JPS5517345A - Aminoalcohol derivative - Google Patents

Aminoalcohol derivative

Info

Publication number
JPS5517345A
JPS5517345A JP9010378A JP9010378A JPS5517345A JP S5517345 A JPS5517345 A JP S5517345A JP 9010378 A JP9010378 A JP 9010378A JP 9010378 A JP9010378 A JP 9010378A JP S5517345 A JPS5517345 A JP S5517345A
Authority
JP
Japan
Prior art keywords
formula
compound
chained
methoxy
straight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9010378A
Other languages
Japanese (ja)
Other versions
JPS6058222B2 (en
Inventor
Yoshio Isoda
Soji Kanao
Yoshifumi Ichikawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daiichi Pharmaceutical Co Ltd
Original Assignee
Daiichi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Pharmaceutical Co Ltd filed Critical Daiichi Pharmaceutical Co Ltd
Priority to JP9010378A priority Critical patent/JPS6058222B2/en
Publication of JPS5517345A publication Critical patent/JPS5517345A/en
Publication of JPS6058222B2 publication Critical patent/JPS6058222B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:Aminoalchol derivatives of formula I (R is H, methoxy; R1 is lower alkyl and others; A is straight-chained or branched alkylene of less than 10 carbon atoms) or their salts.
EXAMPLE: N-Ethyl-N-( 3-hydroxy-2, 2-dimethylpropyl )-6-methoxy-1, 2, 3, 4-tetra- hydro-2-naphthylamine.
USE: Spasmolysant and intermediate of drugs; especially it is useful as an intermediate of a drug showing remarkable spasmolytic actitivity on the lower gastrointestinal tract.
PREPARATION: A compound of formula III (B is a straight-chained or branched alkylene of 8 or less carbon atoms) is made to act on a compound of formula II in the presence of a base as trimethylamine to form a compound of formula IV, which is reduced with lithiumaluminum hydride in an organic solvent as ether to produce title compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
JP9010378A 1978-07-24 1978-07-24 Amino alcohol derivative Expired JPS6058222B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP9010378A JPS6058222B2 (en) 1978-07-24 1978-07-24 Amino alcohol derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9010378A JPS6058222B2 (en) 1978-07-24 1978-07-24 Amino alcohol derivative

Publications (2)

Publication Number Publication Date
JPS5517345A true JPS5517345A (en) 1980-02-06
JPS6058222B2 JPS6058222B2 (en) 1985-12-19

Family

ID=13989173

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9010378A Expired JPS6058222B2 (en) 1978-07-24 1978-07-24 Amino alcohol derivative

Country Status (1)

Country Link
JP (1) JPS6058222B2 (en)

Also Published As

Publication number Publication date
JPS6058222B2 (en) 1985-12-19

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