JPS57185276A - Dihydro-dum-4 and dihydro-isodum-4 and their derivative - Google Patents
Dihydro-dum-4 and dihydro-isodum-4 and their derivativeInfo
- Publication number
- JPS57185276A JPS57185276A JP56070497A JP7049781A JPS57185276A JP S57185276 A JPS57185276 A JP S57185276A JP 56070497 A JP56070497 A JP 56070497A JP 7049781 A JP7049781 A JP 7049781A JP S57185276 A JPS57185276 A JP S57185276A
- Authority
- JP
- Japan
- Prior art keywords
- dum
- dihydro
- salts
- derivative
- iso
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
- Saccharide Compounds (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56070497A JPS57185276A (en) | 1981-05-11 | 1981-05-11 | Dihydro-dum-4 and dihydro-isodum-4 and their derivative |
US06/375,333 US4451481A (en) | 1981-05-11 | 1982-05-05 | M-4 And IsoM-4 derivatives and compositions containing them |
CA000402618A CA1195330A (en) | 1981-05-11 | 1982-05-10 | M-4 and isom-4 derivatives, their preparation and compositions containing them |
EP82302392A EP0065843B1 (en) | 1981-05-11 | 1982-05-11 | New m-4 and iso m-4 derivatives, their preparation and compositions containing them |
DE8282302392T DE3266326D1 (en) | 1981-05-11 | 1982-05-11 | New m-4 and iso m-4 derivatives, their preparation and compositions containing them |
AT82302392T ATE15671T1 (de) | 1981-05-11 | 1982-05-11 | M-4- und isom-4-derivate, ihre herstellung und diese enthaltende zusammensetzungen. |
US06/590,733 US4866093A (en) | 1981-05-11 | 1984-03-19 | M-4 and iso M-4 derivatives, their preparation and compositions containing them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56070497A JPS57185276A (en) | 1981-05-11 | 1981-05-11 | Dihydro-dum-4 and dihydro-isodum-4 and their derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57185276A true JPS57185276A (en) | 1982-11-15 |
JPH0139412B2 JPH0139412B2 (ja) | 1989-08-21 |
Family
ID=13433214
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56070497A Granted JPS57185276A (en) | 1981-05-11 | 1981-05-11 | Dihydro-dum-4 and dihydro-isodum-4 and their derivative |
Country Status (6)
Country | Link |
---|---|
US (2) | US4451481A (ja) |
EP (1) | EP0065843B1 (ja) |
JP (1) | JPS57185276A (ja) |
AT (1) | ATE15671T1 (ja) |
CA (1) | CA1195330A (ja) |
DE (1) | DE3266326D1 (ja) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5835144A (ja) * | 1981-08-27 | 1983-03-01 | Sankyo Co Ltd | Mb−530b誘導体およびその製造法 |
US5130306A (en) * | 1989-03-13 | 1992-07-14 | Merck & Co., Inc. | 5-Oxygenated HMG-COA reductase inhibitors |
US4937259A (en) * | 1989-06-09 | 1990-06-26 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4342767A (en) * | 1980-01-23 | 1982-08-03 | Merck & Co., Inc. | Hypocholesteremic fermentation products |
US4444784A (en) * | 1980-08-05 | 1984-04-24 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
PT72394B (en) * | 1980-02-04 | 1982-09-06 | Merck & Co Inc | Process for preparing dihydro and tetrahydromevinoline hypocholesterolimics |
JPS56150037A (en) * | 1980-04-22 | 1981-11-20 | Sankyo Co Ltd | Hydronaphthalene compound |
US4420491A (en) * | 1980-05-28 | 1983-12-13 | Merck & Co., Inc. | Hypocholesteremic fermentation products and process of preparation |
MX7065E (es) * | 1980-06-06 | 1987-04-10 | Sankyo Co | Un procedimiento microbiologico para preparar derivados de ml-236b |
-
1981
- 1981-05-11 JP JP56070497A patent/JPS57185276A/ja active Granted
-
1982
- 1982-05-05 US US06/375,333 patent/US4451481A/en not_active Expired - Lifetime
- 1982-05-10 CA CA000402618A patent/CA1195330A/en not_active Expired
- 1982-05-11 EP EP82302392A patent/EP0065843B1/en not_active Expired
- 1982-05-11 DE DE8282302392T patent/DE3266326D1/de not_active Expired
- 1982-05-11 AT AT82302392T patent/ATE15671T1/de not_active IP Right Cessation
-
1984
- 1984-03-19 US US06/590,733 patent/US4866093A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE3266326D1 (en) | 1985-10-24 |
CA1195330A (en) | 1985-10-15 |
US4451481A (en) | 1984-05-29 |
ATE15671T1 (de) | 1985-10-15 |
EP0065843A1 (en) | 1982-12-01 |
JPH0139412B2 (ja) | 1989-08-21 |
EP0065843B1 (en) | 1985-09-18 |
US4866093A (en) | 1989-09-12 |
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