JPS57109766A - Novel 1,4-dihydropyridine compound - Google Patents

Novel 1,4-dihydropyridine compound

Info

Publication number
JPS57109766A
JPS57109766A JP56180437A JP18043781A JPS57109766A JP S57109766 A JPS57109766 A JP S57109766A JP 56180437 A JP56180437 A JP 56180437A JP 18043781 A JP18043781 A JP 18043781A JP S57109766 A JPS57109766 A JP S57109766A
Authority
JP
Japan
Prior art keywords
carbon atoms
different
phenyl
alkyl
hydroxyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56180437A
Other languages
English (en)
Inventor
Gorutoman Jiikufuriito
Kunoru Andoreasu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of JPS57109766A publication Critical patent/JPS57109766A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP56180437A 1980-11-13 1981-11-12 Novel 1,4-dihydropyridine compound Pending JPS57109766A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803042769 DE3042769A1 (de) 1980-11-13 1980-11-13 C-3 verknuepfte 1,4-dihydropyridine, ihre verwendung in arzneimitteln und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
JPS57109766A true JPS57109766A (en) 1982-07-08

Family

ID=6116648

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56180437A Pending JPS57109766A (en) 1980-11-13 1981-11-12 Novel 1,4-dihydropyridine compound

Country Status (16)

Country Link
EP (1) EP0052300B1 (ja)
JP (1) JPS57109766A (ja)
AT (1) ATE11773T1 (ja)
AU (1) AU546605B2 (ja)
CA (1) CA1179342A (ja)
DD (1) DD201900A5 (ja)
DE (2) DE3042769A1 (ja)
DK (1) DK501881A (ja)
ES (3) ES8206477A1 (ja)
FI (1) FI813567L (ja)
GR (1) GR76338B (ja)
HU (1) HU186438B (ja)
IL (1) IL64253A (ja)
NO (1) NO813649L (ja)
PT (1) PT73920B (ja)
ZA (1) ZA817840B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63301865A (ja) * 1987-04-15 1988-12-08 ラゴール・エス．ピー．エイ． 合成ポリマー用熱安定剤として有用なポリ１，４−ジヒドロ−２，６−ジメチルリジン−３，５−ジカルボキシルエステル

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3208628A1 (de) * 1982-03-10 1983-09-22 Bayer Ag, 5090 Leverkusen Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
EP0094159B1 (en) * 1982-05-10 1990-03-14 Takeda Chemical Industries, Ltd. Dihydropyridine derivatives, their production and use
US4656181A (en) * 1982-11-24 1987-04-07 Cermol S.A. Esters of 1,4-dihydropyridines, processes for the preparation of the new esters, and medicaments containing the same
EP0145956A1 (de) * 1983-11-16 1985-06-26 Ciba-Geigy Ag Neue Amid-Verbindungen
JPS60120861A (ja) * 1983-12-02 1985-06-28 Otsuka Pharmaceut Co Ltd ジヒドロピリジン誘導体
US4672068A (en) * 1984-05-04 1987-06-09 Fujirebio Kabushiki Kaisha Antihypertensive 1,4-dihydropyridines having a conjugated ester
US4757071A (en) * 1984-12-14 1988-07-12 Nisshin Flour Milling Co., Ltd. 1,4-dihydropyridine derivatives, and pharmaceutical compositions containing same, useful for treating cardiovascular diseases
US5185370A (en) * 1988-09-01 1993-02-09 Orion-Yhtyma Oy Substituted β-diketones and their use
GB9002337D0 (en) * 1990-02-02 1990-04-04 Orion Yhtymae Oy Compounds useful in treating inflammatory bowel disease
IL91382A (en) * 1988-09-01 1995-06-29 Orion Yhtymae Oy Dicitons are converted into alkanyl or ethylmethylene, through their preparation and pharmaceutical preparations containing them
JP2002517440A (ja) * 1998-06-08 2002-06-18 アドバンスド メディスン インコーポレーテッド 新規カルシウムチャンネル薬物および用途
US6897305B2 (en) 1998-06-08 2005-05-24 Theravance, Inc. Calcium channel drugs and uses
US7101909B2 (en) 1998-10-12 2006-09-05 Theravance, Inc. Calcium channel drugs and uses
GB0225548D0 (en) 2002-11-01 2002-12-11 Glaxo Group Ltd Compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795788A1 (de) * 1966-11-16 1975-07-31 Astra Ab Pyridinderivate, verfahren zu deren herstellung und sie enthaltende arzneimittel
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2847236A1 (de) * 1978-10-31 1980-05-14 Bayer Ag Neue dihydropyridine mit substituierten estergruppierungen, mehrer verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63301865A (ja) * 1987-04-15 1988-12-08 ラゴール・エス．ピー．エイ． 合成ポリマー用熱安定剤として有用なポリ１，４−ジヒドロ−２，６−ジメチルリジン−３，５−ジカルボキシルエステル

Also Published As

Publication number Publication date
IL64253A0 (en) 1982-02-28
ES507080A0 (es) 1982-08-16
ES510254A0 (es) 1983-02-01
AU546605B2 (en) 1985-09-12
PT73920B (en) 1983-03-29
CA1179342A (en) 1984-12-11
DE3042769A1 (de) 1982-06-09
ES8303336A1 (es) 1983-02-01
GR76338B (ja) 1984-08-04
FI813567L (fi) 1982-05-14
DE3168955D1 (en) 1985-03-28
PT73920A (en) 1981-12-01
ATE11773T1 (de) 1985-02-15
ES8303337A1 (es) 1983-02-01
ZA817840B (en) 1982-10-27
HU186438B (en) 1985-07-29
DK501881A (da) 1982-05-14
EP0052300A1 (de) 1982-05-26
IL64253A (en) 1985-03-31
EP0052300B1 (de) 1985-02-13
DD201900A5 (de) 1983-08-17
ES510253A0 (es) 1983-02-01
AU7711081A (en) 1982-05-20
ES8206477A1 (es) 1982-08-16
NO813649L (no) 1982-05-14

Similar Documents

Publication Publication Date Title
JPS57109766A (en) Novel 1,4-dihydropyridine compound
IL68075A0 (en) Pyridine and pyrane derivatives,their preparation and pharmaceutical compositions containing them
DE3583872D1 (de) Dihydropyridin-derivate, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische zusammensetzungen, und verfahren zur herstellung dieser zusammensetzungen.
KR950011420A (ko) 트리아진 유도체, 그의 제조 방법 및 용도
NO161678C (no) Analogifremgangsm te for fremstilling av metylendifosfonsyrederivater med antireumatiske egenskaper.
DK0696585T3 (da) Nyt bisoxadiazolidinderivat
ATE45878T1 (de) Pharmazeutische praeparate enthaltend flavenoder thioflaven-derivate, deren verwendung, flavene und thioflavene und verfahren zu deren herstellung.
ATE38675T1 (de) Phosphatesterderivate und ihre verwendung als anti-krebsmittel.
ATE16803T1 (de) Verfahren zur herstellung von 3-(n-arylamino)tetrahydrothiophen-2-on-derivaten.
JPS5732265A (en) Novel 4,4-disubstituted 1,4-dihydropyridine compound
ES8405388A1 (es) Procedimiento para la preparacion de derivados de acidos 5-fenoxibenzoicos de pentitas