DE3266326D1 - New m-4 and iso m-4 derivatives, their preparation and compositions containing them - Google Patents

New m-4 and iso m-4 derivatives, their preparation and compositions containing them

Info

Publication number
DE3266326D1
DE3266326D1 DE8282302392T DE3266326T DE3266326D1 DE 3266326 D1 DE3266326 D1 DE 3266326D1 DE 8282302392 T DE8282302392 T DE 8282302392T DE 3266326 T DE3266326 T DE 3266326T DE 3266326 D1 DE3266326 D1 DE 3266326D1
Authority
DE
Germany
Prior art keywords
dihydro
new
iso
derivatives
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282302392T
Other languages
English (en)
Inventor
Akira Fermentation Re Terahara
Minoru Analytical And M Tanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of DE3266326D1 publication Critical patent/DE3266326D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
DE8282302392T 1981-05-11 1982-05-11 New m-4 and iso m-4 derivatives, their preparation and compositions containing them Expired DE3266326D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56070497A JPS57185276A (en) 1981-05-11 1981-05-11 Dihydro-dum-4 and dihydro-isodum-4 and their derivative

Publications (1)

Publication Number Publication Date
DE3266326D1 true DE3266326D1 (en) 1985-10-24

Family

ID=13433214

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282302392T Expired DE3266326D1 (en) 1981-05-11 1982-05-11 New m-4 and iso m-4 derivatives, their preparation and compositions containing them

Country Status (6)

Country Link
US (2) US4451481A (de)
EP (1) EP0065843B1 (de)
JP (1) JPS57185276A (de)
AT (1) ATE15671T1 (de)
CA (1) CA1195330A (de)
DE (1) DE3266326D1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5835144A (ja) * 1981-08-27 1983-03-01 Sankyo Co Ltd Ｍｂ−５３０ｂ誘導体およびその製造法
US5130306A (en) * 1989-03-13 1992-07-14 Merck & Co., Inc. 5-Oxygenated HMG-COA reductase inhibitors
US4937259A (en) * 1989-06-09 1990-06-26 Merck & Co., Inc. Antihypercholesterolemic compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4342767A (en) * 1980-01-23 1982-08-03 Merck & Co., Inc. Hypocholesteremic fermentation products
US4444784A (en) * 1980-08-05 1984-04-24 Merck & Co., Inc. Antihypercholesterolemic compounds
PT72394B (en) * 1980-02-04 1982-09-06 Merck & Co Inc Process for preparing dihydro and tetrahydromevinoline hypocholesterolimics
JPS56150037A (en) * 1980-04-22 1981-11-20 Sankyo Co Ltd Hydronaphthalene compound
US4420491A (en) * 1980-05-28 1983-12-13 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
MX7065E (es) * 1980-06-06 1987-04-10 Sankyo Co Un procedimiento microbiologico para preparar derivados de ml-236b

Also Published As

Publication number Publication date
CA1195330A (en) 1985-10-15
US4451481A (en) 1984-05-29
JPS57185276A (en) 1982-11-15
ATE15671T1 (de) 1985-10-15
EP0065843A1 (de) 1982-12-01
JPH0139412B2 (de) 1989-08-21
EP0065843B1 (de) 1985-09-18
US4866093A (en) 1989-09-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: STREHL, P., DIPL.-ING. DIPL.-WIRTSCH.-ING. SCHUEBEL-HOPF, U., DIPL.-CHEM. DR.RER.NAT., PAT.-ANWAELTE, 8000 MUENCHEN