JPS5547690A - Cephem compound, its salt, their preparation, and preventives and remedies for microbism comprising them as active constituents - Google Patents
Cephem compound, its salt, their preparation, and preventives and remedies for microbism comprising them as active constituentsInfo
- Publication number
- JPS5547690A JPS5547690A JP11661679A JP11661679A JPS5547690A JP S5547690 A JPS5547690 A JP S5547690A JP 11661679 A JP11661679 A JP 11661679A JP 11661679 A JP11661679 A JP 11661679A JP S5547690 A JPS5547690 A JP S5547690A
- Authority
- JP
- Japan
- Prior art keywords
- salt
- compound
- amino
- formula
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- -1 Cephem compound Chemical class 0.000 title abstract 4
- 150000003839 salts Chemical class 0.000 title abstract 4
- 239000000470 constituent Substances 0.000 title 1
- 230000003449 preventive effect Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 241000192125 Firmicutes Species 0.000 abstract 1
- 230000009435 amidation Effects 0.000 abstract 1
- 238000007112 amidation reaction Methods 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 244000000010 microbial pathogen Species 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 150000003952 β-lactams Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7836399 | 1978-09-11 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62082089A Division JPS62289584A (ja) | 1978-09-11 | 1987-04-01 | セフエム化合物およびその塩類 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5547690A true JPS5547690A (en) | 1980-04-04 |
JPH0144716B2 JPH0144716B2 (enrdf_load_stackoverflow) | 1989-09-29 |
Family
ID=10499589
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP11661679A Granted JPS5547690A (en) | 1978-09-11 | 1979-09-10 | Cephem compound, its salt, their preparation, and preventives and remedies for microbism comprising them as active constituents |
JP62082089A Pending JPS62289584A (ja) | 1978-09-11 | 1987-04-01 | セフエム化合物およびその塩類 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62082089A Pending JPS62289584A (ja) | 1978-09-11 | 1987-04-01 | セフエム化合物およびその塩類 |
Country Status (2)
Country | Link |
---|---|
JP (2) | JPS5547690A (enrdf_load_stackoverflow) |
BE (1) | BE878637A (enrdf_load_stackoverflow) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4252802A (en) * | 1980-03-13 | 1981-02-24 | E. R. Squibb & Sons, Inc. | Hydroxamic acid derivatives of 7-[(2-amino-4-thiazolyl)-oximino] cephalosporins |
JPS6011917B2 (ja) * | 1981-04-09 | 1985-03-28 | 山之内製薬株式会社 | 新規なセファロスポリン化合物 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS51149296A (en) * | 1975-06-09 | 1976-12-22 | Takeda Chem Ind Ltd | Cephems or penams and their preparation |
JPS52125190A (en) * | 1976-04-12 | 1977-10-20 | Fujisawa Pharmaceut Co Ltd | 3,7-disubstituted-3-cephem-4-carboxylic acids, their salts and their preparation |
JPS5334795A (en) * | 1976-09-08 | 1978-03-31 | Takeda Chem Ind Ltd | Cephalosporin derivatives and their preparation |
JPS549296A (en) * | 1977-04-02 | 1979-01-24 | Hoechst Ag | Cephem derivative and its preparation |
JPS54132593A (en) * | 1978-03-31 | 1979-10-15 | Roussel Uclaf | Novel oosubstituted oxime derivatives of 77aminothiazolylacetoamidecephalosporanic acid*their manufacture*their use as drug and composition containing them |
JPS5858353A (ja) * | 1981-09-30 | 1983-04-06 | ピ−シ−株式会社 | 強化コンクリ−ト構造体 |
-
1979
- 1979-09-06 BE BE0/197041A patent/BE878637A/fr not_active IP Right Cessation
- 1979-09-10 JP JP11661679A patent/JPS5547690A/ja active Granted
-
1987
- 1987-04-01 JP JP62082089A patent/JPS62289584A/ja active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS51149296A (en) * | 1975-06-09 | 1976-12-22 | Takeda Chem Ind Ltd | Cephems or penams and their preparation |
JPS52125190A (en) * | 1976-04-12 | 1977-10-20 | Fujisawa Pharmaceut Co Ltd | 3,7-disubstituted-3-cephem-4-carboxylic acids, their salts and their preparation |
JPS5334795A (en) * | 1976-09-08 | 1978-03-31 | Takeda Chem Ind Ltd | Cephalosporin derivatives and their preparation |
JPS549296A (en) * | 1977-04-02 | 1979-01-24 | Hoechst Ag | Cephem derivative and its preparation |
JPS54132593A (en) * | 1978-03-31 | 1979-10-15 | Roussel Uclaf | Novel oosubstituted oxime derivatives of 77aminothiazolylacetoamidecephalosporanic acid*their manufacture*their use as drug and composition containing them |
JPS5858353A (ja) * | 1981-09-30 | 1983-04-06 | ピ−シ−株式会社 | 強化コンクリ−ト構造体 |
Also Published As
Publication number | Publication date |
---|---|
BE878637A (fr) | 1980-03-06 |
JPS62289584A (ja) | 1987-12-16 |
JPH0144716B2 (enrdf_load_stackoverflow) | 1989-09-29 |
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