JPS5579370A - Carbostyril derivative - Google Patents
Carbostyril derivativeInfo
- Publication number
- JPS5579370A JPS5579370A JP15288078A JP15288078A JPS5579370A JP S5579370 A JPS5579370 A JP S5579370A JP 15288078 A JP15288078 A JP 15288078A JP 15288078 A JP15288078 A JP 15288078A JP S5579370 A JPS5579370 A JP S5579370A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- carbostyril
- derivative
- bond
- carbostyril derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Quinoline Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A carbostyril derivative of formula I: (R1 is hydroxy lower alkyl group; R2 is cycloalkyl group; the bond between the carbon atoms at the 3-and 4-positions of the carbostyril skeleton is single or double bond).
EXAMPLE: 6-[3-[N-(2-Hydroxyethyl)-N-cyclohexylaminocarbonyl] propoxy]-carbostyril.
USE: Preventives and treating agents for thrombosis, drugs for ulcers, or antiphlogistics having improved blood platelet antiagglutinating, phosphodiesterase inhibitory and anti-inflammatory actions.
PROCESS: A carboxypropoxycarbostyril derivative of formula II is reacted with an amine of formula III to give the objective compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15288078A JPS5579370A (en) | 1978-12-08 | 1978-12-08 | Carbostyril derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15288078A JPS5579370A (en) | 1978-12-08 | 1978-12-08 | Carbostyril derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5579370A true JPS5579370A (en) | 1980-06-14 |
JPS6126905B2 JPS6126905B2 (en) | 1986-06-23 |
Family
ID=15550134
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15288078A Granted JPS5579370A (en) | 1978-12-08 | 1978-12-08 | Carbostyril derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5579370A (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57175168A (en) * | 1981-04-17 | 1982-10-28 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
JPS57183761A (en) * | 1981-04-30 | 1982-11-12 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
WO1989010919A1 (en) | 1988-05-02 | 1989-11-16 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
WO1993004042A1 (en) * | 1991-08-23 | 1993-03-04 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivative and platelet agglutination inhibitor |
-
1978
- 1978-12-08 JP JP15288078A patent/JPS5579370A/en active Granted
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57175168A (en) * | 1981-04-17 | 1982-10-28 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
JPS57183761A (en) * | 1981-04-30 | 1982-11-12 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
JPH0114911B2 (en) * | 1981-04-30 | 1989-03-14 | Otsuka Pharma Co Ltd | |
WO1989010919A1 (en) | 1988-05-02 | 1989-11-16 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
JPH0249768A (en) * | 1988-05-02 | 1990-02-20 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
WO1993004042A1 (en) * | 1991-08-23 | 1993-03-04 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivative and platelet agglutination inhibitor |
US5506239A (en) * | 1991-08-23 | 1996-04-09 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivative and platelets aggregation inhibitory agent |
US5658926A (en) * | 1991-08-23 | 1997-08-19 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivative and platelets aggregation inhibitory agent |
Also Published As
Publication number | Publication date |
---|---|
JPS6126905B2 (en) | 1986-06-23 |
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