JPS5625161A - Pyridine derivative and its preparation - Google Patents
Pyridine derivative and its preparationInfo
- Publication number
- JPS5625161A JPS5625161A JP10037779A JP10037779A JPS5625161A JP S5625161 A JPS5625161 A JP S5625161A JP 10037779 A JP10037779 A JP 10037779A JP 10037779 A JP10037779 A JP 10037779A JP S5625161 A JPS5625161 A JP S5625161A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- alkyl
- compound
- preparation
- carbon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:Pyridine derivatives of formula I [A is 1W5C alkylene; B, D are single bond, 1W5C alkylene; Z is single bond, ethynylene, formula II (R2 is H, 1W4C alkyl; R3 is H, Br, Cl, 1W4C alkyl; the bond between carbon and carbon is single or double; where the carbon atom linked to R2 connects with B and the one to R3 with D; R is 1W4C alkyl; R1 is H, 1W12C alkyl] or their pharmaceutically permissible salts.
EXAMPLE: (E)-3-[4-(4-Methyl-3-pyridyl)methylphenyl]-2-methylacrylic ethyl ester.
USE: They are used as a remedy for cerebral apoplexy and cardiac infarction because they have actitivity of inhibiting the biosynthesis of thromboxane A2.
PREPARATION: A compound of formula III is subjected to Wittig reaction to produce a compound of formula IV among compounds of formula I and the compound of formula IV is reduced to give a compound of formula V.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10037779A JPS607982B2 (en) | 1979-08-07 | 1979-08-07 | Pyridine derivative |
CA000341817A CA1134828A (en) | 1978-12-28 | 1979-12-13 | Pyridine derivatives |
US06/105,672 US4271170A (en) | 1978-12-28 | 1979-12-20 | Pyridine derivatives |
DE19792951786 DE2951786A1 (en) | 1978-12-28 | 1979-12-21 | PYRIDE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME |
GB7944369A GB2039903B (en) | 1978-12-28 | 1979-12-24 | Pyridine derivatives |
IT51205/79A IT1162425B (en) | 1978-12-28 | 1979-12-27 | PYRIDINE DERIVATIVES, PROCEDURE TO PREPARE THEM AND DRUGS CONTAINING THEM |
CH11475/79A CH647762A5 (en) | 1978-12-28 | 1979-12-27 | PYRIDE DERIVATIVES. |
FR7931936A FR2445319B1 (en) | 1978-12-28 | 1979-12-28 | PYRIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
US06/233,703 US4317828A (en) | 1978-12-28 | 1981-02-12 | Pyridine derivatives |
US06/329,891 US4427682A (en) | 1978-12-28 | 1981-12-11 | Pyridine alkyl benzoic and thenoic acid compounds and their pharmaceutical compositions |
FR8214397A FR2510108B1 (en) | 1978-12-28 | 1982-08-20 | PYRIDINE DERIVATIVES |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10037779A JPS607982B2 (en) | 1979-08-07 | 1979-08-07 | Pyridine derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5625161A true JPS5625161A (en) | 1981-03-10 |
JPS607982B2 JPS607982B2 (en) | 1985-02-28 |
Family
ID=14272327
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10037779A Expired JPS607982B2 (en) | 1978-12-28 | 1979-08-07 | Pyridine derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS607982B2 (en) |
-
1979
- 1979-08-07 JP JP10037779A patent/JPS607982B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS607982B2 (en) | 1985-02-28 |
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