JPS5892680A - パ−フルオロビシクロ化合物 - Google Patents

パ−フルオロビシクロ化合物

Info

Publication number
JPS5892680A
JPS5892680A JP56191358A JP19135881A JPS5892680A JP S5892680 A JPS5892680 A JP S5892680A JP 56191358 A JP56191358 A JP 56191358A JP 19135881 A JP19135881 A JP 19135881A JP S5892680 A JPS5892680 A JP S5892680A
Authority
JP
Japan
Prior art keywords
compound
formulai
compound shown
ring
fluorination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56191358A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6358834B2 (OSRAM
Inventor
Kazumasa Yokoyama
和正 横山
Tsutomu Fukaya
深谷　力
Yoshio Tsuda
良夫 津田
Taizo Ono
泰蔵 小野
Yoshio Arakawa
荒川　良夫
Tadakazu Suyama
須山　忠和
Ryoichi Naito
内藤　良一
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
GC Biopharma Corp
Original Assignee
Green Cross Corp Japan
Green Cross Corp Korea
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Green Cross Corp Japan, Green Cross Corp Korea filed Critical Green Cross Corp Japan
Priority to JP56191358A priority Critical patent/JPS5892680A/ja
Priority to US06/454,108 priority patent/US4526969A/en
Publication of JPS5892680A publication Critical patent/JPS5892680A/ja
Priority to US06/670,971 priority patent/US4591599A/en
Priority to US06/670,969 priority patent/US4599343A/en
Priority to US06/670,970 priority patent/US4596810A/en
Publication of JPS6358834B2 publication Critical patent/JPS6358834B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/01—Products
    • C25B3/05—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/01—Products
    • C25B3/09—Nitrogen containing compounds
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/01—Products
    • C25B3/11—Halogen containing compounds
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B3/00—Electrolytic production of organic compounds
    • C25B3/20—Processes
    • C25B3/27—Halogenation
    • C25B3/28—Fluorination

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Metallurgy (AREA)
  • Materials Engineering (AREA)
  • Electrochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
JP56191358A 1981-11-27 1981-11-27 パ−フルオロビシクロ化合物 Granted JPS5892680A (ja)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP56191358A JPS5892680A (ja) 1981-11-27 1981-11-27 パ−フルオロビシクロ化合物
US06/454,108 US4526969A (en) 1981-11-27 1982-12-28 Trifluoromethyl substituted perfluoro quinolizines
US06/670,971 US4591599A (en) 1981-11-27 1984-11-13 Perfluoropyrrolizines and emulsions thereof useful as blood substitutes
US06/670,969 US4599343A (en) 1981-11-27 1984-11-13 Perfluoroindolizines and emulsions thereof useful as blood substitutes
US06/670,970 US4596810A (en) 1981-11-27 1984-11-13 Emulsions of perfluoro octahydro quinolizines useful as blood substitutes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56191358A JPS5892680A (ja) 1981-11-27 1981-11-27 パ−フルオロビシクロ化合物

Publications (2)

Publication Number Publication Date
JPS5892680A true JPS5892680A (ja) 1983-06-02
JPS6358834B2 JPS6358834B2 (OSRAM) 1988-11-17

Family

ID=16273240

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56191358A Granted JPS5892680A (ja) 1981-11-27 1981-11-27 パ−フルオロビシクロ化合物

Country Status (2)

Country Link
US (1) US4526969A (OSRAM)
JP (1) JPS5892680A (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5243044A (en) * 1986-08-25 1993-09-07 International Therapeutics, Inc. Compounds of perfluoro[3,3,3]propellene and perfluoro hexamethylenetetramine

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4596810A (en) * 1981-11-27 1986-06-24 The Green Cross Corporation Emulsions of perfluoro octahydro quinolizines useful as blood substitutes
JPS58170782A (ja) * 1982-01-22 1983-10-07 アイ・エス・シ−・ケミカルズ・リミテツド 過弗素化複素環式化合物およびこれを含むエマルシヨン
DE3366683D1 (de) * 1982-08-07 1986-11-13 Green Cross Corp Perfluoro-1-azatricyclic amine compound
US5684050A (en) * 1986-01-24 1997-11-04 Hemagen/Pfc Stable emulsions of highly fluorinated organic compounds
US5514720A (en) * 1986-07-09 1996-05-07 Hemagen/Pfc Stable emulsions of highly fluorinated organic compounds
US5171755A (en) * 1988-04-29 1992-12-15 Hemagen/Pfc Emulsions of highly fluorinated organic compounds
US5403575A (en) * 1991-12-12 1995-04-04 Hemagen/Pfc Highly fluorinated, chloro-substituted organic compound-containing emulsions and methods of using them

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5243044A (en) * 1986-08-25 1993-09-07 International Therapeutics, Inc. Compounds of perfluoro[3,3,3]propellene and perfluoro hexamethylenetetramine
US5434191A (en) * 1986-08-25 1995-07-18 International Therapeutics Inc. Artificial blood containing perfluoro chemicals in presence of emulsifying agents

Also Published As

Publication number Publication date
JPS6358834B2 (OSRAM) 1988-11-17
US4526969A (en) 1985-07-02

Similar Documents

Publication Publication Date Title
JPH08512095A (ja) ペルフルオロアルカンスルホニルフルオリドの製造方法
CA1181011A (en) Perfluorinated n,n-dimethyl cyclohexylmethylamine and emulsions containing the same
EP0080716B1 (en) Perfluoro compound and emulsion thereof
JPS6358834B2 (OSRAM)
US4534978A (en) Perfluorocycloamines
CA1219258A (en) Perfluoro-1-azatricyclic amine compound
JPS59112936A (ja) ペルフルオロエ−テル化合物及びその製造法
CA1216289A (en) Perfluorotricyclic amine compound
JPH0144183B2 (OSRAM)
JPH0157108B2 (OSRAM)
SE453392B (sv) Perfluorobicyklo-foreningar och emulsionspreparat med syreberande formaga som innehaller foreningen
JPH0393721A (ja) 水性エマルジョン中のエマルジョン安定化添加剤、血液代用剤水性エマルジョン、過弗化ヘテロ二環化合物及びその製法
SE442634B (sv) Perfluorcykloaminer och emulsionspreparat med syreberande formaga
JPH0216297B2 (OSRAM)
US4599343A (en) Perfluoroindolizines and emulsions thereof useful as blood substitutes
US4591599A (en) Perfluoropyrrolizines and emulsions thereof useful as blood substitutes
JPS5951284A (ja) パ−フルオロ環状アミン化合物
JPS642580B2 (OSRAM)
CA1189079A (en) Perfluorotricyclic amine compounds
JPS591484A (ja) パ−フルオロ環状アミン化合物
JPS5927893A (ja) パ−フルオロ三員環アミン化合物
JPS6360025B2 (OSRAM)
JPS595187A (ja) パ−フルオロ環状アミン化合物
JPS591485A (ja) パ−フルオロ環状アミン化合物
US4596810A (en) Emulsions of perfluoro octahydro quinolizines useful as blood substitutes