JPS5579370A - Carbostyril derivative - Google Patents

Carbostyril derivative

Info

Publication number
JPS5579370A
JPS5579370A JP15288078A JP15288078A JPS5579370A JP S5579370 A JPS5579370 A JP S5579370A JP 15288078 A JP15288078 A JP 15288078A JP 15288078 A JP15288078 A JP 15288078A JP S5579370 A JPS5579370 A JP S5579370A
Authority
JP
Japan
Prior art keywords
formula
carbostyril
derivative
bond
carbostyril derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP15288078A
Other languages
Japanese (ja)
Other versions
JPS6126905B2 (en
Inventor
Takao Nishi
Tatsuyoshi Tanaka
Kazuyuki Nakagawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP15288078A priority Critical patent/JPS5579370A/en
Publication of JPS5579370A publication Critical patent/JPS5579370A/en
Publication of JPS6126905B2 publication Critical patent/JPS6126905B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Quinoline Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A carbostyril derivative of formula I: (R1 is hydroxy lower alkyl group; R2 is cycloalkyl group; the bond between the carbon atoms at the 3-and 4-positions of the carbostyril skeleton is single or double bond).
EXAMPLE: 6-[3-[N-(2-Hydroxyethyl)-N-cyclohexylaminocarbonyl] propoxy]-carbostyril.
USE: Preventives and treating agents for thrombosis, drugs for ulcers, or antiphlogistics having improved blood platelet antiagglutinating, phosphodiesterase inhibitory and anti-inflammatory actions.
PROCESS: A carboxypropoxycarbostyril derivative of formula II is reacted with an amine of formula III to give the objective compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
JP15288078A 1978-12-08 1978-12-08 Carbostyril derivative Granted JPS5579370A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP15288078A JPS5579370A (en) 1978-12-08 1978-12-08 Carbostyril derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15288078A JPS5579370A (en) 1978-12-08 1978-12-08 Carbostyril derivative

Publications (2)

Publication Number Publication Date
JPS5579370A true JPS5579370A (en) 1980-06-14
JPS6126905B2 JPS6126905B2 (en) 1986-06-23

Family

ID=15550134

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15288078A Granted JPS5579370A (en) 1978-12-08 1978-12-08 Carbostyril derivative

Country Status (1)

Country Link
JP (1) JPS5579370A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57175168A (en) * 1981-04-17 1982-10-28 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS57183761A (en) * 1981-04-30 1982-11-12 Otsuka Pharmaceut Co Ltd Carbostyril derivative
WO1989010919A1 (en) 1988-05-02 1989-11-16 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
WO1993004042A1 (en) * 1991-08-23 1993-03-04 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivative and platelet agglutination inhibitor

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57175168A (en) * 1981-04-17 1982-10-28 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPS57183761A (en) * 1981-04-30 1982-11-12 Otsuka Pharmaceut Co Ltd Carbostyril derivative
JPH0114911B2 (en) * 1981-04-30 1989-03-14 Otsuka Pharma Co Ltd
WO1989010919A1 (en) 1988-05-02 1989-11-16 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
JPH0249768A (en) * 1988-05-02 1990-02-20 Otsuka Pharmaceut Co Ltd Carbostyril derivative
WO1993004042A1 (en) * 1991-08-23 1993-03-04 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivative and platelet agglutination inhibitor
US5506239A (en) * 1991-08-23 1996-04-09 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivative and platelets aggregation inhibitory agent
US5658926A (en) * 1991-08-23 1997-08-19 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivative and platelets aggregation inhibitory agent

Also Published As

Publication number Publication date
JPS6126905B2 (en) 1986-06-23

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