JPS572291A - Penem-3-carboxylic derivative and its preparation - Google Patents
Penem-3-carboxylic derivative and its preparationInfo
- Publication number
- JPS572291A JPS572291A JP7612880A JP7612880A JPS572291A JP S572291 A JPS572291 A JP S572291A JP 7612880 A JP7612880 A JP 7612880A JP 7612880 A JP7612880 A JP 7612880A JP S572291 A JPS572291 A JP S572291A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- protecting group
- lower alkyl
- amino
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- OMJQZKZKYZYTAD-BAFYGKSASA-N (5r)-3-(1-aminopropan-2-ylsulfanyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid Chemical compound S1C(SC(CN)C)=C(C(O)=O)N2C(=O)C[C@H]21 OMJQZKZKYZYTAD-BAFYGKSASA-N 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 244000052616 bacterial pathogen Species 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- -1 phosphonio Chemical group 0.000 abstract 1
- 125000001476 phosphono group Chemical group [H]OP(*)(=O)O[H] 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/568—Four-membered rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7612880A JPS572291A (en) | 1980-06-06 | 1980-06-06 | Penem-3-carboxylic derivative and its preparation |
US06/271,010 US4395418A (en) | 1980-06-06 | 1981-06-05 | Penem-3-carboxylic acid derivatives |
FR8111191A FR2483924A1 (fr) | 1980-06-06 | 1981-06-05 | Derives d'acide peneme-3-carboxylique, leurs procedes de preparation et leur application en therapeutique |
ES502828A ES502828A0 (es) | 1980-06-06 | 1981-06-05 | Un procedimiento para la preparacion de derivados del acido penen-3-carboxilico. |
NL8102736A NL8102736A (nl) | 1980-06-06 | 1981-06-05 | Penem-3-carbonzuurverbindingen en hun bereiding. |
CH3723/81A CH651037A5 (de) | 1980-06-06 | 1981-06-05 | Penem-3-carbonsaeurederivate und verfahren zu deren herstellung. |
DE19813122523 DE3122523A1 (de) | 1980-06-06 | 1981-06-05 | Penem-3-carbonsaeurederivate, verfahren zu deren herstellung und diese enthaltende arzneimittel |
GB8117447A GB2078220B (en) | 1980-06-06 | 1981-06-08 | Penem-3-carboxylic acid derivatives and their preparation |
IT67783/81A IT1144602B (it) | 1980-06-06 | 1981-06-08 | Derivati dell acido penicil 3 carbossilico e procedimento per la loro preparazione |
BE0/205047A BE889151A (fr) | 1980-06-06 | 1981-06-09 | Derives d'acides peneme-3-carboxylique, leurs procedes de preparation et leur application en therapeutique |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7612880A JPS572291A (en) | 1980-06-06 | 1980-06-06 | Penem-3-carboxylic derivative and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS572291A true JPS572291A (en) | 1982-01-07 |
JPH0224832B2 JPH0224832B2 (fr) | 1990-05-30 |
Family
ID=13596288
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP7612880A Granted JPS572291A (en) | 1980-06-06 | 1980-06-06 | Penem-3-carboxylic derivative and its preparation |
Country Status (2)
Country | Link |
---|---|
JP (1) | JPS572291A (fr) |
BE (1) | BE889151A (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61180766A (ja) * | 1985-01-14 | 1986-08-13 | フアーミタリア・カルロ・エルバ・ソシエタ・ペル・アツイオーニ | アゼチジノン中間体の製造方法 |
JPH05310759A (ja) * | 1983-01-25 | 1993-11-22 | Merck & Co Inc | 2−アルキルチオペン−2−エム−3−カルボキシル酸抗生物質製造中間体 |
-
1980
- 1980-06-06 JP JP7612880A patent/JPS572291A/ja active Granted
-
1981
- 1981-06-09 BE BE0/205047A patent/BE889151A/fr not_active IP Right Cessation
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05310759A (ja) * | 1983-01-25 | 1993-11-22 | Merck & Co Inc | 2−アルキルチオペン−2−エム−3−カルボキシル酸抗生物質製造中間体 |
JPS61180766A (ja) * | 1985-01-14 | 1986-08-13 | フアーミタリア・カルロ・エルバ・ソシエタ・ペル・アツイオーニ | アゼチジノン中間体の製造方法 |
Also Published As
Publication number | Publication date |
---|---|
BE889151A (fr) | 1981-12-09 |
JPH0224832B2 (fr) | 1990-05-30 |
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