JPS56142296A - Adenosine derivative and its preparation - Google Patents

Adenosine derivative and its preparation

Info

Publication number
JPS56142296A
JPS56142296A JP4606180A JP4606180A JPS56142296A JP S56142296 A JPS56142296 A JP S56142296A JP 4606180 A JP4606180 A JP 4606180A JP 4606180 A JP4606180 A JP 4606180A JP S56142296 A JPS56142296 A JP S56142296A
Authority
JP
Japan
Prior art keywords
formula
adenosine
group
adenosine derivative
acyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4606180A
Other languages
Japanese (ja)
Inventor
Morio Ikehara
Eiko Otsuka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
WAKINAGA YAKUHIN KK
Wakunaga Pharmaceutical Co Ltd
Original Assignee
WAKINAGA YAKUHIN KK
Wakunaga Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by WAKINAGA YAKUHIN KK, Wakunaga Pharmaceutical Co Ltd filed Critical WAKINAGA YAKUHIN KK
Priority to JP4606180A priority Critical patent/JPS56142296A/en
Publication of JPS56142296A publication Critical patent/JPS56142296A/en
Pending legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

NEW MATERIAL:An adenosine derivative of formula I (group of formula II is the skeleton of adenine riboside; Z is H or group of formula III; Ac is acyl; Ph and Ph' are phenyl or substituted phenyl; NB is o-nitro-4- and/or 5-unsubstituted or substituted benzyl).
EXAMPLE: 5'-O-Dianilinophosphoryl-N6-benzoyl-3'-O-(o-nitrobenzyl)-adenosine.
USE: A synthetic intermediate for 5'-triphosphoryladenylyl-(2'-5')-adenylyl-(2'-5')- adenosine of formula IV, having an inhibitory action on the proteinic synthesis, found in cells treated with interferon, and expected as a carcinostatic agent.
PROCESS: An adenosine derivative of formula V (Ac and Ac' are acyl) is condensed with a dianilinophosphoric acid halide of formula VI (X is halogen), and the protecting group of the 2'-hydroxyl group is removed.
COPYRIGHT: (C)1981,JPO&Japio
JP4606180A 1980-04-08 1980-04-08 Adenosine derivative and its preparation Pending JPS56142296A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4606180A JPS56142296A (en) 1980-04-08 1980-04-08 Adenosine derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4606180A JPS56142296A (en) 1980-04-08 1980-04-08 Adenosine derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS56142296A true JPS56142296A (en) 1981-11-06

Family

ID=12736489

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4606180A Pending JPS56142296A (en) 1980-04-08 1980-04-08 Adenosine derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS56142296A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4981957A (en) * 1984-07-19 1991-01-01 Centre National De La Recherche Scientifique Oligonucleotides with modified phosphate and modified carbohydrate moieties at the respective chain termini
JP2008267181A (en) * 2007-04-17 2008-11-06 Fujitsu General Ltd Cross flow fan

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4981957A (en) * 1984-07-19 1991-01-01 Centre National De La Recherche Scientifique Oligonucleotides with modified phosphate and modified carbohydrate moieties at the respective chain termini
JP2008267181A (en) * 2007-04-17 2008-11-06 Fujitsu General Ltd Cross flow fan

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