JPS59163374A - トリアゾ−ル抗真菌剤 - Google Patents

トリアゾ−ル抗真菌剤

Info

Publication number
JPS59163374A
JPS59163374A JP59027972A JP2797284A JPS59163374A JP S59163374 A JPS59163374 A JP S59163374A JP 59027972 A JP59027972 A JP 59027972A JP 2797284 A JP2797284 A JP 2797284A JP S59163374 A JPS59163374 A JP S59163374A
Authority
JP
Japan
Prior art keywords
group
compound
formula
mixture
fluorophenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP59027972A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6366835B2 (https=
Inventor
ケネス・リチヤ−ドソン
ピ−タ−・ジヨン・ホウイツトル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp SRL
Original Assignee
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp SRL filed Critical Pfizer Corp SRL
Publication of JPS59163374A publication Critical patent/JPS59163374A/ja
Publication of JPS6366835B2 publication Critical patent/JPS6366835B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/713—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with four or more nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
JP59027972A 1983-02-16 1984-02-16 トリアゾ−ル抗真菌剤 Granted JPS59163374A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB8304282 1983-02-16
GB838304282A GB8304282D0 (en) 1983-02-16 1983-02-16 Antifungal agents
GB8317446 1983-06-28

Publications (2)

Publication Number Publication Date
JPS59163374A true JPS59163374A (ja) 1984-09-14
JPS6366835B2 JPS6366835B2 (https=) 1988-12-22

Family

ID=10538079

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59027972A Granted JPS59163374A (ja) 1983-02-16 1984-02-16 トリアゾ−ル抗真菌剤

Country Status (3)

Country Link
US (1) US4616026A (https=)
JP (1) JPS59163374A (https=)
GB (1) GB8304282D0 (https=)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02104583A (ja) * 1988-08-13 1990-04-17 Pfizer Inc トリアゾール抗真菌剤
EP0780380A1 (en) * 1995-12-22 1997-06-25 Ss Pharmaceutical Co., Ltd. Triazole derivatives with antimycotic action and intermediates
JP2000344744A (ja) * 1999-06-04 2000-12-12 Ss Pharmaceut Co Ltd アセトフェノン誘導体およびその製法
JP2013525375A (ja) * 2010-04-24 2013-06-20 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 金属酵素阻害化合物
JP2014517068A (ja) * 2011-06-19 2014-07-17 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 金属酵素阻害剤化合物
JP2014517044A (ja) * 2011-06-19 2014-07-17 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 金属酵素阻害化合物
JP2014517069A (ja) * 2011-06-23 2014-07-17 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 金属酵素化合物
JP2015504095A (ja) * 2012-01-20 2015-02-05 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 金属酵素阻害薬化合物
US9655363B2 (en) 2013-02-04 2017-05-23 Syngenta Participations Ag Microbiocides
JP2017110004A (ja) * 2012-01-20 2017-06-22 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 金属酵素阻害剤化合物
US11051514B2 (en) 2015-05-18 2021-07-06 Mycovia Pharmaceuticals, Inc. Antifungal compounds

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2558834B1 (fr) * 1984-01-26 1988-01-08 Rhone Poulenc Agrochimie Fongicides a groupes triazole et oligoether
EP0194064A3 (en) * 1985-03-06 1988-11-17 Imperial Chemical Industries Plc Azolyl substituted aralkyl compounds
JP3471831B2 (ja) * 1991-12-09 2003-12-02 富山化学工業株式会社 新規なトリアゾール誘導体およびその塩
US6002028A (en) * 1995-12-22 1999-12-14 Ss Pharmaceutical Co., Ltd. Triazole derivative, preparation process thereof and pharmaceutical comprising the same as an effective ingredient
EP2051964A4 (en) * 2006-07-28 2012-03-07 Univ Connecticut INHIBITORS OF FATTY ACID AMIDHYDROLASE
IN2014MN01378A (https=) 2011-12-11 2015-07-03 Viamet Pharmaceuticals Inc
US20150246898A1 (en) * 2012-09-12 2015-09-03 Dow Agrosciences Llc Metalloenzyme inhibitor compounds
CA2909213A1 (en) 2013-04-12 2014-10-16 Bayer Cropscience Aktiengesellschaft Novel triazole derivatives
CN108289457B (zh) 2015-09-18 2021-08-06 迈科维亚医药公司 抗真菌化合物制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE45765B1 (en) * 1976-08-19 1982-11-17 Ici Ltd Triazoles and imidazoles useful as plant fungicides and growth regulating agents
DE2832234A1 (de) * 1978-07-21 1980-01-31 Bayer Ag Alpha -azolyl-keto-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide
US4654332A (en) * 1979-03-07 1987-03-31 Imperial Chemical Industries Plc Heterocyclic compounds
DE2951164A1 (de) * 1979-12-19 1981-07-16 Bayer Ag, 5090 Leverkusen Substituierte triazolylmethyl-tert.-butyl-ketone, verfahren zu ihrer herstellung und ihre verwendung als pflanzenschutzmittel sowie als zwischenprodukte
NZ198085A (en) * 1980-08-18 1985-09-13 Ici Plc Regulation of plant growth with certain 2,2-di(hydrocarbyl)-1-(1,2,4-triazol-1-yl)ethan-2-ols
AU553482B2 (en) * 1980-08-28 1986-07-17 Imperial Chemical Industries Plc Pharmaceutical compositions of fungicidal triazole derivatives
EP0069442B1 (en) * 1981-06-06 1985-02-20 Pfizer Limited Antifungal agents, processes for their preparation, and pharmaceutical compositions containing them
US4483863A (en) * 1984-01-20 1984-11-20 Pfizer Inc. Triazole antifungal agents

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02104583A (ja) * 1988-08-13 1990-04-17 Pfizer Inc トリアゾール抗真菌剤
EP0780380A1 (en) * 1995-12-22 1997-06-25 Ss Pharmaceutical Co., Ltd. Triazole derivatives with antimycotic action and intermediates
JP2000344744A (ja) * 1999-06-04 2000-12-12 Ss Pharmaceut Co Ltd アセトフェノン誘導体およびその製法
JP2013525375A (ja) * 2010-04-24 2013-06-20 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 金属酵素阻害化合物
JP2017132766A (ja) * 2011-06-19 2017-08-03 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 金属酵素阻害剤化合物
US9556143B2 (en) 2011-06-19 2017-01-31 Viamet Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
JP2014517068A (ja) * 2011-06-19 2014-07-17 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 金属酵素阻害剤化合物
JP2014518220A (ja) * 2011-06-19 2014-07-28 ヴィアメット ファーマスーティカルズ，インコーポレイテッド メタロ酵素阻害剤化合物
JP2014518219A (ja) * 2011-06-19 2014-07-28 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 金属酵素阻害剤化合物
JP2014517044A (ja) * 2011-06-19 2014-07-17 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 金属酵素阻害化合物
JP2014523880A (ja) * 2011-06-23 2014-09-18 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 金属酵素化合物
JP2017101027A (ja) * 2011-06-23 2017-06-08 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 金属酵素化合物
JP2014517069A (ja) * 2011-06-23 2014-07-17 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 金属酵素化合物
JP2015504095A (ja) * 2012-01-20 2015-02-05 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 金属酵素阻害薬化合物
JP2017110004A (ja) * 2012-01-20 2017-06-22 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 金属酵素阻害剤化合物
US10221160B2 (en) 2012-01-20 2019-03-05 Mycovia Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
US10526312B2 (en) 2012-01-20 2020-01-07 Mycovia Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
US11247981B2 (en) 2012-01-20 2022-02-15 Mycovia Pharmaceuticals, Inc. Metalloenzyme inhibitor compounds
US9655363B2 (en) 2013-02-04 2017-05-23 Syngenta Participations Ag Microbiocides
US11051514B2 (en) 2015-05-18 2021-07-06 Mycovia Pharmaceuticals, Inc. Antifungal compounds

Also Published As

Publication number Publication date
JPS6366835B2 (https=) 1988-12-22
GB8304282D0 (en) 1983-03-23
US4616026A (en) 1986-10-07

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