JPS58501127A - 置換基の１つが複素環基である新規ジ−オルト置換フェノ−ル，それらの製造方法，それらの化合物を含む特に抗−高血圧性剤，薬物および新規合成中間体 - Google Patents

置換基の１つが複素環基である新規ジ−オルト置換フェノ−ル，それらの製造方法，それらの化合物を含む特に抗−高血圧性剤，薬物および新規合成中間体

Info

Publication number
JPS58501127A
JPS58501127A JP57502218A JP50221882A JPS58501127A JP S58501127 A JPS58501127 A JP S58501127A JP 57502218 A JP57502218 A JP 57502218A JP 50221882 A JP50221882 A JP 50221882A JP S58501127 A JPS58501127 A JP S58501127A
Authority
JP
Japan
Prior art keywords
group
imidazolinyl
tert
ether
butyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP57502218A
Other languages
English (en)
Japanese (ja)
Inventor
テユロン・ジヤン−マリ
Original Assignee
カ−ピベン（セントル　ダクテイビト　エ　ドウ　ルシエルシエ　フア−マソテイ−ク　アンドユストリエル　ビオロジ−ク　エ　メデイカル）
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by カ−ピベン（セントル　ダクテイビト　エ　ドウ　ルシエルシエ　フア−マソテイ−ク　アンドユストリエル　ビオロジ−ク　エ　メデイカル） filed Critical カ−ピベン（セントル　ダクテイビト　エ　ドウ　ルシエルシエ　フア−マソテイ−ク　アンドユストリエル　ビオロジ−ク　エ　メデイカル）
Publication of JPS58501127A publication Critical patent/JPS58501127A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/562—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom
    • C07C45/565—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom by reaction with hexamethylene-tetramine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/56—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups
    • C07C47/565—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups all hydroxy groups bound to the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/56—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups
    • C07C47/57—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/04—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP57502218A 1981-07-17 1982-07-19 置換基の１つが複素環基である新規ジ−オルト置換フェノ−ル，それらの製造方法，それらの化合物を含む特に抗−高血圧性剤，薬物および新規合成中間体 Pending JPS58501127A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8114011A FR2509730A1 (fr) 1981-07-17 1981-07-17 Nouveaux phenols o-halogenes et o-substitues par un heterocycle, leur procede de preparation, medicaments les contenant, notamment anti-hypertenseurs, et nouveaux intermediaires de synthese
FR81/14011EDK 1981-07-17

Publications (1)

Publication Number Publication Date
JPS58501127A true JPS58501127A (ja) 1983-07-14

Family

ID=9260633

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57502218A Pending JPS58501127A (ja) 1981-07-17 1982-07-19 置換基の１つが複素環基である新規ジ−オルト置換フェノ−ル，それらの製造方法，それらの化合物を含む特に抗−高血圧性剤，薬物および新規合成中間体

Country Status (7)

Country Link
EP (1) EP0070779A3 (enExample)
JP (1) JPS58501127A (enExample)
AU (1) AU8731682A (enExample)
DK (1) DK119783A (enExample)
FR (1) FR2509730A1 (enExample)
MC (1) MC1517A1 (enExample)
WO (1) WO1983000333A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3332780A1 (de) * 1983-09-10 1985-03-28 Hoechst Ag, 6230 Frankfurt 6-sulfoxyphenolderivate, ihre herstellung und ihre verwendung als cytoprotekiva

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB591683A (en) * 1945-05-02 1947-08-26 Boots Pure Drug Co Ltd Improvements in and relating to the manufacture of heterocyclic compounds
GB614032A (en) * 1946-07-01 1948-12-08 Boots Pure Drug Co Ltd Improvements in the manufacture of heterocyclic compounds
CY786A (en) * 1970-02-12 1976-06-01 American Home Prod Novel imidazoline derivatives
JPS54145631A (en) * 1978-04-05 1979-11-14 Ube Ind Ltd Preparation of 2-cyanophenol derivative
JPS54145632A (en) * 1978-04-05 1979-11-14 Ube Ind Ltd Preparation of 2-cyanophenol derivative
JPS6039349B2 (ja) * 1979-06-20 1985-09-05 宇部興産株式会社 ２−シアノフエノ−ル誘導体の製法

Also Published As

Publication number Publication date
DK119783D0 (da) 1983-03-15
DK119783A (da) 1983-03-15
FR2509730B1 (enExample) 1984-01-06
EP0070779A3 (fr) 1983-06-22
WO1983000333A1 (fr) 1983-02-03
EP0070779A2 (fr) 1983-01-26
MC1517A1 (fr) 1984-02-10
AU8731682A (en) 1983-03-17
FR2509730A1 (fr) 1983-01-21

Similar Documents

Publication Publication Date Title
DE2428858A1 (de) 1,3-disubstituierte 2,4(1h,3h)chinazolin-derivate
DE2559509A1 (de) Benzcyloamidderivate und verfahren zu ihrer herstellung sowie pharmazeutische mittel, worin sie enthalten sind
DD263058A5 (de) Verfahren zur herstellung von 4-benzyl-1-(2h)-phthalazinon-derivaten
JPS5982374A (ja) ジヒドロキシ−２（１ｈ）キナゾリノン−１−アルカン酸類
EP0709383B1 (fr) Dérivés de la diosmétine, leur procédé de préparation et les compositions pharmaceutiques les contenant
DD272648A5 (de) Chromon-derivate
JPS632977A (ja) 抗高血圧症ジヒドロピリジン誘導体
JPH0453846B2 (enExample)
JPS58501127A (ja) 置換基の１つが複素環基である新規ジ−オルト置換フェノ−ル，それらの製造方法，それらの化合物を含む特に抗−高血圧性剤，薬物および新規合成中間体
JPS58159492A (ja) コリナンテイン誘導体、その製造方法およびその用途
JPS5980668A (ja) Ｎ−アリル化オキサゾリジン−２−オンの光学活性な誘導体、該誘導体の製法及び該誘導体による薬剤
EP0089894A1 (fr) (Benzimidazolyl-1)-1,N-((hydroxy-4 méthoxy-3 phényl)-2 hydroxy-2 éthyl) amino-3 butane et ses sels et hydrates à activité bêta-adrénergique, leurs applications thérapeutiques, et procédé pour les préparer
DE1643198C3 (enExample)
Hanford et al. The structure of vasicine. II. Synthesis of desoxyvasicine
ULLYOT et al. Analgesics. I. Aminophthalidylalkanes
WO1984000957A1 (fr) Derives d'acide 4-amino-tetrahydro-2-naphtoique
DE1212549B (de) Verfahren zur Herstellung von blutdrucksenkendem 1-[Pyrimidinyl-(2)]-guanazol
DE2253914B2 (de) Chromon-3-acrylsaeuren, verfahren zu ihrer herstellung sowie diese verbindung enthaltende arzneimittel
JPH11507331A (ja) ４，４−（二置換）シクロヘキサン−１−オール類モノマーおよび関連化合物
JPH0637447B2 (ja) 新規アミド化合物
JPS6222989B2 (enExample)
JPS6345667B2 (enExample)
JPS58154573A (ja) アルキレンジオキシベンゼン誘導体及びその酸付加塩
JPH0819061B2 (ja) アミノアルコ−ル類
JP3145364B2 (ja) 新規化合物及び該化合物を含有する医薬組成物