JPS57159778A - Carbostyril derivative - Google Patents
Carbostyril derivativeInfo
- Publication number
- JPS57159778A JPS57159778A JP4584281A JP4584281A JPS57159778A JP S57159778 A JPS57159778 A JP S57159778A JP 4584281 A JP4584281 A JP 4584281A JP 4584281 A JP4584281 A JP 4584281A JP S57159778 A JPS57159778 A JP S57159778A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- lower alkyl
- preventive
- formula
- carbostyril derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- LISFMEBWQUVKPJ-UHFFFAOYSA-N quinolin-2-ol Chemical class C1=CC=C2NC(=O)C=CC2=C1 LISFMEBWQUVKPJ-UHFFFAOYSA-N 0.000 title 1
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000003449 preventive effect Effects 0.000 abstract 2
- -1 5-[(2-Cyclohexyl-imidazol-1-yl)]-3,4-dihydrocarbostyril Chemical compound 0.000 abstract 1
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- 208000018152 Cerebral disease Diseases 0.000 abstract 1
- 206010008190 Cerebrovascular accident Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 208000032109 Transient ischaemic attack Diseases 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000007514 bases Chemical class 0.000 abstract 1
- 230000000747 cardiac effect Effects 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000000302 ischemic effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- XSXHWVKGUXMUQE-UHFFFAOYSA-N osmium dioxide Inorganic materials O=[Os]=O XSXHWVKGUXMUQE-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 201000010875 transient cerebral ischemia Diseases 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4584281A JPS57159778A (en) | 1981-03-27 | 1981-03-27 | Carbostyril derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4584281A JPS57159778A (en) | 1981-03-27 | 1981-03-27 | Carbostyril derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS57159778A true JPS57159778A (en) | 1982-10-01 |
| JPS6366318B2 JPS6366318B2 (enrdf_load_stackoverflow) | 1988-12-20 |
Family
ID=12730467
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4584281A Granted JPS57159778A (en) | 1981-03-27 | 1981-03-27 | Carbostyril derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57159778A (enrdf_load_stackoverflow) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0240015A2 (en) | 1986-04-02 | 1987-10-07 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives, process for preparing them, pharmaceutical composition, and use |
| JPS6345220A (ja) * | 1986-04-02 | 1988-02-26 | Otsuka Pharmaceut Co Ltd | 血小板粘着抑制剤 |
| US4792561A (en) * | 1986-05-29 | 1988-12-20 | Syntex (U.S.A.) Inc. | Carbostyril derivatives as combined thromboxane synthetase and cyclic-AMP phosphodiesterase inhibitors |
| JPS646271A (en) * | 1986-04-02 | 1989-01-10 | Otsuka Pharma Co Ltd | Carbostyril derivative |
| WO1994026732A1 (en) * | 1993-05-19 | 1994-11-24 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| US5434164A (en) * | 1986-04-02 | 1995-07-18 | Otsuka Pharmaceutical Co. Ltd. | Carbostyril derivatives and salts thereof and pharmaceutical compositions for inhibiting adhesion of thrombocytes |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5430183A (en) * | 1977-08-10 | 1979-03-06 | Otsuka Pharmaceut Co Ltd | 3,4-dihydrocarbostyril derivative |
-
1981
- 1981-03-27 JP JP4584281A patent/JPS57159778A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5430183A (en) * | 1977-08-10 | 1979-03-06 | Otsuka Pharmaceut Co Ltd | 3,4-dihydrocarbostyril derivative |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0240015A2 (en) | 1986-04-02 | 1987-10-07 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives, process for preparing them, pharmaceutical composition, and use |
| JPS6345220A (ja) * | 1986-04-02 | 1988-02-26 | Otsuka Pharmaceut Co Ltd | 血小板粘着抑制剤 |
| JPS646271A (en) * | 1986-04-02 | 1989-01-10 | Otsuka Pharma Co Ltd | Carbostyril derivative |
| US5008274A (en) * | 1986-04-02 | 1991-04-16 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives and salts thereof and pharmaceutical composition for inhibiting adhesion of thrombocytes |
| US5434164A (en) * | 1986-04-02 | 1995-07-18 | Otsuka Pharmaceutical Co. Ltd. | Carbostyril derivatives and salts thereof and pharmaceutical compositions for inhibiting adhesion of thrombocytes |
| US4792561A (en) * | 1986-05-29 | 1988-12-20 | Syntex (U.S.A.) Inc. | Carbostyril derivatives as combined thromboxane synthetase and cyclic-AMP phosphodiesterase inhibitors |
| WO1994026732A1 (en) * | 1993-05-19 | 1994-11-24 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| US5541198A (en) * | 1993-05-19 | 1996-07-30 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6366318B2 (enrdf_load_stackoverflow) | 1988-12-20 |
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