GB1009028A - Enzymatic production of 6-aminopenicillanic acid - Google Patents

Enzymatic production of 6-aminopenicillanic acid

Info

Publication number
GB1009028A
GB1009028A GB1569263A GB1569263A GB1009028A GB 1009028 A GB1009028 A GB 1009028A GB 1569263 A GB1569263 A GB 1569263A GB 1569263 A GB1569263 A GB 1569263A GB 1009028 A GB1009028 A GB 1009028A
Authority
GB
United Kingdom
Prior art keywords
aminopenicillanic acid
enzymatic production
nclb
achromobacter
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1569263A
Inventor
Frank Ralph Batchelor
Martin Cole
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Research Laboratories Ltd
Original Assignee
Beecham Research Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Research Laboratories Ltd filed Critical Beecham Research Laboratories Ltd
Priority to GB1569263A priority Critical patent/GB1009028A/en
Publication of GB1009028A publication Critical patent/GB1009028A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/42—Compounds with a free primary amino radical attached in position 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

6-Aminopenicillanic acid is prepared by treating phenoxymethylpenicillin or a salt thereof, or a fermentation liquor containing the aforesaid penicillin or a salt thereof, at a pH of at least 7 with a penicillin amidase enzyme preparation derived from Achromobacter sp. Achromobacter sp. NClB 9424, A. arsenoxydans NClB 8687 and A. anitratus NCTC 8102 are specified micro-organisms. Cultivation and isolation is according to the parent Specification.
GB1569263A 1963-04-22 1963-04-22 Enzymatic production of 6-aminopenicillanic acid Expired GB1009028A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1569263A GB1009028A (en) 1963-04-22 1963-04-22 Enzymatic production of 6-aminopenicillanic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1569263A GB1009028A (en) 1963-04-22 1963-04-22 Enzymatic production of 6-aminopenicillanic acid

Publications (1)

Publication Number Publication Date
GB1009028A true GB1009028A (en) 1965-11-03

Family

ID=10063734

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1569263A Expired GB1009028A (en) 1963-04-22 1963-04-22 Enzymatic production of 6-aminopenicillanic acid

Country Status (1)

Country Link
GB (1) GB1009028A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2468610A1 (en) * 1979-10-30 1981-05-08 Shionogi & Co PROCESS FOR ENZYMATIC PRODUCTION OF 6-AMINOPENICILLANIC ACID AND 6-AMINOPENICILLANIC ACID S-OXIDE AND NOVEL PRODUCTS THUS OBTAINED

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2468610A1 (en) * 1979-10-30 1981-05-08 Shionogi & Co PROCESS FOR ENZYMATIC PRODUCTION OF 6-AMINOPENICILLANIC ACID AND 6-AMINOPENICILLANIC ACID S-OXIDE AND NOVEL PRODUCTS THUS OBTAINED

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