JPS5642589A - Highly thermophile fumarase, its production and production of l-malic acid utilizing microorganism producing thermophile fumarase and the same - Google Patents

Highly thermophile fumarase, its production and production of l-malic acid utilizing microorganism producing thermophile fumarase and the same

Info

Publication number
JPS5642589A
JPS5642589A JP11883579A JP11883579A JPS5642589A JP S5642589 A JPS5642589 A JP S5642589A JP 11883579 A JP11883579 A JP 11883579A JP 11883579 A JP11883579 A JP 11883579A JP S5642589 A JPS5642589 A JP S5642589A
Authority
JP
Japan
Prior art keywords
fumarase
thermophile
production
highly
malic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11883579A
Other languages
Japanese (ja)
Other versions
JPS637756B2 (en
Inventor
Kazuo Kimura
Kenichiro Takayama
Atsushi Yasudo
Tamotsu Kawamoto
Mikio Kawamori
Izumi Masunaga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP11883579A priority Critical patent/JPS5642589A/en
Publication of JPS5642589A publication Critical patent/JPS5642589A/en
Publication of JPS637756B2 publication Critical patent/JPS637756B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts

Landscapes

  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

PURPOSE: Highly thermophile fumarase is produced by the cultivation of a microorganism belonging to Thermus or Bacillus and the resultant enzyme is made to act on fumaric acid, thus producing L-malic acid.
CONSTITUTION: A microorganism that belongs to Thermus or Bacillus and can produce highly thermophile fumarase, e.g., Thermus aquatics No.104 (FERM- 5150) or Bacillus licheniformis T-511 (FERM-5151), is inoculated in an enriched medium and subjected to liquid culture to produce a highly thermophile fumarase which works optimally at 50W80°C in the medium. The enzyme is collected or the cells of the microorganism or its treated product are collected and they are made to act on fumaric acid at 40W80°C to form L-malic acid in the reaction mixture and the L-malic acid is collected.
COPYRIGHT: (C)1981,JPO&Japio
JP11883579A 1979-09-18 1979-09-18 Highly thermophile fumarase, its production and production of l-malic acid utilizing microorganism producing thermophile fumarase and the same Granted JPS5642589A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11883579A JPS5642589A (en) 1979-09-18 1979-09-18 Highly thermophile fumarase, its production and production of l-malic acid utilizing microorganism producing thermophile fumarase and the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11883579A JPS5642589A (en) 1979-09-18 1979-09-18 Highly thermophile fumarase, its production and production of l-malic acid utilizing microorganism producing thermophile fumarase and the same

Related Child Applications (3)

Application Number Title Priority Date Filing Date
JP62090452A Division JPS6322181A (en) 1987-04-13 1987-04-13 Novel bacterial strain thermus rubens
JP9045387A Division JPS6322193A (en) 1987-04-13 1987-04-13 Production of l-malic acid
JP62090451A Division JPS6322180A (en) 1987-04-13 1987-04-13 Novel bacterial strain thermus lacteus

Publications (2)

Publication Number Publication Date
JPS5642589A true JPS5642589A (en) 1981-04-20
JPS637756B2 JPS637756B2 (en) 1988-02-18

Family

ID=14746326

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11883579A Granted JPS5642589A (en) 1979-09-18 1979-09-18 Highly thermophile fumarase, its production and production of l-malic acid utilizing microorganism producing thermophile fumarase and the same

Country Status (1)

Country Link
JP (1) JPS5642589A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4551432A (en) * 1983-11-14 1985-11-05 Uop Inc. Paracoccus denitrificans, FUM-14: a fumarase overproducer
WO1992012251A1 (en) * 1991-01-14 1992-07-23 Bior Inc. Process for producing (r)-malic acid, microbial maleate hydratase, and process for producing said hydratase

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4551432A (en) * 1983-11-14 1985-11-05 Uop Inc. Paracoccus denitrificans, FUM-14: a fumarase overproducer
WO1992012251A1 (en) * 1991-01-14 1992-07-23 Bior Inc. Process for producing (r)-malic acid, microbial maleate hydratase, and process for producing said hydratase
US5270190A (en) * 1991-01-14 1993-12-14 Bior Inc. Method for producing (R)-malic acid from maleic acid using microbial maleate hydratase

Also Published As

Publication number Publication date
JPS637756B2 (en) 1988-02-18

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