JPS57171974A - Carbostyril derivative - Google Patents
Carbostyril derivativeInfo
- Publication number
- JPS57171974A JPS57171974A JP56057732A JP5773281A JPS57171974A JP S57171974 A JPS57171974 A JP S57171974A JP 56057732 A JP56057732 A JP 56057732A JP 5773281 A JP5773281 A JP 5773281A JP S57171974 A JPS57171974 A JP S57171974A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- halogen
- activity
- phenylalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical class C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 2
- DOINOJNSIIJKCW-UHFFFAOYSA-N 6-(2-piperidin-1-ylacetyl)-3,4-dihydro-1h-quinolin-2-one;hydrochloride Chemical compound Cl.C=1C=C2NC(=O)CCC2=CC=1C(=O)CN1CCCCC1 DOINOJNSIIJKCW-UHFFFAOYSA-N 0.000 abstract 1
- 206010007559 Cardiac failure congestive Diseases 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 230000017531 blood circulation Effects 0.000 abstract 1
- 239000000496 cardiotonic agent Substances 0.000 abstract 1
- 230000008602 contraction Effects 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 208000019622 heart disease Diseases 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 210000004165 myocardium Anatomy 0.000 abstract 1
- 125000005359 phenoxyalkyl group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000009090 positive inotropic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Landscapes
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (25)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56057732A JPS57171974A (en) | 1981-04-15 | 1981-04-15 | Carbostyril derivative |
FI820338A FI77852C (fi) | 1981-02-17 | 1982-02-03 | Foerfarande foer framstaellning av nya, saosom hjaertmediciner anvaendbara substituerade amid- och (maettad heterocykel)karbonylkarbostyrilderivat. |
DE19823204892 DE3204892A1 (de) | 1981-02-17 | 1982-02-12 | Carbostyrilderivate, verfahren zu deren herstellung und kardiotonische zusammensetzungen, welche diese enthalten |
SU823394100A SU1331426A3 (ru) | 1981-02-17 | 1982-02-15 | Способ получени производных карбостирила |
BE0/207321A BE892148A (fr) | 1981-02-17 | 1982-02-15 | Derives de carbostyryle, procede pour leur preparation et composition cardiotonique les contenant |
PH26870A PH18085A (en) | 1981-02-17 | 1982-02-15 | Carbostyril derivatives and cardiotonic compositions containing the same |
MX8210261A MX156153A (es) | 1981-02-17 | 1982-02-15 | Procedimiento para producir derivados de carboestirilo |
AU80528/82A AU530264B2 (en) | 1981-02-17 | 1982-02-16 | Carbostyril derivatives |
NL8200593A NL8200593A (nl) | 1981-02-17 | 1982-02-16 | Carbostyrilderivaten, werkwijze ter bereiding daarvan en cardiotone preparaten, die deze bevatten. |
CA000396327A CA1199915A (en) | 1981-02-17 | 1982-02-16 | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same |
PT74440A PT74440B (en) | 1981-02-17 | 1982-02-16 | Carbostyril derivatives process for producing the same and cardiotonic compositions containing the same |
NO820479A NO159446C (no) | 1981-02-17 | 1982-02-16 | Analogifremgangsmaate for fremstilling av terapeutisk aktive karbostyril-derivater. |
US06/348,709 US4487772A (en) | 1981-02-17 | 1982-02-16 | Carbostyril derivatives and their salts |
FR8202479A FR2512818B1 (fr) | 1981-02-17 | 1982-02-16 | Derives de carbostyryle, procede pour leur preparation et composition cardiotonique les contenant |
DK066582A DK152287C (da) | 1981-02-17 | 1982-02-16 | Analogifremgangsmaade til fremstilling af carbostyril-derivater |
AT0059582A AT386198B (de) | 1981-02-17 | 1982-02-16 | Verfahren zur herstellung von neuen carbostyrilderivaten und von deren pharmazeutisch annehmbaren salzen |
KR8200668A KR860001337B1 (ko) | 1981-02-17 | 1982-02-16 | 카르보스티릴 유도체의 제법 |
SE8200916A SE445348B (sv) | 1981-02-17 | 1982-02-16 | Karbostyrilderivat, forfarande for framstellning derav och hjertsterkande komposition som innehaller detsamma |
GB8204581A GB2094789B (en) | 1981-02-17 | 1982-02-17 | Carbostyril derivatives |
ES509693A ES8305334A1 (es) | 1981-02-17 | 1982-02-17 | Derivados de carbostirilo y sus sales. |
IT67177/82A IT1157002B (it) | 1981-02-17 | 1982-02-17 | Derivati carbostirilici procedimento per la loro produzione e composizioni cardiotoniche contenenti tali derivati |
CH996/82A CH651827A5 (de) | 1981-02-17 | 1982-02-17 | Carbostyrilderivate, verfahren zu ihrer herstellung und kardiotonische zusammensetzungen, welche diese enthalten. |
ES518303A ES518303A0 (es) | 1981-02-17 | 1982-12-16 | Un procedimiento para la produccion de un derivado de carbostirilo. |
US06/525,812 US4454130A (en) | 1981-02-17 | 1983-08-22 | Morpholino and oxazoline substituted carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same |
US06/525,284 US4468402A (en) | 1981-02-17 | 1983-08-22 | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56057732A JPS57171974A (en) | 1981-04-15 | 1981-04-15 | Carbostyril derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57171974A true JPS57171974A (en) | 1982-10-22 |
JPS649313B2 JPS649313B2 (enrdf_load_stackoverflow) | 1989-02-16 |
Family
ID=13064087
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56057732A Granted JPS57171974A (en) | 1981-02-17 | 1981-04-15 | Carbostyril derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57171974A (enrdf_load_stackoverflow) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5829766A (ja) * | 1981-08-12 | 1983-02-22 | Otsuka Pharmaceut Co Ltd | カルボスチリル誘導体 |
JPS58148861A (ja) * | 1982-02-26 | 1983-09-05 | Otsuka Pharmaceut Co Ltd | カルボスチリル誘導体 |
US5591751A (en) * | 1993-02-16 | 1997-01-07 | Otsuka Pharmaceutical Co., Ltd. | Peripheral vasodilators |
US5656642A (en) * | 1993-04-07 | 1997-08-12 | Otsuka Pharmaceutical Co., Ltd. | Peripheral vasodilating agent containing piperidine derivative as active ingredient |
US8445516B2 (en) | 2004-01-29 | 2013-05-21 | Otsuka Pharmaceutical Co., Ltd. | Pharmaceutical composition for promoting angiogenesis |
-
1981
- 1981-04-15 JP JP56057732A patent/JPS57171974A/ja active Granted
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5829766A (ja) * | 1981-08-12 | 1983-02-22 | Otsuka Pharmaceut Co Ltd | カルボスチリル誘導体 |
JPS58148861A (ja) * | 1982-02-26 | 1983-09-05 | Otsuka Pharmaceut Co Ltd | カルボスチリル誘導体 |
US5591751A (en) * | 1993-02-16 | 1997-01-07 | Otsuka Pharmaceutical Co., Ltd. | Peripheral vasodilators |
US5656642A (en) * | 1993-04-07 | 1997-08-12 | Otsuka Pharmaceutical Co., Ltd. | Peripheral vasodilating agent containing piperidine derivative as active ingredient |
US5760058A (en) * | 1993-04-07 | 1998-06-02 | Otsuka Pharmaceutical Co., Ltd. | Peripheral vasodilating agent containing piperidine derivative as active ingredient |
US8445516B2 (en) | 2004-01-29 | 2013-05-21 | Otsuka Pharmaceutical Co., Ltd. | Pharmaceutical composition for promoting angiogenesis |
Also Published As
Publication number | Publication date |
---|---|
JPS649313B2 (enrdf_load_stackoverflow) | 1989-02-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS5777676A (en) | Carbostyril derivative | |
EP0125756A3 (en) | Fused imidazole compounds, processes for the preparation thereof and pharmaceutical compositions containing them | |
JPS57171974A (en) | Carbostyril derivative | |
EP0330939A3 (en) | Acrylic acid morpholides, their production and use | |
JPS57154129A (en) | Cardiotonic drug | |
JPS56103168A (en) | Thiazole derivative, its preparation, and antihistaminic agent containing the same | |
GB1513320A (en) | N-propargyl-2-phenylamino-2-imidazolines | |
ES489327A1 (es) | Procedimiento para la obtencion de derivados de piridina 3- sustituidos de efecto fungicida | |
EG14379A (en) | Triazolyl alkene derivatives,a process for their preparation and their use as fungicides | |
JPS55127371A (en) | Carbostyril derivative | |
JPS5780322A (en) | Cardiotonic agent | |
DE3375917D1 (en) | Thiomethylpyridine derivatives, process for their preparation and medicaments containing them | |
EP0189272A3 (en) | New furanone derivatives, processes for preparation thereof and use thereof | |
JPS5780321A (en) | Cardiotonic agent | |
GB1497729A (en) | Benzenesulphonyl ureas and process for their manufacture | |
JPS57142972A (en) | Carbostyril derivative | |
EP0205299A3 (en) | Isatin derivatives, compositions containing the same, and the use thereof for ulcer diseases | |
HUT43047A (en) | Process for preparing novel 3(2h)-pyridazinone derivatives and pharmaceutical compositions comprising the same | |
JPS5746984A (en) | Theobromine derivative and its preparation | |
JPS5756425A (en) | Hypotensor | |
JPS5651465A (en) | Benzothiazine derivative | |
JPS5726670A (en) | Acrylonitrile derivative | |
EP0089635A3 (en) | Phospholipid derivatives, process for preparation thereof and pharmaceutical composition of the same | |
EP0311051A3 (en) | Pyridylacetonitrile derivatives | |
YU246482A (en) | Process for preparing 1-furyl-3,4-dihydro-isoquinolines |