JPS552602A - 1-beta-d-arabinofranosylcytosine-5'-phosphoric acid oleyl ester - Google Patents

1-beta-d-arabinofranosylcytosine-5'-phosphoric acid oleyl ester

Info

Publication number
JPS552602A
JPS552602A JP7369978A JP7369978A JPS552602A JP S552602 A JPS552602 A JP S552602A JP 7369978 A JP7369978 A JP 7369978A JP 7369978 A JP7369978 A JP 7369978A JP S552602 A JPS552602 A JP S552602A
Authority
JP
Japan
Prior art keywords
arabinofranosylcytosine
phosphoric acid
beta
oleyl ester
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7369978A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5726680B2 (Direct
Inventor
Kenjiro Kodama
Masami Morozumi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamasa Shoyu KK
Original Assignee
Yamasa Shoyu KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamasa Shoyu KK filed Critical Yamasa Shoyu KK
Priority to JP7369978A priority Critical patent/JPS552602A/ja
Priority to IT49441/79A priority patent/IT1188839B/it
Priority to US06/049,636 priority patent/US4239905A/en
Priority to FR7915501A priority patent/FR2429020A1/fr
Priority to GB7921146A priority patent/GB2025419B/en
Priority to DE19792924692 priority patent/DE2924692A1/de
Publication of JPS552602A publication Critical patent/JPS552602A/ja
Publication of JPS5726680B2 publication Critical patent/JPS5726680B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP7369978A 1978-06-20 1978-06-20 1-beta-d-arabinofranosylcytosine-5'-phosphoric acid oleyl ester Granted JPS552602A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP7369978A JPS552602A (en) 1978-06-20 1978-06-20 1-beta-d-arabinofranosylcytosine-5'-phosphoric acid oleyl ester
IT49441/79A IT1188839B (it) 1978-06-20 1979-06-18 Derivati di arabino-furanosil-citosina
US06/049,636 US4239905A (en) 1978-06-20 1979-06-18 1-β-D-Arabinofuranosylcytosine-5'-oleyl phosphate and salts thereof
FR7915501A FR2429020A1 (fr) 1978-06-20 1979-06-18 1-b-d-arabinofuranosylcytosine-5'-oleyl phosphate et ses sels, et medicaments contenant ces substances
GB7921146A GB2025419B (en) 1978-06-20 1979-06-18 M 1 d-arabinofuranosylcytosine-5-oleyl phosphate
DE19792924692 DE2924692A1 (de) 1978-06-20 1979-06-19 1- beta -d-arabinofuranosylcytosin- 5'-oleyl-phosphat und dessen salze

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7369978A JPS552602A (en) 1978-06-20 1978-06-20 1-beta-d-arabinofranosylcytosine-5'-phosphoric acid oleyl ester

Publications (2)

Publication Number Publication Date
JPS552602A true JPS552602A (en) 1980-01-10
JPS5726680B2 JPS5726680B2 (Direct) 1982-06-05

Family

ID=13525713

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7369978A Granted JPS552602A (en) 1978-06-20 1978-06-20 1-beta-d-arabinofranosylcytosine-5'-phosphoric acid oleyl ester

Country Status (6)

Country Link
US (1) US4239905A (Direct)
JP (1) JPS552602A (Direct)
DE (1) DE2924692A1 (Direct)
FR (1) FR2429020A1 (Direct)
GB (1) GB2025419B (Direct)
IT (1) IT1188839B (Direct)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58225097A (ja) * 1982-06-23 1983-12-27 Yamasa Shoyu Co Ltd ヌクレオシド５′−アルキルもしくはアルケニルりん酸
JPS5925327A (ja) * 1982-07-31 1984-02-09 Hidematsu Hirai 抗腫瘍性複合体の製造方法

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS552601A (en) * 1978-06-20 1980-01-10 Yamasa Shoyu Co Ltd Anti-tumor agent for non-injection use
US4314999A (en) * 1978-07-31 1982-02-09 Proter S.P.A. N-Acyl derivatives of glucosamine having antitumor chemotherapeutic acitivity
US4816570A (en) * 1982-11-30 1989-03-28 The Board Of Regents Of The University Of Texas System Biologically reversible phosphate and phosphonate protective groups
DE4402492A1 (de) * 1994-01-28 1995-08-03 Boehringer Mannheim Gmbh Verfahren zur Herstellung von unsymmetrischen Phosphorsäurediestern
MX363896B (es) * 2013-03-24 2019-04-05 Biokine Therapeutics Ltd Combinación de un antagonista de cxcr4y y citarabina para el uso en el tratamiento de leucemia mieloide.
AU2016291817A1 (en) 2015-07-16 2018-02-22 Biolinerx Ltd. Compositions and methods for treating cancer
BR112018016924A2 (pt) 2016-02-23 2019-01-02 Biolinerx Ltd método de seleção de regime de tratamento para indivíduo que tem leucemia mieloide aguda (lma), método de maximização de resposta ao tratamento de leucemia mieloide aguda (lma), método de tratamento de lma, antagonista de cxcr4 e agente quimioterápico no tratamento de lma

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5289681A (en) * 1976-01-22 1977-07-27 Yamasa Shoyu Co Ltd Preparation of aracytidine -5# phosphoric acid ester derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3284440A (en) * 1964-06-12 1966-11-08 Merck & Co Inc Phosphate esters of cytosine arabinoide and process for preparing same
JPS535678B2 (Direct) * 1973-05-30 1978-03-01
US4086417A (en) * 1974-10-15 1978-04-25 Asahi Kasei Kogyo Kabushiki Kaisha Cytidine nucleotide derivatives
JPS552601A (en) * 1978-06-20 1980-01-10 Yamasa Shoyu Co Ltd Anti-tumor agent for non-injection use
JP3236058B2 (ja) * 1992-04-14 2001-12-04 富士通テン株式会社 オーディオ再生装置

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5289681A (en) * 1976-01-22 1977-07-27 Yamasa Shoyu Co Ltd Preparation of aracytidine -5# phosphoric acid ester derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58225097A (ja) * 1982-06-23 1983-12-27 Yamasa Shoyu Co Ltd ヌクレオシド５′−アルキルもしくはアルケニルりん酸
JPS5925327A (ja) * 1982-07-31 1984-02-09 Hidematsu Hirai 抗腫瘍性複合体の製造方法

Also Published As

Publication number Publication date
DE2924692A1 (de) 1980-01-17
JPS5726680B2 (Direct) 1982-06-05
DE2924692C2 (Direct) 1990-05-10
IT1188839B (it) 1988-01-28
FR2429020B1 (Direct) 1982-11-05
FR2429020A1 (fr) 1980-01-18
GB2025419B (en) 1982-10-13
GB2025419A (en) 1980-01-23
IT7949441A0 (it) 1979-06-18
US4239905A (en) 1980-12-16

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