JPS57175168A - Carbostyril derivative - Google Patents
Carbostyril derivativeInfo
- Publication number
- JPS57175168A JPS57175168A JP56058831A JP5883181A JPS57175168A JP S57175168 A JPS57175168 A JP S57175168A JP 56058831 A JP56058831 A JP 56058831A JP 5883181 A JP5883181 A JP 5883181A JP S57175168 A JPS57175168 A JP S57175168A
- Authority
- JP
- Japan
- Prior art keywords
- agent
- formula
- cycloalkyl
- compound
- bond
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:The compound of formulaI[R1 is H or alkenyl; R2 is alkanoyloxyalkyl or benzoyloxyalkyl; R3 is cycloalkyl, tetrahydropyranylalkyl, etc.; A is alkylene; R2 and R3 may together with an N atom to which they are attached form the group of formula II (R4 is phenyl, cycloalkyl, etc.; B is methine or N); the bond between the 3- and 4-position carbons is single or double], and its salt.
EXAMPLE: 6-{ 3-[ N-( 2-Acetyloxyethyl )-N-cyclohexylaminocarbonyl ]propoxy} carbostyril.
USE: Preventive and remedy for thrombosis such as cerebral apoplexy, cardiac infarction, etc., agent for improving cerebral circulation, antiphlogistic agent, antiasthmatic acid of agnet, cardiac stimulant, hypotensor, and phosphodiesterase-inhibiting agent.
PROCESS: The compound of formulaIcan be prepared by reacting the carboxylic formula III with the amine of formula V under the conditions of the ordinary amide-bond formation reaction.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56058831A JPS57175168A (en) | 1981-04-17 | 1981-04-17 | Carbostyril derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56058831A JPS57175168A (en) | 1981-04-17 | 1981-04-17 | Carbostyril derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57175168A true JPS57175168A (en) | 1982-10-28 |
Family
ID=13095587
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56058831A Pending JPS57175168A (en) | 1981-04-17 | 1981-04-17 | Carbostyril derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57175168A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62135423A (en) * | 1985-12-09 | 1987-06-18 | Otsuka Pharmaceut Co Ltd | Improver for hypoxia |
WO1989010919A1 (en) | 1988-05-02 | 1989-11-16 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
US5227381A (en) * | 1988-05-02 | 1993-07-13 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivative |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS545981A (en) * | 1977-06-10 | 1979-01-17 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivatives |
JPS54115383A (en) * | 1978-02-28 | 1979-09-07 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
JPS54163825A (en) * | 1978-06-15 | 1979-12-26 | Otsuka Pharma Co Ltd | Phosphoesterase inhibitor |
JPS5579370A (en) * | 1978-12-08 | 1980-06-14 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
JPS572274A (en) * | 1980-06-06 | 1982-01-07 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
JPS5793962A (en) * | 1980-12-01 | 1982-06-11 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
JPS6340429A (en) * | 1986-08-05 | 1988-02-20 | Fujitsu Ltd | Constitution of telephone sounder |
JPS6435827A (en) * | 1987-07-30 | 1989-02-06 | Nec Corp | Display device |
-
1981
- 1981-04-17 JP JP56058831A patent/JPS57175168A/en active Pending
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS545981A (en) * | 1977-06-10 | 1979-01-17 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivatives |
JPS54115383A (en) * | 1978-02-28 | 1979-09-07 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
JPS54163825A (en) * | 1978-06-15 | 1979-12-26 | Otsuka Pharma Co Ltd | Phosphoesterase inhibitor |
JPS5579370A (en) * | 1978-12-08 | 1980-06-14 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
JPS572274A (en) * | 1980-06-06 | 1982-01-07 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
JPS5793962A (en) * | 1980-12-01 | 1982-06-11 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
JPS6340429A (en) * | 1986-08-05 | 1988-02-20 | Fujitsu Ltd | Constitution of telephone sounder |
JPS6435827A (en) * | 1987-07-30 | 1989-02-06 | Nec Corp | Display device |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62135423A (en) * | 1985-12-09 | 1987-06-18 | Otsuka Pharmaceut Co Ltd | Improver for hypoxia |
WO1989010919A1 (en) | 1988-05-02 | 1989-11-16 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
JPH0249768A (en) * | 1988-05-02 | 1990-02-20 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
US5227381A (en) * | 1988-05-02 | 1993-07-13 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivative |
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