JPS5569535A - Preparation of dihydro-coenzyme q analog compound - Google Patents

Preparation of dihydro-coenzyme q analog compound

Info

Publication number
JPS5569535A
JPS5569535A JP14208278A JP14208278A JPS5569535A JP S5569535 A JPS5569535 A JP S5569535A JP 14208278 A JP14208278 A JP 14208278A JP 14208278 A JP14208278 A JP 14208278A JP S5569535 A JPS5569535 A JP S5569535A
Authority
JP
Japan
Prior art keywords
compound
reaction
coenzyme
pulenol
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14208278A
Other languages
Japanese (ja)
Other versions
JPS5929173B2 (en
Inventor
Hirokazu Ryono
Arahiko Eguchi
Fusayoshi Kakizaki
Hirosumi Etou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP14208278A priority Critical patent/JPS5929173B2/en
Publication of JPS5569535A publication Critical patent/JPS5569535A/en
Publication of JPS5929173B2 publication Critical patent/JPS5929173B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To prepare the title compound useful as a raw material of coenzyme Q, easily, safely, and in high yield, by reacting a hydroquinone derivative with pulenol in the presence of an acidic condensation catalyst in a nitro compound as a reaction solvent.
CONSTITUTION: The objective compound V (R1 is IV; A, B are H or A-B is a bond; R2 is H or acyl; R3 is H or alkyl), e.g. co-enzyme Q10, is prepared by reacting a hydroquinone derivative of formula I (e.g. 2,3-dimethoxy-5-methylbenzohydroquinone) with pulenol or its reactive derivative of formula II or III (e.g. isodecapulenol or its ester, halide, etc.), in a nitro compound such as nitromethane, nitrobenzene, etc., in the presence of an acidic condensation catalyst.
EFFECT: High reaction yield, high production ratio of Δ2-trans compound in the main products, high rate of reaction, reduced amount of the catalyst, and suppressed corrosion of the reaction apparatus.
COPYRIGHT: (C)1980,JPO&Japio
JP14208278A 1978-11-17 1978-11-17 Method for producing dihydrocoenzyme Q compound Expired JPS5929173B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP14208278A JPS5929173B2 (en) 1978-11-17 1978-11-17 Method for producing dihydrocoenzyme Q compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14208278A JPS5929173B2 (en) 1978-11-17 1978-11-17 Method for producing dihydrocoenzyme Q compound

Publications (2)

Publication Number Publication Date
JPS5569535A true JPS5569535A (en) 1980-05-26
JPS5929173B2 JPS5929173B2 (en) 1984-07-18

Family

ID=15307008

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14208278A Expired JPS5929173B2 (en) 1978-11-17 1978-11-17 Method for producing dihydrocoenzyme Q compound

Country Status (1)

Country Link
JP (1) JPS5929173B2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009505969A (en) * 2005-08-10 2009-02-12 ディーエスエム アイピー アセッツ ビー．ブイ． Preparation method of ubihydroquinone and ubiquinone

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009505969A (en) * 2005-08-10 2009-02-12 ディーエスエム アイピー アセッツ ビー．ブイ． Preparation method of ubihydroquinone and ubiquinone
KR101366958B1 (en) * 2005-08-10 2014-03-12 디에스엠 아이피 어셋츠 비.브이. Process for the preparation of ubihydroquinones and ubiquinones

Also Published As

Publication number Publication date
JPS5929173B2 (en) 1984-07-18

Similar Documents

Publication Publication Date Title
JPS5569535A (en) Preparation of dihydro-coenzyme q analog compound
JPS5695142A (en) Preparation of aliphatic aldehyde
JPS5655355A (en) Preparation of alkylenediamine derivative
JPS5679628A (en) Preparation of isoprene
JPS5655345A (en) Preparation of 2-pentenoate ester
JPS55111468A (en) Preparation of n-benzyl-tetrahydro isoquinoline derivative
JPS5562040A (en) Preparation of alpha-ketocarboxylic acids or their esters
JPS56108743A (en) 3-nitro-2-hydroxy-4-phenylbutyric acid derivative, its ester and preparation thereof
JPS5699480A (en) Preparation of pyridopyrimidine derivative
JPS5527161A (en) Production of alcohol or its ether derivative
JPS5618936A (en) Production of phenylacetic acid
JPS5538347A (en) Preparation of indazoleacetic acids
JPS56123927A (en) Preparation of hydroquinone and quinone derivative
JPS57149283A (en) Long-chain fatty acid lactol
JPS55108898A (en) 25-hydroxy-24-oxocholesterol derivative and its preparation
JPS5257142A (en) Process for preparing dihalovinyl-cyclopropanecarboxylic acid derivati ves
JPS55151548A (en) Production of guanidinocaproic ester
JPS5522613A (en) Preparation of 2-hydroxy-3-butenoic acid derivative
JPS5498754A (en) 3-hydroxy-3-bromomethylphthalide derivative
JPS5692238A (en) Separation and recovery of hydroquinone derivative
JPS5564538A (en) Preparation of dihydrocoenzyme q compound
JPS5262234A (en) Process for preparation of n_3'-hydroxyphenyl-2-methylbenzamide
JPS5772963A (en) Alpha-(2-pyridyl)arylacetaldehyde
JPS56161388A (en) Novel vincamine derivative
JPS57149270A (en) Preparation of 3,4,5,6,7,8-hexahydrocarbostyril-5-one