JPS5987036A - 微小カプセルの製造方法 - Google Patents
微小カプセルの製造方法Info
- Publication number
- JPS5987036A JPS5987036A JP57196036A JP19603682A JPS5987036A JP S5987036 A JPS5987036 A JP S5987036A JP 57196036 A JP57196036 A JP 57196036A JP 19603682 A JP19603682 A JP 19603682A JP S5987036 A JPS5987036 A JP S5987036A
- Authority
- JP
- Japan
- Prior art keywords
- emulsifying
- particle size
- spindle
- liquid
- oil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003094 microcapsule Substances 0.000 title claims abstract description 31
- 238000002360 preparation method Methods 0.000 title description 3
- 239000007788 liquid Substances 0.000 claims abstract description 48
- 239000002775 capsule Substances 0.000 claims abstract description 33
- 229920000642 polymer Polymers 0.000 claims abstract description 10
- 239000000178 monomer Substances 0.000 claims abstract description 9
- IVJISJACKSSFGE-UHFFFAOYSA-N formaldehyde;1,3,5-triazine-2,4,6-triamine Chemical compound O=C.NC1=NC(N)=NC(N)=N1 IVJISJACKSSFGE-UHFFFAOYSA-N 0.000 claims abstract description 6
- 229920005989 resin Polymers 0.000 claims abstract description 6
- 239000011347 resin Substances 0.000 claims abstract description 6
- 238000004519 manufacturing process Methods 0.000 claims description 25
- 239000011148 porous material Substances 0.000 claims description 10
- 239000007764 o/w emulsion Substances 0.000 claims description 8
- 230000015572 biosynthetic process Effects 0.000 claims description 5
- 239000008267 milk Substances 0.000 claims 1
- 210000004080 milk Anatomy 0.000 claims 1
- 235000013336 milk Nutrition 0.000 claims 1
- 230000001804 emulsifying effect Effects 0.000 abstract description 55
- 239000002245 particle Substances 0.000 abstract description 47
- 238000009826 distribution Methods 0.000 abstract description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 9
- 239000000839 emulsion Substances 0.000 abstract description 8
- 238000010008 shearing Methods 0.000 abstract description 7
- 239000000203 mixture Substances 0.000 abstract description 2
- 229920000877 Melamine resin Polymers 0.000 abstract 1
- 229920001807 Urea-formaldehyde Polymers 0.000 abstract 1
- ODGAOXROABLFNM-UHFFFAOYSA-N polynoxylin Chemical compound O=C.NC(N)=O ODGAOXROABLFNM-UHFFFAOYSA-N 0.000 abstract 1
- 238000004945 emulsification Methods 0.000 description 27
- 238000000034 method Methods 0.000 description 26
- 239000000243 solution Substances 0.000 description 12
- 230000004087 circulation Effects 0.000 description 10
- 238000011161 development Methods 0.000 description 8
- 238000012545 processing Methods 0.000 description 5
- 239000000126 substance Substances 0.000 description 5
- 229920003169 water-soluble polymer Polymers 0.000 description 5
- 239000006185 dispersion Substances 0.000 description 4
- 239000000975 dye Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000003995 emulsifying agent Substances 0.000 description 4
- GHMLBKRAJCXXBS-UHFFFAOYSA-N resorcinol Chemical compound OC1=CC=CC(O)=C1 GHMLBKRAJCXXBS-UHFFFAOYSA-N 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- 108010010803 Gelatin Proteins 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 239000007864 aqueous solution Substances 0.000 description 3
- 238000007796 conventional method Methods 0.000 description 3
- 229920001577 copolymer Polymers 0.000 description 3
- 239000011162 core material Substances 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 239000008273 gelatin Substances 0.000 description 3
- 229920000159 gelatin Polymers 0.000 description 3
- 235000019322 gelatine Nutrition 0.000 description 3
- 235000011852 gelatine desserts Nutrition 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000012695 Interfacial polymerization Methods 0.000 description 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
- 239000004202 carbamide Substances 0.000 description 2
- 238000005354 coacervation Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000005538 encapsulation Methods 0.000 description 2
- 238000011065 in-situ storage Methods 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 238000010025 steaming Methods 0.000 description 2
- LIZLYZVAYZQVPG-UHFFFAOYSA-N (3-bromo-2-fluorophenyl)methanol Chemical compound OCC1=CC=CC(Br)=C1F LIZLYZVAYZQVPG-UHFFFAOYSA-N 0.000 description 1
- AGBXYHCHUYARJY-UHFFFAOYSA-N 2-phenylethenesulfonic acid Chemical compound OS(=O)(=O)C=CC1=CC=CC=C1 AGBXYHCHUYARJY-UHFFFAOYSA-N 0.000 description 1
- 235000011293 Brassica napus Nutrition 0.000 description 1
- 240000008100 Brassica rapa Species 0.000 description 1
- 235000000540 Brassica rapa subsp rapa Nutrition 0.000 description 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 description 1
- 239000005977 Ethylene Substances 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- ZKURGBYDCVNWKH-UHFFFAOYSA-N [3,7-bis(dimethylamino)phenothiazin-10-yl]-phenylmethanone Chemical compound C12=CC=C(N(C)C)C=C2SC2=CC(N(C)C)=CC=C2N1C(=O)C1=CC=CC=C1 ZKURGBYDCVNWKH-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000003905 agrochemical Substances 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 238000006482 condensation reaction Methods 0.000 description 1
- 239000002612 dispersion medium Substances 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000004880 explosion Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 239000000446 fuel Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 238000010030 laminating Methods 0.000 description 1
- 239000004973 liquid crystal related substance Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 210000005087 mononuclear cell Anatomy 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000003348 petrochemical agent Substances 0.000 description 1
- 238000005191 phase separation Methods 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000002685 polymerization catalyst Substances 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 229920006264 polyurethane film Polymers 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/06—Making microcapsules or microballoons by phase separation
- B01J13/14—Polymerisation; cross-linking
- B01J13/18—In situ polymerisation with all reactants being present in the same phase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Color Printing (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57196036A JPS5987036A (ja) | 1982-11-10 | 1982-11-10 | 微小カプセルの製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57196036A JPS5987036A (ja) | 1982-11-10 | 1982-11-10 | 微小カプセルの製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5987036A true JPS5987036A (ja) | 1984-05-19 |
| JPH0366013B2 JPH0366013B2 (OSRAM) | 1991-10-15 |
Family
ID=16351130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP57196036A Granted JPS5987036A (ja) | 1982-11-10 | 1982-11-10 | 微小カプセルの製造方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5987036A (OSRAM) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4619904A (en) * | 1984-10-29 | 1986-10-28 | General Electric Company | Agglutinating immunoassay using protein-coated liquid droplets |
| US4634681A (en) * | 1984-10-29 | 1987-01-06 | General Electric Company | Diagnostic method of determining the presence or absence of select proteins in a liquid sample |
| JPH02160579A (ja) * | 1988-12-14 | 1990-06-20 | Fuji Photo Film Co Ltd | 感圧記録シート用マイクロカプセル |
| JPH03501940A (ja) * | 1987-09-28 | 1991-05-09 | レッデング・ジュニア，ブルース・ケイ | マイクロカプセル調製のための装置および方法 |
| US5194188A (en) * | 1989-07-05 | 1993-03-16 | Patrinove | Process and a device for the direct production of liposomes |
| US5558820A (en) * | 1991-02-13 | 1996-09-24 | Fuji Photo Film Co., Ltd. | Process for preparing microcapsules |
-
1982
- 1982-11-10 JP JP57196036A patent/JPS5987036A/ja active Granted
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4619904A (en) * | 1984-10-29 | 1986-10-28 | General Electric Company | Agglutinating immunoassay using protein-coated liquid droplets |
| US4634681A (en) * | 1984-10-29 | 1987-01-06 | General Electric Company | Diagnostic method of determining the presence or absence of select proteins in a liquid sample |
| JPH03501940A (ja) * | 1987-09-28 | 1991-05-09 | レッデング・ジュニア，ブルース・ケイ | マイクロカプセル調製のための装置および方法 |
| JPH02160579A (ja) * | 1988-12-14 | 1990-06-20 | Fuji Photo Film Co Ltd | 感圧記録シート用マイクロカプセル |
| US5194188A (en) * | 1989-07-05 | 1993-03-16 | Patrinove | Process and a device for the direct production of liposomes |
| US5558820A (en) * | 1991-02-13 | 1996-09-24 | Fuji Photo Film Co., Ltd. | Process for preparing microcapsules |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0366013B2 (OSRAM) | 1991-10-15 |
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