JPS57120599A - Treatment of protein organic solution - Google Patents
Treatment of protein organic solutionInfo
- Publication number
- JPS57120599A JPS57120599A JP763581A JP763581A JPS57120599A JP S57120599 A JPS57120599 A JP S57120599A JP 763581 A JP763581 A JP 763581A JP 763581 A JP763581 A JP 763581A JP S57120599 A JPS57120599 A JP S57120599A
- Authority
- JP
- Japan
- Prior art keywords
- protein
- solution
- molecular weight
- membrane
- polyimide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Peptides Or Proteins (AREA)
Abstract
PURPOSE: A solution of protein is treated with a polyimide semipermeable membrane having a specific chemical structure unit to effect stably the high degree of concentration of the solution, even when the protein is low molecular weight.
CONSTITUTION: An organic solution containing protein, which may contain water, such as a protein acetone solution, is brought into contact with a semipermeable membrane of polyimide polymer having a recurring structural unit of the formula (R is divalent organic group), preferably the imidization rate definited with formula II is 98W100% and the intrinsic viscosity is 0.60W0.85 and average molecular weight is 30,000W80,000, especially, polyimide with a group of formula III (X is divalent group) as a R is preferred. Thus, the protein solution is concentrated, as the membrane works as a semipermeable membrane.
EFFECT: Even when the membrane continues to contact with an organic solvent for hours, its molecular weight fractionation is kept constant and the recovery rate of protein is very high.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP763581A JPS57120599A (en) | 1981-01-20 | 1981-01-20 | Treatment of protein organic solution |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP763581A JPS57120599A (en) | 1981-01-20 | 1981-01-20 | Treatment of protein organic solution |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS57120599A true JPS57120599A (en) | 1982-07-27 |
Family
ID=11671281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP763581A Pending JPS57120599A (en) | 1981-01-20 | 1981-01-20 | Treatment of protein organic solution |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57120599A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8664357B2 (en) | 2008-08-08 | 2014-03-04 | Imperial Innovations Limited | Solvent resistant diafiltration of peptides, PNA or oligonucleotides |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55152507A (en) * | 1979-05-17 | 1980-11-27 | Nitto Electric Ind Co Ltd | Preparation of selective permeable membrane |
| JPS55162311A (en) * | 1979-06-04 | 1980-12-17 | Nitto Electric Ind Co Ltd | Manufacture of selective permeable membrane |
-
1981
- 1981-01-20 JP JP763581A patent/JPS57120599A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55152507A (en) * | 1979-05-17 | 1980-11-27 | Nitto Electric Ind Co Ltd | Preparation of selective permeable membrane |
| JPS55162311A (en) * | 1979-06-04 | 1980-12-17 | Nitto Electric Ind Co Ltd | Manufacture of selective permeable membrane |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8664357B2 (en) | 2008-08-08 | 2014-03-04 | Imperial Innovations Limited | Solvent resistant diafiltration of peptides, PNA or oligonucleotides |
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