JPS5583780A - Novel 4-(3-methyl-2-thienyl)benzene derivative - Google Patents
Novel 4-(3-methyl-2-thienyl)benzene derivativeInfo
- Publication number
- JPS5583780A JPS5583780A JP15572878A JP15572878A JPS5583780A JP S5583780 A JPS5583780 A JP S5583780A JP 15572878 A JP15572878 A JP 15572878A JP 15572878 A JP15572878 A JP 15572878A JP S5583780 A JPS5583780 A JP S5583780A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- thienyl
- methyl
- compound
- benzene derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:A 4-(3-methyl-2-thienyl)-benzene derivative of formula I: (R is halogen, alkyl, CN, NH2, NO2, acetyl group which may be protected optionally, -MgX, etc.). EXAMPLE:4-(3-Methyl-2-thienyl)-acetophenone. USE:Intermediates for the synthesis of antiphlogistics and analgesics, capable of synthesizing the compound of formula II having improved actions, usable continuously with low toxicity and side effects. PROCESS:A compound of formula III: (X is halogen) is reacted with a compound of formula IV in a solvent, e.g. THF, in the presence of a catalyst, e.g. palladium chloride, at a reflux temperature of the solvent to give the compound of formula I.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15572878A JPS5583780A (en) | 1978-12-19 | 1978-12-19 | Novel 4-(3-methyl-2-thienyl)benzene derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15572878A JPS5583780A (en) | 1978-12-19 | 1978-12-19 | Novel 4-(3-methyl-2-thienyl)benzene derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5583780A true JPS5583780A (en) | 1980-06-24 |
JPS6225146B2 JPS6225146B2 (en) | 1987-06-01 |
Family
ID=15612158
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15572878A Granted JPS5583780A (en) | 1978-12-19 | 1978-12-19 | Novel 4-(3-methyl-2-thienyl)benzene derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5583780A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011219398A (en) * | 2010-04-07 | 2011-11-04 | Mitsui Chemicals Agro Inc | Method for producing branched aliphatic aldehyde |
-
1978
- 1978-12-19 JP JP15572878A patent/JPS5583780A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011219398A (en) * | 2010-04-07 | 2011-11-04 | Mitsui Chemicals Agro Inc | Method for producing branched aliphatic aldehyde |
Also Published As
Publication number | Publication date |
---|---|
JPS6225146B2 (en) | 1987-06-01 |
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