JPS5626887A - Preparation of 5-benzyl-3-furancarboxylic acid ester - Google Patents
Preparation of 5-benzyl-3-furancarboxylic acid esterInfo
- Publication number
- JPS5626887A JPS5626887A JP10339879A JP10339879A JPS5626887A JP S5626887 A JPS5626887 A JP S5626887A JP 10339879 A JP10339879 A JP 10339879A JP 10339879 A JP10339879 A JP 10339879A JP S5626887 A JPS5626887 A JP S5626887A
- Authority
- JP
- Japan
- Prior art keywords
- acid ester
- furancarboxylic acid
- formula
- benzyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Furan Compounds (AREA)
Abstract
PURPOSE: To prepare the titled compound useful as an intermediate of pharmaceuticals and pesticides, economically, in a short step, by reacting 5-methyl-3-furancarboxylic acid ester with a specific amount of bromine, and then subjecting the reaction product to Friedel-Crafts reaction with benzene.
CONSTITUTION: A 5-methyl-3-furancarboxylic acid ester of formula II (R is ester residue) is made to react with equimolar amount of or slightly excessive (1.0W1.1 times mole of) bromine at room temperature (especially ≤10°C) to obtain a 5- bromomethyl-3-furancarboxylic acid ester of formula III selectively. The compound of formula III is reacted with benzene in the presence of a Friedel-Crafts catalyst to afford a 5-benzyl-3-furancarboxylic acid ester of formula I in a short reaction step, economically. The compound of formula I is useful for the synthesis of the alcohol moiety of a synthetic pyrethroid compound useful especially as an insecticide.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10339879A JPS5626887A (en) | 1979-08-14 | 1979-08-14 | Preparation of 5-benzyl-3-furancarboxylic acid ester |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10339879A JPS5626887A (en) | 1979-08-14 | 1979-08-14 | Preparation of 5-benzyl-3-furancarboxylic acid ester |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5626887A true JPS5626887A (en) | 1981-03-16 |
JPS6228791B2 JPS6228791B2 (en) | 1987-06-23 |
Family
ID=14352945
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10339879A Granted JPS5626887A (en) | 1979-08-14 | 1979-08-14 | Preparation of 5-benzyl-3-furancarboxylic acid ester |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5626887A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5933050U (en) * | 1982-08-23 | 1984-02-29 | キヤノン株式会社 | heating device |
-
1979
- 1979-08-14 JP JP10339879A patent/JPS5626887A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5933050U (en) * | 1982-08-23 | 1984-02-29 | キヤノン株式会社 | heating device |
Also Published As
Publication number | Publication date |
---|---|
JPS6228791B2 (en) | 1987-06-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
LAPS | Cancellation because of no payment of annual fees |