JPS57142960A - Novel optically active 3-organosulfonyloxycarboxylic acid or its ester, and their preparation - Google Patents

Novel optically active 3-organosulfonyloxycarboxylic acid or its ester, and their preparation

Info

Publication number
JPS57142960A
JPS57142960A JP56029055A JP2905581A JPS57142960A JP S57142960 A JPS57142960 A JP S57142960A JP 56029055 A JP56029055 A JP 56029055A JP 2905581 A JP2905581 A JP 2905581A JP S57142960 A JPS57142960 A JP S57142960A
Authority
JP
Japan
Prior art keywords
ester
compound
acid
optically active
organosulfonyloxycarboxylic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56029055A
Other languages
Japanese (ja)
Other versions
JPS649980B2 (en
Inventor
Masami Shimazaki
Nobuo Nagashima
Kazunori Suga
Takehisa Ohashi
Kiyoshi Watanabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanegafuchi Chemical Industry Co Ltd
Original Assignee
Kanegafuchi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanegafuchi Chemical Industry Co Ltd filed Critical Kanegafuchi Chemical Industry Co Ltd
Priority to JP56029055A priority Critical patent/JPS57142960A/en
Publication of JPS57142960A publication Critical patent/JPS57142960A/en
Publication of JPS649980B2 publication Critical patent/JPS649980B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

NEW MATERIAL:The compound of formulaI(R1 is methyl, ethyl, benzyl or p- methylphenyl; R2 is methyl or ethyl; R3 is H or 1W4C alkyl) and its ester.
EXAMPLE: 3-Mesyloxy-2(S)-methylpropionic acid.
USE: Intermediate for synthesis of pharmaceuticals.
PROCESS: The compound of formulaIand its ester can be prepared by reacting the optically active 3-hydroxy-2-alkylpropionic acid of formula II and its ester with the organic sulfonyl compound of formula III (X is chlorine or N-imidazolyl) in the presence of a base (e.g. triethylamine, pyridine, etc.). The compound of formulaIcan be converted easily to the proline derivative of formula IV which is expected to be an orally administrable remedy for hypertension.
COPYRIGHT: (C)1982,JPO&Japio
JP56029055A 1981-02-28 1981-02-28 Novel optically active 3-organosulfonyloxycarboxylic acid or its ester, and their preparation Granted JPS57142960A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56029055A JPS57142960A (en) 1981-02-28 1981-02-28 Novel optically active 3-organosulfonyloxycarboxylic acid or its ester, and their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56029055A JPS57142960A (en) 1981-02-28 1981-02-28 Novel optically active 3-organosulfonyloxycarboxylic acid or its ester, and their preparation

Publications (2)

Publication Number Publication Date
JPS57142960A true JPS57142960A (en) 1982-09-03
JPS649980B2 JPS649980B2 (en) 1989-02-21

Family

ID=12265682

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56029055A Granted JPS57142960A (en) 1981-02-28 1981-02-28 Novel optically active 3-organosulfonyloxycarboxylic acid or its ester, and their preparation

Country Status (1)

Country Link
JP (1) JPS57142960A (en)

Also Published As

Publication number Publication date
JPS649980B2 (en) 1989-02-21

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