JPS5664796A - Preparation of 6-aminopenicillanic acid and 6- aminopenicillanic acid s-oxide - Google Patents
Preparation of 6-aminopenicillanic acid and 6- aminopenicillanic acid s-oxideInfo
- Publication number
- JPS5664796A JPS5664796A JP14092879A JP14092879A JPS5664796A JP S5664796 A JPS5664796 A JP S5664796A JP 14092879 A JP14092879 A JP 14092879A JP 14092879 A JP14092879 A JP 14092879A JP S5664796 A JPS5664796 A JP S5664796A
- Authority
- JP
- Japan
- Prior art keywords
- oxide
- aminopenicillanic acid
- arthrobacter
- benzylpenicillin
- prepare
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- NGHVIOIJCVXTGV-ALEPSDHESA-N 6-aminopenicillanic acid Chemical compound [O-]C(=O)[C@H]1C(C)(C)S[C@@H]2[C@H]([NH3+])C(=O)N21 NGHVIOIJCVXTGV-ALEPSDHESA-N 0.000 title abstract 4
- NGHVIOIJCVXTGV-UHFFFAOYSA-N 6beta-amino-penicillanic acid Natural products OC(=O)C1C(C)(C)SC2C(N)C(=O)N21 NGHVIOIJCVXTGV-UHFFFAOYSA-N 0.000 title abstract 4
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 6
- 241000186063 Arthrobacter Species 0.000 abstract 4
- 102000004190 Enzymes Human genes 0.000 abstract 3
- 108090000790 Enzymes Proteins 0.000 abstract 3
- RCCPEORTSYDPMB-UHFFFAOYSA-N hydroxy benzenecarboximidothioate Chemical compound OSC(=N)C1=CC=CC=C1 RCCPEORTSYDPMB-UHFFFAOYSA-N 0.000 abstract 3
- 235000019371 penicillin G benzathine Nutrition 0.000 abstract 3
- 229940056360 penicillin g Drugs 0.000 abstract 3
- 241000894006 Bacteria Species 0.000 abstract 2
- 239000001963 growth medium Substances 0.000 abstract 2
- 238000005273 aeration Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000012136 culture method Methods 0.000 abstract 1
- 238000006911 enzymatic reaction Methods 0.000 abstract 1
- 210000003495 flagella Anatomy 0.000 abstract 1
- 238000009630 liquid culture Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
- C12P37/06—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin by desacylation of the substituent in the 6 position
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/06—Arthrobacter
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/83—Arthrobacter
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14092879A JPS5664796A (en) | 1979-10-30 | 1979-10-30 | Preparation of 6-aminopenicillanic acid and 6- aminopenicillanic acid s-oxide |
| US06/194,277 US4370414A (en) | 1979-10-30 | 1980-10-06 | Process for producing 6-aminopenicillanic acid and 6-aminopenicillanic acid S-oxide |
| CA000362952A CA1159783A (en) | 1979-10-30 | 1980-10-22 | Process for producing 6-aminopenicillanic acid and 6-aminopenicillanic acid s-oxide |
| FR8022680A FR2468610A1 (fr) | 1979-10-30 | 1980-10-23 | Procede de production enzymatique d'acide 6-aminopenicillanique et de s-oxyde d'acide 6-aminopenicillanique et nouveaux produits ainsi obtenus |
| DE19803040951 DE3040951A1 (de) | 1979-10-30 | 1980-10-30 | Verfahren zur herstellung von 6-amino-penicillansaeure oder deren s-oxid |
| GB8034898A GB2061943B (en) | 1979-10-30 | 1980-10-30 | Process for producing 6-aminopenicillanic acid or 6-aminopenicillanic acid s-oxide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14092879A JPS5664796A (en) | 1979-10-30 | 1979-10-30 | Preparation of 6-aminopenicillanic acid and 6- aminopenicillanic acid s-oxide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5664796A true JPS5664796A (en) | 1981-06-02 |
Family
ID=15280066
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP14092879A Pending JPS5664796A (en) | 1979-10-30 | 1979-10-30 | Preparation of 6-aminopenicillanic acid and 6- aminopenicillanic acid s-oxide |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4370414A (OSRAM) |
| JP (1) | JPS5664796A (OSRAM) |
| CA (1) | CA1159783A (OSRAM) |
| DE (1) | DE3040951A1 (OSRAM) |
| FR (1) | FR2468610A1 (OSRAM) |
| GB (1) | GB2061943B (OSRAM) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5252470A (en) * | 1988-03-24 | 1993-10-12 | Kyowa Hakko Kogyo Co., Ltd. | D-amidase and process for producing D-α-alanine and/or L-α-alanineamide |
| CA1336414C (en) * | 1988-03-24 | 1995-07-25 | Hideki Kawasaki | D-amidase and process for producing d--alanine and/or l--alanineamide |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS502758A (OSRAM) * | 1973-05-11 | 1975-01-13 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3116218A (en) * | 1962-07-17 | 1963-12-31 | Bayer Ag | Process for the production of penicillin-splitting enzyme preparations |
| GB1009028A (en) * | 1963-04-22 | 1965-11-03 | Beecham Res Lab | Enzymatic production of 6-aminopenicillanic acid |
| US3239428A (en) * | 1964-04-30 | 1966-03-08 | Banyu Pharma Co Ltd | Preparation of 6-aminopenicillanic acid by arthrobacter viscosus |
| US3446705A (en) * | 1967-03-30 | 1969-05-27 | Squibb & Sons Inc | Method for the production of 6-amino-penicillanic acid |
| JPS5535120B2 (OSRAM) * | 1973-09-21 | 1980-09-11 |
-
1979
- 1979-10-30 JP JP14092879A patent/JPS5664796A/ja active Pending
-
1980
- 1980-10-06 US US06/194,277 patent/US4370414A/en not_active Expired - Lifetime
- 1980-10-22 CA CA000362952A patent/CA1159783A/en not_active Expired
- 1980-10-23 FR FR8022680A patent/FR2468610A1/fr active Granted
- 1980-10-30 DE DE19803040951 patent/DE3040951A1/de not_active Withdrawn
- 1980-10-30 GB GB8034898A patent/GB2061943B/en not_active Expired
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS502758A (OSRAM) * | 1973-05-11 | 1975-01-13 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA1159783A (en) | 1984-01-03 |
| GB2061943A (en) | 1981-05-20 |
| DE3040951A1 (de) | 1981-05-14 |
| US4370414A (en) | 1983-01-25 |
| FR2468610A1 (fr) | 1981-05-08 |
| FR2468610B1 (OSRAM) | 1983-07-18 |
| GB2061943B (en) | 1984-09-26 |
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