JPS59225152A - α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステル又はその塩酸塩の製法 - Google Patents

α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステル又はその塩酸塩の製法

Info

Publication number
JPS59225152A
JPS59225152A JP58098716A JP9871683A JPS59225152A JP S59225152 A JPS59225152 A JP S59225152A JP 58098716 A JP58098716 A JP 58098716A JP 9871683 A JP9871683 A JP 9871683A JP S59225152 A JPS59225152 A JP S59225152A
Authority
JP
Japan
Prior art keywords
methyl ester
aspartyl
hydrochloride
phenylalanine
apm
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP58098716A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0441155B2 (xx
Inventor
Yoichi Ozawa
小沢　洋一
Shinichi Kishimoto
岸本　信一
Emiko Shinohara
篠原　恵美子
Tadashi Takemoto
正 竹本
Arahiko Eguchi
江口　新比古
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP58098716A priority Critical patent/JPS59225152A/ja
Priority to US06/611,548 priority patent/US4618695A/en
Priority to EP84303418A priority patent/EP0127977B1/en
Priority to DE8484303418T priority patent/DE3467352D1/de
Priority to IE1258/84A priority patent/IE57518B1/en
Priority to CA000455147A priority patent/CA1268598A/en
Priority to KR1019840003049A priority patent/KR920002337B1/ko
Publication of JPS59225152A publication Critical patent/JPS59225152A/ja
Priority to KR1019920001929A priority patent/KR920003333B1/ko
Publication of JPH0441155B2 publication Critical patent/JPH0441155B2/ja
Granted legal-status Critical Current

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  • Peptides Or Proteins (AREA)
JP58098716A 1983-06-02 1983-06-02 α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステル又はその塩酸塩の製法 Granted JPS59225152A (ja)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP58098716A JPS59225152A (ja) 1983-06-02 1983-06-02 α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステル又はその塩酸塩の製法
US06/611,548 US4618695A (en) 1983-06-02 1984-05-17 Method of preparing methyl ester and its hydrochloride
EP84303418A EP0127977B1 (en) 1983-06-02 1984-05-21 Method of preparing alpha-l-aspartyl-l-phenylalanine methyl ester and its hydrochloride
DE8484303418T DE3467352D1 (en) 1983-06-02 1984-05-21 Method of preparing alpha-l-aspartyl-l-phenylalanine methyl ester and its hydrochloride
IE1258/84A IE57518B1 (en) 1983-06-02 1984-05-21 Method of preparing alpha-l-aspartyl-l-phenylalanine methyl ester and its hydrochloride
CA000455147A CA1268598A (en) 1983-06-02 1984-05-25 METHOD OF PREPARING .alpha.-L-ASPARTYL-L-PHENYLALANINE METHYL ESTER AND ITS HYDROCHLORIDE
KR1019840003049A KR920002337B1 (ko) 1983-06-02 1984-06-01 α-L-아스파르틸-L-페닐알라닌 메틸 에스테르 및 이의 염산염의 제조방법
KR1019920001929A KR920003333B1 (ko) 1983-06-02 1992-02-11 α-L-아스파르틸-L-페닐알라닌 β-저급 알킬 에스테르의 제조방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58098716A JPS59225152A (ja) 1983-06-02 1983-06-02 α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステル又はその塩酸塩の製法

Publications (2)

Publication Number Publication Date
JPS59225152A true JPS59225152A (ja) 1984-12-18
JPH0441155B2 JPH0441155B2 (xx) 1992-07-07

Family

ID=14227241

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58098716A Granted JPS59225152A (ja) 1983-06-02 1983-06-02 α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステル又はその塩酸塩の製法

Country Status (1)

Country Link
JP (1) JPS59225152A (xx)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4745210A (en) * 1984-12-17 1988-05-17 Mitsui Toatsu Chemicals, Incorporated Preparation process of N-formyl-α-aspartyl phenylalanine
US4778916A (en) * 1985-03-26 1988-10-18 Mitsui Toatsu Chemicals, Inc. Preparation process of α-L-aspartyl-L-phenylalanine methyl ester or hydrochloride thereof
US4801732A (en) * 1984-12-27 1989-01-31 Mitsui Toatsu Chemicals, Incorporated Preparation process of α-L-aspartyl-L-phenylalanine methyl ester
US4918216A (en) * 1986-12-05 1990-04-17 Mitsui Toatsu Chemicals, Incorporated Preparation process of α-l-aspartyl-l-phenyl-alanine methyl ester or hydrohalide thereof
US4962222A (en) * 1986-12-19 1990-10-09 Mitsui Toatsu Chemicals, Incorporated Preparation process of α-l-aspartyl-l-phenylalanine methyl ester having low hygroscopicity
JP2005058212A (ja) * 2003-01-24 2005-03-10 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フェニルアラニン−β−エステルの製造方法およびα−Ｌ−アスパルチル−Ｌ−フェニルアラニン−α−メチルエステルの製造方法
EP1587941A4 (en) * 2003-01-24 2006-06-21 Ajinomoto Kk PROCESS FOR PRODUCING (A) -L-ASPARTYL-L-PHENYLALANINE- (B) -ESTER AND PROCESS FOR PRODUCING (A) -L-ASPARTYL-L-PHENYLALANINE- (A) -METHYL ESTER
JP2010029213A (ja) * 2002-07-26 2010-02-12 Ajinomoto Co Inc 新規ペプチド生成酵素遺伝子

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5071642A (xx) * 1973-11-05 1975-06-13
JPS5382752A (en) * 1976-12-27 1978-07-21 Monsanto Co Improved method of preparing alphaa aspartyl l phenylalanin methyl ester

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5071642A (xx) * 1973-11-05 1975-06-13
JPS5382752A (en) * 1976-12-27 1978-07-21 Monsanto Co Improved method of preparing alphaa aspartyl l phenylalanin methyl ester

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4745210A (en) * 1984-12-17 1988-05-17 Mitsui Toatsu Chemicals, Incorporated Preparation process of N-formyl-α-aspartyl phenylalanine
US4801732A (en) * 1984-12-27 1989-01-31 Mitsui Toatsu Chemicals, Incorporated Preparation process of α-L-aspartyl-L-phenylalanine methyl ester
US4778916A (en) * 1985-03-26 1988-10-18 Mitsui Toatsu Chemicals, Inc. Preparation process of α-L-aspartyl-L-phenylalanine methyl ester or hydrochloride thereof
US4918216A (en) * 1986-12-05 1990-04-17 Mitsui Toatsu Chemicals, Incorporated Preparation process of α-l-aspartyl-l-phenyl-alanine methyl ester or hydrohalide thereof
US4962222A (en) * 1986-12-19 1990-10-09 Mitsui Toatsu Chemicals, Incorporated Preparation process of α-l-aspartyl-l-phenylalanine methyl ester having low hygroscopicity
JP2010029213A (ja) * 2002-07-26 2010-02-12 Ajinomoto Co Inc 新規ペプチド生成酵素遺伝子
JP2010029214A (ja) * 2002-07-26 2010-02-12 Ajinomoto Co Inc 新規ペプチド生成酵素遺伝子
EP1587941A4 (en) * 2003-01-24 2006-06-21 Ajinomoto Kk PROCESS FOR PRODUCING (A) -L-ASPARTYL-L-PHENYLALANINE- (B) -ESTER AND PROCESS FOR PRODUCING (A) -L-ASPARTYL-L-PHENYLALANINE- (A) -METHYL ESTER
JP2005058212A (ja) * 2003-01-24 2005-03-10 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フェニルアラニン−β−エステルの製造方法およびα−Ｌ−アスパルチル−Ｌ−フェニルアラニン−α−メチルエステルの製造方法
EP2157188A1 (en) * 2003-01-24 2010-02-24 Ajinomoto Co., Inc. Method for producing alpha-L-Aspartyl-L-phenylalanine-Beta-ester and method for producing alpha-L-aspartyl-L-phenylalanine-alpha-methyl ester
EP2166109A1 (en) * 2003-01-24 2010-03-24 Ajinomoto Co., Inc. Method for producing alpha-L-aspartyl-L-phenylalanine-beta-ester and method for producing alpha-L-aspartyl-L-phenylalanine-alpha-methyl ester
EP2180059A1 (en) * 2003-01-24 2010-04-28 Ajinomoto Co., Inc. Method for producing alpha-L-aspartyl-L-phenylalanine-beta-ester and method for producing alpha-L-aspartyl-L-phenylalanine-alpha-methyl ester
EP2180060A1 (en) * 2003-01-24 2010-04-28 Ajinomoto Co., Inc. Method for produding alpha-L-aspartyl-L-phenylalanine-beta-ester and method for producing alpha-L-aspartyl-L-phenylalanine-alpha-methyl ester
EP2180061A1 (en) * 2003-01-24 2010-04-28 Ajinomoto Co., Inc. Method for producing alpha-L-aspartyl-L-phenylalanine-beta-ester and method for producing alpha-L-aspartyl-L-phenylalanine-alpha-methyl ester

Also Published As

Publication number Publication date
JPH0441155B2 (xx) 1992-07-07

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