JPS577466A - Preparation of indole derivative - Google Patents
Preparation of indole derivativeInfo
- Publication number
- JPS577466A JPS577466A JP8134080A JP8134080A JPS577466A JP S577466 A JPS577466 A JP S577466A JP 8134080 A JP8134080 A JP 8134080A JP 8134080 A JP8134080 A JP 8134080A JP S577466 A JPS577466 A JP S577466A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- reacting
- formula
- alkyl
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Indole Compounds (AREA)
Abstract
PURPOSE: To obtain the titled substance economically, by reacting an oxazolidinone derivative with a compound obtained by reacting a substituted formamide with a halogenating agent, as raw materials, and reducing and hydrolyzing the resultant product in the presence of a base.
CONSTITUTION: A compound of formula I (R is alkyl) is reacted with a compound of formula II (X and Y may be the same or different and alkyl, aryl or aralkyl respectively), preferably in a solvent, e.g. dimethyl sulfoxide, and the resultant product is then reduced and hydrolyzed in the presenc of a base, e.g. sodium hydroxide, preferably in a solvent, to close the ring, cleave the oxazolidinone ring and give a compound of formula III. Preferably, a reaction product obtained by reacting dimethylformamide with phosphorus oxychloride or thionyl chloride is used without isolation.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8134080A JPS577466A (en) | 1980-06-18 | 1980-06-18 | Preparation of indole derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8134080A JPS577466A (en) | 1980-06-18 | 1980-06-18 | Preparation of indole derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS577466A true JPS577466A (en) | 1982-01-14 |
JPS632258B2 JPS632258B2 (en) | 1988-01-18 |
Family
ID=13743634
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP8134080A Granted JPS577466A (en) | 1980-06-18 | 1980-06-18 | Preparation of indole derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS577466A (en) |
-
1980
- 1980-06-18 JP JP8134080A patent/JPS577466A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS632258B2 (en) | 1988-01-18 |
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