312283A1 (de) * 1983-04-05 1984-10-18 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern
DE3312216A1 (de) * 1983-04-05 1984-10-11 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von symmetrischen 1,4-dihydropyridincarbonsaeureestern
DE3432563A1 (de) * 1984-09-05 1986-03-13 Bayer Ag, 5090 Leverkusen Neue pyridylethyl-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimittel
GB8428552D0 (en) * 1984-11-12 1984-12-19 Sandoz Ltd Organic compounds
US4678796A (en) * 1984-11-30 1987-07-07 Warner-Lambert Company 2-alkylidene derivatives of 1,2,3,4-tetrahydropyridine-2,5-pyridine carboxylic acid dialkyl esters useful for treatment of cardiovascular disorders
FI862343A (fi) 1985-06-17 1986-12-18 Warner Lambert Co Foerfarande foer framstaellning av terapeutiskt verkande 1,4-dihydropyridinfoereningar.
US4732898A (en) * 1986-04-29 1988-03-22 Warner-Lambert Company 2-(2-aryl-2-oxoalkylidene) analogs of-3,5-pyridinedicarboxylic acid dialkyl esters useful for treatment of cardiovascular disorders
JPS6378289A (ja) * 1986-09-20 1988-04-08 株式会社富士通ゼネラル 車両の台数検出装置
AT399873B (de) * 1988-03-08 1995-08-25 Egyt Gyogyszervegyeszeti Gyar Verfahren zur herstellung eines 1,4-dihydro-pyridin-derivates
GR1002248B (en) * 1988-03-08 1996-04-23 Egyt Gyogyszervegyeszeti Gyar 1,4-dihydropyridine derivatives preparation method
AT399872B (de) * 1988-03-08 1995-08-25 Egyt Gyogyszervegyeszeti Gyar Verfahren zur herstellung eines 1,4-dihydro-pyridin-derivates
AT400241B (de) * 1988-03-08 1995-11-27 Egyt Gyogyszervegyeszeti Gyar Verfahren zur herstellung eines 1,4-dihydro-pyridin-derivates
FR2672890A1 (fr) * 1991-02-20 1992-08-21 Inst Investigacion Desarrol Derives de 2,6-dimethyl-4-(4'-hydroxy-3',5'-di-t-butylphenyl)-1,4-dihydropyridine, leur procede de preparation et leur utilisation comme capteurs de radicaux libres.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1923990C3 (de) * 1969-05-10 1978-11-23 Bayer Ag Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern

Also Published As

Publication number Publication date
JPS5943951B2 (ja) 1984-10-25
JPS57131764A (en) 1982-08-14
AT337699B (de) 1977-07-11
CA1025450A (en) 1978-01-31
FR2236497B1 (nl) 1978-07-21
FR2236497A1 (nl) 1975-02-07
ES448394A1 (es) 1977-07-16
ATA569674A (de) 1976-11-15
AU7096974A (en) 1976-01-08
ES448397A1 (es) 1977-08-01
JPS5040578A (nl) 1975-04-14
DK373974A (nl) 1975-03-03
CH614196A5 (en) 1979-11-15
ZA744461B (en) 1975-07-30
HU171401B (hu) 1978-01-28
ES448395A1 (es) 1977-09-16
JPS57131763A (en) 1982-08-14
LU70498A1 (nl) 1975-03-27
DD118631A5 (nl) 1976-03-12
PL94266B1 (nl) 1977-07-30
IL45233A (en) 1978-06-15
DE2335466A1 (de) 1975-01-30
IL45233A0 (en) 1974-10-22
JPS5943952B2 (ja) 1984-10-25
NL7409344A (nl) 1975-01-14
ES448396A1 (es) 1977-09-16
AU477107B2 (en) 1976-10-14
IE39602B1 (en) 1978-11-22
IE39602L (en) 1975-01-12
CH622507A5 (en) 1981-04-15
GB1436289A (en) 1976-05-19
BE817540A (fr) 1975-01-13
FI212074A (nl) 1975-01-13
ES428185A1 (es) 1976-12-16
PL91873B1 (nl) 1977-03-31
SE7409146L (sv) 1975-01-13

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