JPS5915636B2 - 安定なオキシダ−ゼ試薬溶液 - Google Patents
安定なオキシダ−ゼ試薬溶液Info
- Publication number
- JPS5915636B2 JPS5915636B2 JP51141752A JP14175276A JPS5915636B2 JP S5915636 B2 JPS5915636 B2 JP S5915636B2 JP 51141752 A JP51141752 A JP 51141752A JP 14175276 A JP14175276 A JP 14175276A JP S5915636 B2 JPS5915636 B2 JP S5915636B2
- Authority
- JP
- Japan
- Prior art keywords
- reagent solution
- oxidase
- stable
- acid
- neisseria
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003153 chemical reaction reagent Substances 0.000 title claims description 24
- 102000004316 Oxidoreductases Human genes 0.000 title claims description 20
- 108090000854 Oxidoreductases Proteins 0.000 title claims description 20
- 150000003839 salts Chemical class 0.000 claims description 13
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims description 10
- 229910052757 nitrogen Inorganic materials 0.000 claims description 5
- BZORFPDSXLZWJF-UHFFFAOYSA-N N,N-dimethyl-1,4-phenylenediamine Chemical compound CN(C)C1=CC=C(N)C=C1 BZORFPDSXLZWJF-UHFFFAOYSA-N 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 2
- 238000001514 detection method Methods 0.000 claims description 2
- 230000000813 microbial effect Effects 0.000 claims description 2
- 150000004985 diamines Chemical class 0.000 claims 4
- CBCKQZAAMUWICA-UHFFFAOYSA-N 1,4-phenylenediamine Chemical compound NC1=CC=C(N)C=C1 CBCKQZAAMUWICA-UHFFFAOYSA-N 0.000 claims 1
- CJAOGUFAAWZWNI-UHFFFAOYSA-N 1-n,1-n,4-n,4-n-tetramethylbenzene-1,4-diamine Chemical compound CN(C)C1=CC=C(N(C)C)C=C1 CJAOGUFAAWZWNI-UHFFFAOYSA-N 0.000 claims 1
- 239000000243 solution Substances 0.000 description 16
- 241000588653 Neisseria Species 0.000 description 11
- 238000012360 testing method Methods 0.000 description 8
- 239000002609 medium Substances 0.000 description 7
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 239000002585 base Substances 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 150000007522 mineralic acids Chemical class 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 150000007524 organic acids Chemical class 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- 102000000634 Cytochrome c oxidase subunit IV Human genes 0.000 description 2
- 108050008072 Cytochrome c oxidase subunit IV Proteins 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 2
- 238000000855 fermentation Methods 0.000 description 2
- 230000004151 fermentation Effects 0.000 description 2
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000012299 nitrogen atmosphere Substances 0.000 description 2
- 150000004986 phenylenediamines Chemical class 0.000 description 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 2
- BMYNFMYTOJXKLE-UHFFFAOYSA-N 3-azaniumyl-2-hydroxypropanoate Chemical compound NCC(O)C(O)=O BMYNFMYTOJXKLE-UHFFFAOYSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 239000005711 Benzoic acid Substances 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 201000009906 Meningitis Diseases 0.000 description 1
- KWYHDKDOAIKMQN-UHFFFAOYSA-N N,N,N',N'-tetramethylethylenediamine Chemical compound CN(C)CCN(C)C KWYHDKDOAIKMQN-UHFFFAOYSA-N 0.000 description 1
- 241000588652 Neisseria gonorrhoeae Species 0.000 description 1
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 description 1
- 235000021314 Palmitic acid Nutrition 0.000 description 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 235000011054 acetic acid Nutrition 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 235000010233 benzoic acid Nutrition 0.000 description 1
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 235000015165 citric acid Nutrition 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- -1 diamine salt Chemical class 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000012458 free base Substances 0.000 description 1
- 239000001530 fumaric acid Substances 0.000 description 1
- 235000011087 fumaric acid Nutrition 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000006799 invasive growth in response to glucose limitation Effects 0.000 description 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
- 239000011976 maleic acid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- 229910017604 nitric acid Inorganic materials 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000006152 selective media Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000007655 standard test method Methods 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 125000003698 tetramethyl group Chemical group [H]C([H])([H])* 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/871—Neisseria
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/643,465 US4017420A (en) | 1975-12-22 | 1975-12-22 | Stable oxidase reagent solutions |
| US000000643465 | 1975-12-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5282777A JPS5282777A (en) | 1977-07-11 |
| JPS5915636B2 true JPS5915636B2 (ja) | 1984-04-10 |
Family
ID=24580942
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51141752A Expired JPS5915636B2 (ja) | 1975-12-22 | 1976-11-24 | 安定なオキシダ−ゼ試薬溶液 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4017420A (Direct) |
| JP (1) | JPS5915636B2 (Direct) |
| AT (1) | AT350734B (Direct) |
| AU (1) | AU507640B2 (Direct) |
| BE (1) | BE848697A (Direct) |
| BR (1) | BR7608015A (Direct) |
| CA (1) | CA1069030A (Direct) |
| CH (1) | CH624144A5 (Direct) |
| DE (1) | DE2653821C2 (Direct) |
| ES (1) | ES453758A1 (Direct) |
| FI (1) | FI55521C (Direct) |
| FR (1) | FR2336481A1 (Direct) |
| GB (1) | GB1565675A (Direct) |
| IT (1) | IT1064494B (Direct) |
| LU (1) | LU76437A1 (Direct) |
| NL (1) | NL7613092A (Direct) |
| NO (1) | NO145846C (Direct) |
| SE (1) | SE422080B (Direct) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4372874A (en) * | 1976-09-13 | 1983-02-08 | Modrovich Ivan Endre | Stabilization of hydrolysis prone labile organic reagents in liquid media |
| DE2716060C3 (de) * | 1977-04-09 | 1980-06-12 | Boehringer Mannheim Gmbh, 6800 Mannheim | Stabilisierte Schnelldiagnostica mit Oxydationsindikatoren |
| DE3114935C2 (de) * | 1981-04-13 | 1983-12-22 | Schöbel, Barbara, Dr., 6220 Rüdesheim | Verfahren zur Bestimmung von Wasserstoffperoxid |
| DE3480720D1 (de) * | 1983-05-16 | 1990-01-18 | Nabisco Brands Inc | Verfahren zum unterscheiden von glukose-2-oxydase produzierenden mikroorganismen. |
| US7909895B2 (en) * | 2004-11-10 | 2011-03-22 | Enertech Environmental, Inc. | Slurry dewatering and conversion of biosolids to a renewable fuel |
| CA2606319A1 (en) | 2005-04-27 | 2006-11-09 | Enertech Environmental, Inc. | Organic waste disposal facility and method of disposal |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2970945A (en) * | 1958-10-03 | 1961-02-07 | Miles Lab | Diagnostic composition |
| US3876503A (en) * | 1971-10-29 | 1975-04-08 | Frederick C Mennen | Method and instrument for the detection of neisseria gonorrheae without culture |
-
1975
- 1975-12-22 US US05/643,465 patent/US4017420A/en not_active Expired - Lifetime
-
1976
- 1976-11-16 GB GB47720/76A patent/GB1565675A/en not_active Expired
- 1976-11-22 SE SE7613025A patent/SE422080B/xx not_active IP Right Cessation
- 1976-11-23 CA CA266,344A patent/CA1069030A/en not_active Expired
- 1976-11-23 AU AU19919/76A patent/AU507640B2/en not_active Expired
- 1976-11-24 BE BE172654A patent/BE848697A/xx not_active IP Right Cessation
- 1976-11-24 NL NL7613092A patent/NL7613092A/xx not_active Application Discontinuation
- 1976-11-24 FI FI763377A patent/FI55521C/fi not_active IP Right Cessation
- 1976-11-24 JP JP51141752A patent/JPS5915636B2/ja not_active Expired
- 1976-11-25 IT IT29779/76A patent/IT1064494B/it active
- 1976-11-25 AT AT875876A patent/AT350734B/de not_active IP Right Cessation
- 1976-11-25 NO NO764026A patent/NO145846C/no unknown
- 1976-11-26 CH CH1493676A patent/CH624144A5/de not_active IP Right Cessation
- 1976-11-26 DE DE2653821A patent/DE2653821C2/de not_active Expired
- 1976-11-29 ES ES453758A patent/ES453758A1/es not_active Expired
- 1976-11-29 FR FR7635929A patent/FR2336481A1/fr active Granted
- 1976-11-30 BR BR7608015A patent/BR7608015A/pt unknown
- 1976-12-20 LU LU76437A patent/LU76437A1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE848697A (fr) | 1977-05-24 |
| JPS5282777A (en) | 1977-07-11 |
| FR2336481A1 (fr) | 1977-07-22 |
| NO145846B (no) | 1982-03-01 |
| FI55521B (fi) | 1979-04-30 |
| DE2653821A1 (de) | 1977-06-30 |
| US4017420A (en) | 1977-04-12 |
| NL7613092A (nl) | 1977-06-24 |
| CA1069030A (en) | 1980-01-01 |
| ES453758A1 (es) | 1977-11-01 |
| AU1991976A (en) | 1978-06-01 |
| NO764026L (Direct) | 1977-06-23 |
| FI763377A7 (Direct) | 1977-06-23 |
| SE7613025L (sv) | 1977-06-23 |
| IT1064494B (it) | 1985-02-18 |
| AT350734B (de) | 1979-06-11 |
| FI55521C (fi) | 1979-08-10 |
| ATA875876A (de) | 1978-11-15 |
| DE2653821C2 (de) | 1986-04-17 |
| LU76437A1 (Direct) | 1977-06-10 |
| AU507640B2 (en) | 1980-02-21 |
| GB1565675A (en) | 1980-04-23 |
| SE422080B (sv) | 1982-02-15 |
| NO145846C (no) | 1982-06-09 |
| CH624144A5 (Direct) | 1981-07-15 |
| FR2336481B1 (Direct) | 1979-03-09 |
| BR7608015A (pt) | 1977-11-08 |
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