JPS552655A - Quinoline derivative - Google Patents

Quinoline derivative

Info

Publication number
JPS552655A
JPS552655A JP7558978A JP7558978A JPS552655A JP S552655 A JPS552655 A JP S552655A JP 7558978 A JP7558978 A JP 7558978A JP 7558978 A JP7558978 A JP 7558978A JP S552655 A JPS552655 A JP S552655A
Authority
JP
Japan
Prior art keywords
formula
derivative
quinoline
compound
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7558978A
Other languages
Japanese (ja)
Other versions
JPS615476B2 (en
Inventor
Takao Nishi
Takashi Ueda
Kazuyuki Nakagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP7558978A priority Critical patent/JPS552655A/en
Publication of JPS552655A publication Critical patent/JPS552655A/en
Publication of JPS615476B2 publication Critical patent/JPS615476B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Quinoline Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A quinoline derivative of formula I: (R 1 is lower alkyl or phenyl group; R2 and R3 are lower alkyl or cycloalkyl groups), and its acid addition salt.
EXAMPLE: 2-Acetoxy-6-[3-(N-methyl-N-cyclohexylaminocarbonyl)propoxy]quinoline.
USE: Useful as remedies for bronchial asthma, arteriosclerosis, diabetes, and hypertension, and as preventive remedies for thrombosis, having good absorption and prolonged duration.
PROCESS: A carbostyril derivative of formula II is reacted with an acid halide of formula III: (X is halogen) or an acid anhydride of formula IV to give the compound of formula I. The compound of formula II is novel and can be obtained by reacting a carboxyalkoxycarbostyril derivative of formula V with an amine to form an amide linkage.
COPYRIGHT: (C)1980,JPO&Japio
JP7558978A 1978-06-21 1978-06-21 Quinoline derivative Granted JPS552655A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7558978A JPS552655A (en) 1978-06-21 1978-06-21 Quinoline derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7558978A JPS552655A (en) 1978-06-21 1978-06-21 Quinoline derivative

Publications (2)

Publication Number Publication Date
JPS552655A true JPS552655A (en) 1980-01-10
JPS615476B2 JPS615476B2 (en) 1986-02-18

Family

ID=13580531

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7558978A Granted JPS552655A (en) 1978-06-21 1978-06-21 Quinoline derivative

Country Status (1)

Country Link
JP (1) JPS552655A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989010919A1 (en) 1988-05-02 1989-11-16 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989010919A1 (en) 1988-05-02 1989-11-16 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives

Also Published As

Publication number Publication date
JPS615476B2 (en) 1986-02-18

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