JPS57175168A - Carbostyril derivative - Google Patents

Carbostyril derivative

Info

Publication number
JPS57175168A
JPS57175168A JP56058831A JP5883181A JPS57175168A JP S57175168 A JPS57175168 A JP S57175168A JP 56058831 A JP56058831 A JP 56058831A JP 5883181 A JP5883181 A JP 5883181A JP S57175168 A JPS57175168 A JP S57175168A
Authority
JP
Japan
Prior art keywords
agent
formula
cycloalkyl
compound
bond
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56058831A
Other languages
Japanese (ja)
Inventor
Takao Nishi
Tatsuyoshi Tanaka
Kazuyuki Nakagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP56058831A priority Critical patent/JPS57175168A/en
Publication of JPS57175168A publication Critical patent/JPS57175168A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:The compound of formulaI[R1 is H or alkenyl; R2 is alkanoyloxyalkyl or benzoyloxyalkyl; R3 is cycloalkyl, tetrahydropyranylalkyl, etc.; A is alkylene; R2 and R3 may together with an N atom to which they are attached form the group of formula II (R4 is phenyl, cycloalkyl, etc.; B is methine or N); the bond between the 3- and 4-position carbons is single or double], and its salt.
EXAMPLE: 6-{ 3-[ N-( 2-Acetyloxyethyl )-N-cyclohexylaminocarbonyl ]propoxy} carbostyril.
USE: Preventive and remedy for thrombosis such as cerebral apoplexy, cardiac infarction, etc., agent for improving cerebral circulation, antiphlogistic agent, antiasthmatic acid of agnet, cardiac stimulant, hypotensor, and phosphodiesterase-inhibiting agent.
PROCESS: The compound of formulaIcan be prepared by reacting the carboxylic formula III with the amine of formula V under the conditions of the ordinary amide-bond formation reaction.
COPYRIGHT: (C)1982,JPO&Japio
JP56058831A 1981-04-17 1981-04-17 Carbostyril derivative Pending JPS57175168A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56058831A JPS57175168A (en) 1981-04-17 1981-04-17 Carbostyril derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56058831A JPS57175168A (en) 1981-04-17 1981-04-17 Carbostyril derivative

Publications (1)

Publication Number Publication Date
JPS57175168A true JPS57175168A (en) 1982-10-28

Family

ID=13095587

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56058831A Pending JPS57175168A (en) 1981-04-17 1981-04-17 Carbostyril derivative

Country Status (1)

Country Link
JP (1) JPS57175168A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62135423A (en) * 1985-12-09 1987-06-18 Otsuka Pharmaceut Co Ltd Improver for hypoxia
WO1989010919A1 (en) 1988-05-02 1989-11-16 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
US5227381A (en) * 1988-05-02 1993-07-13 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivative

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS545981A (en) * 1977-06-10 1979-01-17 Otsuka Pharmaceut Co Ltd Carbostyryl derivatives
JPS54115383A (en) * 1978-02-28 1979-09-07 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS54163825A (en) * 1978-06-15 1979-12-26 Otsuka Pharma Co Ltd Phosphoesterase inhibitor
JPS5579370A (en) * 1978-12-08 1980-06-14 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS572274A (en) * 1980-06-06 1982-01-07 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS5793962A (en) * 1980-12-01 1982-06-11 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
JPS6340429A (en) * 1986-08-05 1988-02-20 Fujitsu Ltd Constitution of telephone sounder
JPS6435827A (en) * 1987-07-30 1989-02-06 Nec Corp Display device

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS545981A (en) * 1977-06-10 1979-01-17 Otsuka Pharmaceut Co Ltd Carbostyryl derivatives
JPS54115383A (en) * 1978-02-28 1979-09-07 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS54163825A (en) * 1978-06-15 1979-12-26 Otsuka Pharma Co Ltd Phosphoesterase inhibitor
JPS5579370A (en) * 1978-12-08 1980-06-14 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS572274A (en) * 1980-06-06 1982-01-07 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS5793962A (en) * 1980-12-01 1982-06-11 Otsuka Pharmaceut Co Ltd Carbostyryl derivative
JPS6340429A (en) * 1986-08-05 1988-02-20 Fujitsu Ltd Constitution of telephone sounder
JPS6435827A (en) * 1987-07-30 1989-02-06 Nec Corp Display device

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62135423A (en) * 1985-12-09 1987-06-18 Otsuka Pharmaceut Co Ltd Improver for hypoxia
WO1989010919A1 (en) 1988-05-02 1989-11-16 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
JPH0249768A (en) * 1988-05-02 1990-02-20 Otsuka Pharmaceut Co Ltd Carbostyril derivative
US5227381A (en) * 1988-05-02 1993-07-13 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivative

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