JPS5473774A - Isoxazoline-3-one derivative - Google Patents
Isoxazoline-3-one derivativeInfo
- Publication number
- JPS5473774A JPS5473774A JP13961277A JP13961277A JPS5473774A JP S5473774 A JPS5473774 A JP S5473774A JP 13961277 A JP13961277 A JP 13961277A JP 13961277 A JP13961277 A JP 13961277A JP S5473774 A JPS5473774 A JP S5473774A
- Authority
- JP
- Japan
- Prior art keywords
- isoxazoline
- formula
- derivative
- phenyl
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:An isoxazoline-3-one derivative of formula I: (R1 is H or lower alkyl group; R2 is aryl, heterocyclic group; R3 is lower alkyl, lower alkenyl, aralkenyl, lower alkynyl, or aralkynyl group).
EXAMPLE: 2-(3-Phenyl-2-propynyl)-5-phenyl-4-isoxazoline-3-one.
USE: Pharmaceuticals having anti-inflammatory, analgesic, and antipyretic actions.
PROCESS: A 3-hydroxyisoxazole is reacted with 1.0W2.0 moles of a halogen compound of formula III: (X is halogen, e.g. Cl, Br, I, etc.) in an inert solvent, e.g. benzene, methanol, etc., if necessary, in the presence of a base, e.g. potassium, sodium hydroxides, etc. at 0W150°C, preferably 20W130°C to give the compound of formula I.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13961277A JPS5473774A (en) | 1977-11-21 | 1977-11-21 | Isoxazoline-3-one derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13961277A JPS5473774A (en) | 1977-11-21 | 1977-11-21 | Isoxazoline-3-one derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5473774A true JPS5473774A (en) | 1979-06-13 |
Family
ID=15249334
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP13961277A Pending JPS5473774A (en) | 1977-11-21 | 1977-11-21 | Isoxazoline-3-one derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5473774A (en) |
-
1977
- 1977-11-21 JP JP13961277A patent/JPS5473774A/en active Pending
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS56110665A (en) | Sulfamoyl-substituted phenetylamine derivative and its preparation | |
JPS54117486A (en) | 2-phenoxypyrimidine derivative | |
JPS5473775A (en) | Isoxazoline-3-one derivative | |
JPS5473774A (en) | Isoxazoline-3-one derivative | |
JPS5583791A (en) | 7-methoxycephalosporin derivative and its preparation | |
JPS5473772A (en) | Isoxazoline-3-one derivative | |
JPS55145648A (en) | New derivative of anthranylic acid | |
JPS537640A (en) | Synthesis of diphenylamine derivatives | |
JPS5515460A (en) | Novel 2-substituted-benzoylpropionic acid derivative | |
JPS51149277A (en) | Process for preparing new benzotriazole compounds | |
JPS55104274A (en) | Isoxazolin-3-one derivative and its preparation | |
JPS5695161A (en) | 2-admantanon derivative | |
GB2011897A (en) | Process for Preparing Anthranylaldehyde Derivatives | |
JPS5231067A (en) | Synthesis of 2-(2-formyl-1-pyrrolyl)- benzophenone derivatives | |
JPS5646889A (en) | Gold compound and its preparation | |
JPS5643271A (en) | Production of 4-benzoyl-5-hydroxypyrazole | |
JPS54115357A (en) | 5,6-dithiocalicene derivative and its preparation | |
JPS54151946A (en) | Alpha-sulfonyl-alpha-aromatic group substituted propionic acid derivative | |
JPS54100371A (en) | Novel imidazole c-nucleoside derivative | |
JPS5490158A (en) | Novel benzoylphenoxyacetic acid derivatives | |
JPS5690033A (en) | 1,3-disubstituted cyclohexene derivative | |
JPS5527141A (en) | Novel 2-pyridyl-imidazole-carboxamide derivative | |
ES8503005A1 (en) | Penicillin derivatives. | |
JPS5212928A (en) | Herbicides | |
JPS5639090A (en) | 5-substituted uracil derivative and its preparation |