JPS5888374A - ベンゾフラノン化合物および該化合物を含む医薬製剤 - Google Patents

ベンゾフラノン化合物および該化合物を含む医薬製剤

Info

Publication number
JPS5888374A
JPS5888374A JP57191736A JP19173682A JPS5888374A JP S5888374 A JPS5888374 A JP S5888374A JP 57191736 A JP57191736 A JP 57191736A JP 19173682 A JP19173682 A JP 19173682A JP S5888374 A JPS5888374 A JP S5888374A
Authority
JP
Japan
Prior art keywords
group
compound
general formula
formula
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP57191736A
Other languages
English (en)
Japanese (ja)
Inventor
パウル・ベンク
ベルナ−・ブライテンシユタイン
マルクス・バウマン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of JPS5888374A publication Critical patent/JPS5888374A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP57191736A 1981-10-28 1982-10-28 ベンゾフラノン化合物および該化合物を含む医薬製剤 Pending JPS5888374A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH6881/811 1981-10-28
CH688181 1981-10-28

Publications (1)

Publication Number Publication Date
JPS5888374A true JPS5888374A (ja) 1983-05-26

Family

ID=4316522

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57191736A Pending JPS5888374A (ja) 1981-10-28 1982-10-28 ベンゾフラノン化合物および該化合物を含む医薬製剤

Country Status (15)

Country Link
US (1) US4514415A (enExample)
EP (1) EP0078240A3 (enExample)
JP (1) JPS5888374A (enExample)
AU (1) AU8982282A (enExample)
DD (1) DD206376A5 (enExample)
DK (1) DK475882A (enExample)
ES (3) ES516841A0 (enExample)
FI (1) FI823639L (enExample)
GB (1) GB2110664B (enExample)
GR (1) GR77708B (enExample)
IL (1) IL67063A0 (enExample)
NO (1) NO823587L (enExample)
NZ (1) NZ202298A (enExample)
PT (1) PT75748B (enExample)
ZA (1) ZA827846B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2611713B1 (fr) * 1987-02-27 1990-11-30 Adir Nouveaux derives de l'acide (dihydro-2,3 oxo-2 benzofurannyl-3)-2 acetique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
US4849428A (en) * 1987-11-23 1989-07-18 The Procter & Gamble Company Cyclic anti-inflammatory derivatives of di-tert-butylphenol compounds, compositions and use
ATE79876T1 (de) * 1988-03-16 1992-09-15 Ciba Geigy Ag Thioverbindungen.
GB9024960D0 (en) * 1990-11-16 1991-01-02 Ici Plc Chemical process
FR2686880B1 (fr) * 1992-02-04 1994-05-13 Hoechst Ste Francaise Procede de preparation de la chloro-5 3h-benzofuranone-2 et son application a l'obtention de l'acide chloro-5 hydroxy-2 phenylacetique.
ES2138902B1 (es) * 1997-05-19 2000-09-16 Salvat Lab Sa "5-ariltio-6-sulfonamido-3(2h)-benzofuranonas como inhibidores de la cox-2".
EP1007037A4 (en) 1997-06-26 2004-10-06 Lilly Co Eli ANTITHROMBOTIC AGENTS
WO2001009131A1 (en) * 1999-07-30 2001-02-08 Zenyaku Kogyo Kabushiki Kaisha Azaindolizinone derivatives and cerebral function improvers containing the same as the active ingredient
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
CN102379684B (zh) 2005-04-28 2014-11-19 普罗透斯数字保健公司 药物信息系统
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
EP2398500B1 (en) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
GB201415329D0 (en) 2014-07-21 2014-10-15 Ge Healthcare Bio Sciences Parallel cell processing method and facility

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3424796A (en) * 1965-03-30 1969-01-28 Sandoz Ag Preparation of 4-aminodibenzo(a,d) cycloalken-5-ones
US3615521A (en) * 1968-10-01 1971-10-26 Eastman Kodak Co Photographic compositions and processes-a
DE2160136C3 (de) * 1971-12-03 1975-01-02 International Flavors & Fragrances Inc., New York, N.Y. (V.St.A.) Sonnenschutzmittel
US3862133A (en) * 1973-04-30 1975-01-21 Goodrich Co B F Gamma-lactones of o-hydroxyphenylacetic acids
US4013690A (en) * 1974-02-05 1977-03-22 Sandoz Ltd. Organic compounds
DE2503223A1 (de) * 1974-02-05 1975-08-07 Sandoz Ag Verfahren zur herstellung neuer carbocyclischer verbindungen
JPS5938268B2 (ja) * 1974-03-22 1984-09-14 カンザキセイシ カブシキガイシヤ 新規フタリド化合物の製造法
FI760548A7 (enExample) * 1975-03-12 1976-09-13 Sandoz Ag
DE2652034A1 (de) * 1976-11-15 1978-05-24 Basf Ag Lichtschutzmittel
CA1113486A (en) * 1977-04-01 1981-12-01 Alfred Halpern Ultra-violet filtration with certain aminosalicylic acid esters

Also Published As

Publication number Publication date
IL67063A0 (en) 1983-02-23
ZA827846B (en) 1983-08-31
PT75748A (de) 1982-11-01
GB2110664A (en) 1983-06-22
NO823587L (no) 1983-04-29
ES8406461A1 (es) 1984-08-01
ES527515A0 (es) 1986-06-16
ES531103A0 (es) 1985-07-16
FI823639A7 (fi) 1983-04-29
FI823639L (fi) 1983-04-29
NZ202298A (en) 1985-11-08
ES8506686A1 (es) 1985-07-16
ES8608502A1 (es) 1986-06-16
US4514415A (en) 1985-04-30
GR77708B (enExample) 1984-09-25
FI823639A0 (fi) 1982-10-25
PT75748B (de) 1985-12-03
EP0078240A2 (de) 1983-05-04
ES516841A0 (es) 1984-08-01
EP0078240A3 (de) 1984-03-28
DD206376A5 (de) 1984-01-25
AU8982282A (en) 1983-05-05
DK475882A (da) 1983-04-29
GB2110664B (en) 1985-03-20

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