JPS5632497A - N6-omega-aminoalkyladenosine-3'-monophosphate - Google Patents
N6-omega-aminoalkyladenosine-3'-monophosphateInfo
- Publication number
- JPS5632497A JPS5632497A JP10838179A JP10838179A JPS5632497A JP S5632497 A JPS5632497 A JP S5632497A JP 10838179 A JP10838179 A JP 10838179A JP 10838179 A JP10838179 A JP 10838179A JP S5632497 A JPS5632497 A JP S5632497A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- monophosphate
- salt
- aminoalkyladenosine
- cyclic monophosphate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:The titled monophosphate (hereinafter referred to as N6-ω-aminoalkyl-3'-AMP) expressed by formula I (n is an integer 1W20), or a salt thereof.
EXAMPLE: N6-(2-aminoethyl)-3'-AMP.
USE: An antiallergic agent.
PROCESS: After protecting the hydroxyl group at the 2'-position with an acyl group, inosine-3',5'-cyclic monophosphate is reacted with phosphorus oxychloride in a solvent, e.g. diethylaniline, to give a 6-halogenopurine-9-β-D-ribofuranosyl-3',5'- cyclic monophosphate (salt) expressed by formula II (X is halogen), which is then reacted with a 1,ω-diaminoalkane of the formula H2N(CH2)nNH2 (n is an integer 1W20) to give the compound of formula I together with an N6-ω-aminoalkyladenosine-3',5'-cyclic monophosphate (salt).
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10838179A JPS5632497A (en) | 1979-08-24 | 1979-08-24 | N6-omega-aminoalkyladenosine-3'-monophosphate |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10838179A JPS5632497A (en) | 1979-08-24 | 1979-08-24 | N6-omega-aminoalkyladenosine-3'-monophosphate |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5632497A true JPS5632497A (en) | 1981-04-01 |
Family
ID=14483321
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10838179A Pending JPS5632497A (en) | 1979-08-24 | 1979-08-24 | N6-omega-aminoalkyladenosine-3'-monophosphate |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5632497A (en) |
-
1979
- 1979-08-24 JP JP10838179A patent/JPS5632497A/en active Pending
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