ATE38675T1 - Phosphatesterderivate und ihre verwendung als anti-krebsmittel. - Google Patents
Phosphatesterderivate und ihre verwendung als anti-krebsmittel.Info
- Publication number
- ATE38675T1 ATE38675T1 AT86300278T AT86300278T ATE38675T1 AT E38675 T1 ATE38675 T1 AT E38675T1 AT 86300278 T AT86300278 T AT 86300278T AT 86300278 T AT86300278 T AT 86300278T AT E38675 T1 ATE38675 T1 AT E38675T1
- Authority
- AT
- Austria
- Prior art keywords
- sup
- phosphate ester
- cancer agent
- ester derivatives
- sub
- Prior art date
Links
- 229910019142 PO4 Inorganic materials 0.000 title abstract 3
- 239000010452 phosphate Substances 0.000 title abstract 3
- 239000002246 antineoplastic agent Substances 0.000 title abstract 2
- -1 PHOSPHATE ESTER Chemical class 0.000 title 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65525—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a seven-(or more) membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP405485 | 1985-01-16 | ||
| EP86300278A EP0188384B1 (de) | 1985-01-16 | 1986-01-16 | Phosphatesterderivate und ihre Verwendung als Anti-Krebsmittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE38675T1 true ATE38675T1 (de) | 1988-12-15 |
Family
ID=11574166
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86300278T ATE38675T1 (de) | 1985-01-16 | 1986-01-16 | Phosphatesterderivate und ihre verwendung als anti-krebsmittel. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4794183A (de) |
| EP (1) | EP0188384B1 (de) |
| JP (1) | JPS61267592A (de) |
| AT (1) | ATE38675T1 (de) |
| CA (1) | CA1299575C (de) |
| DE (1) | DE3661198D1 (de) |
| ES (1) | ES8704918A1 (de) |
| IE (1) | IE860134L (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4891363A (en) * | 1985-07-26 | 1990-01-02 | Sankyo Company Limited | Cyclic ether derivatives and their use |
| DE3666435D1 (en) * | 1985-08-30 | 1989-11-23 | Sandoz Ag | Substituted hydroxy-heterocyclyl-alkoxy phosphinyloxy trialkylaminium hydroxide inner salt oxides, processes for their preparation and their use as pharmaceuticals |
| JP2556849B2 (ja) * | 1986-02-13 | 1996-11-27 | 三共株式会社 | グリセリン誘導体 |
| KR950002551B1 (en) * | 1986-07-04 | 1995-03-21 | Sankyo Co | Cyclic ether derivatives, their preparation and use |
| US5192766A (en) * | 1989-04-28 | 1993-03-09 | Sankyo Company, Limited | N-acryloylpiperazine derivatives, their preparation and their use as PAF antagonists |
| US5369106A (en) * | 1989-04-28 | 1994-11-29 | Sankyo Company, Limited | N-acryloylpiperazine derivatives, their preparation and their use of PAF antagonists |
| US5248790A (en) * | 1992-06-30 | 1993-09-28 | E. R. Squibb & Sons, Inc. | Aminoalkylphosphonic acid esters of natural 4-methoxy-5-methyl-pyran-3-ol and derivatives thereof |
| US10913767B2 (en) * | 2010-04-22 | 2021-02-09 | Alnylam Pharmaceuticals, Inc. | Oligonucleotides comprising acyclic and abasic nucleosides and analogs |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5772914A (en) * | 1980-10-22 | 1982-05-07 | Takeda Chem Ind Ltd | Antitumor agent |
| ZA866591B (en) * | 1985-08-30 | 1988-04-27 | Sandoz Ltd | Substituted hydroxy-heterocyclyl-alkoxy phosphinyloxy trialkylaminium hydroxide inner salt oxides,processes for their preparation and their use as pharmaceuticals |
-
1986
- 1986-01-07 JP JP61001191A patent/JPS61267592A/ja active Pending
- 1986-01-14 US US06/818,876 patent/US4794183A/en not_active Expired - Fee Related
- 1986-01-16 AT AT86300278T patent/ATE38675T1/de active
- 1986-01-16 IE IE860134A patent/IE860134L/xx unknown
- 1986-01-16 ES ES550971A patent/ES8704918A1/es not_active Expired
- 1986-01-16 DE DE8686300278T patent/DE3661198D1/de not_active Expired
- 1986-01-16 EP EP86300278A patent/EP0188384B1/de not_active Expired
- 1986-01-16 CA CA000499722A patent/CA1299575C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IE860134L (en) | 1986-07-16 |
| US4794183A (en) | 1988-12-27 |
| JPS61267592A (ja) | 1986-11-27 |
| EP0188384A1 (de) | 1986-07-23 |
| CA1299575C (en) | 1992-04-28 |
| ES550971A0 (es) | 1987-04-16 |
| DE3661198D1 (en) | 1988-12-22 |
| ES8704918A1 (es) | 1987-04-16 |
| EP0188384B1 (de) | 1988-11-17 |
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