JPS5459284A - Novel 2-pyridylimidazole derivative - Google Patents

Novel 2-pyridylimidazole derivative

Info

Publication number
JPS5459284A
JPS5459284A JP12499577A JP12499577A JPS5459284A JP S5459284 A JPS5459284 A JP S5459284A JP 12499577 A JP12499577 A JP 12499577A JP 12499577 A JP12499577 A JP 12499577A JP S5459284 A JPS5459284 A JP S5459284A
Authority
JP
Japan
Prior art keywords
novel
imideester
formula
imidazole
low
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12499577A
Other languages
Japanese (ja)
Inventor
Toshio Atami
Yuzo Tarumi
Noboru Yoshida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Priority to JP12499577A priority Critical patent/JPS5459284A/en
Priority to AU39492/78A priority patent/AU507066B1/en
Priority to FR7825487A priority patent/FR2401916A1/en
Priority to CH931278A priority patent/CH636862A5/en
Priority to GB7835686A priority patent/GB2004544B/en
Priority to DK392578A priority patent/DK392578A/en
Priority to NL7809075A priority patent/NL7809075A/en
Priority to BE6046598A priority patent/BE870236A/en
Priority to AT0640778A priority patent/AT367412B/en
Priority to IT69049/78A priority patent/IT1160633B/en
Priority to HU78SU989A priority patent/HU184188B/en
Priority to CA310,576A priority patent/CA1110623A/en
Priority to DE19782838892 priority patent/DE2838892A1/en
Priority to SE7809373A priority patent/SE442865B/en
Priority to US05/940,131 priority patent/US4218457A/en
Publication of JPS5459284A publication Critical patent/JPS5459284A/en
Pending legal-status Critical Current

Links

Landscapes

  • Plural Heterocyclic Compounds (AREA)

Abstract

NEW MATERIAL:Imidazole derivatives of formula I.
EXAMPLE: 2-(2'-pyridyl)-5-hydroxy-1H-imidazole-4-carboxyamide.
USE: Carcinostatic agent: the immunosuppression activity is extremely low and the toxicity is also low.
PREPARATION: The reaction of an imideester of formula II (A is iminoethylene with substituents on carbons) and its salt, preferably hydrochloride, with an aminomalonamide is conducted in an organic solvent such as methanol at 0W100°C to form a compound of formla I. The use of a free imideester is preferred in handling and product yield
COPYRIGHT: (C)1979,JPO&Japio
JP12499577A 1977-09-06 1977-10-17 Novel 2-pyridylimidazole derivative Pending JPS5459284A (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
JP12499577A JPS5459284A (en) 1977-10-17 1977-10-17 Novel 2-pyridylimidazole derivative
AU39492/78A AU507066B1 (en) 1977-09-06 1978-09-01 2-Substituted-5-Hydroxy-1h-Imidazole 4-Carbozamide Derivatives
FR7825487A FR2401916A1 (en) 1977-09-06 1978-09-05 NEW DERIVATIVES OF 5-HYDROXY-1H-IMIDAZOLE-4-CARBOXAMIDE SUBSTITUTED IN POSITION 2, THEIR PRODUCTION PROCESS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM
CH931278A CH636862A5 (en) 1977-09-06 1978-09-05 5-HYDROXY-1H-IMIDAZOLE-4-CARBOXAMIDE DERIVATIVES SUBSTITUTED IN 2-POSITION, THEIR SALTS AND PROCESS FOR THEIR PRODUCTION.
GB7835686A GB2004544B (en) 1977-09-06 1978-09-05 2-substituted 5-hydroxy-1h-imidazole-4-carboxamide derivatives and their preparation and use
DK392578A DK392578A (en) 1977-09-06 1978-09-05 PROCEDURE FOR THE PREPARATION OF 2-SUBSTITUTED 5-HYDROXY-1H-IMIDAZOLE-4-CARBOXAMIDE DERIVATIVES OR PHARMACEUTICAL ACCEPTABLE SALTS THEREOF
NL7809075A NL7809075A (en) 1977-09-06 1978-09-05 NEW 2-SUBSTITUATED 5-HYDROXY-1H-IMIDAZOLE-4-CARBOXAMIDE DERIVATIVES.
BE6046598A BE870236A (en) 1977-09-06 1978-09-05 5-HYDROXY-1H-IMIDAZOLE-4-CARBOXAMIDE DERIVATIVES SUBSTITUTED IN POSITION 2, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING CZ COMPOUNDS
AT0640778A AT367412B (en) 1977-09-06 1978-09-05 METHOD FOR PRODUCING NEW 2-SUBSTITUTED 5-HYDROXY-1H-IMIDAZOLE-4CARBOXAMIDE DERIVATIVES AND THEIR SALTS
IT69049/78A IT1160633B (en) 1977-09-06 1978-09-05 2-SUBSTITUTED DERIVATIVES OF 5-HYDROXY-1H-IMIDAZOL-4-CARBOXAMIDE
HU78SU989A HU184188B (en) 1977-09-06 1978-09-05 Process for the preparation of new 2-substituted-5.hydroxy-1h-imidazol-4-carboxamide derivatives
CA310,576A CA1110623A (en) 1977-09-06 1978-09-05 2-substituted 5-hydroxy-1h-imidazole-4-carboxamide derivatives and their preparation and use
DE19782838892 DE2838892A1 (en) 1977-09-06 1978-09-06 2-SUBSTITUTED-5-HYDROXY-1H-IMIDAZOLE-4-CARBOXAMIDE DERIVATIVES, THE PROCESS FOR THEIR MANUFACTURING AND THE PHARMACEUTICAL PRODUCTS CONTAINING THEM
SE7809373A SE442865B (en) 1977-09-06 1978-09-06 PHARMACEUTICAL ACTIVE 2-SUBSTITUTED-5-HYDROXY-1H-IMIDAZOLE-4-CARBOXAMIDE DERIVATIVES
US05/940,131 US4218457A (en) 1977-09-06 1978-09-06 2-Substituted 5-hydroxy-1H-imidazole-4-carboxamide derivatives and use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12499577A JPS5459284A (en) 1977-10-17 1977-10-17 Novel 2-pyridylimidazole derivative

Publications (1)

Publication Number Publication Date
JPS5459284A true JPS5459284A (en) 1979-05-12

Family

ID=14899281

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12499577A Pending JPS5459284A (en) 1977-09-06 1977-10-17 Novel 2-pyridylimidazole derivative

Country Status (1)

Country Link
JP (1) JPS5459284A (en)

Similar Documents

Publication Publication Date Title
JPS568352A (en) Aminoalkylvenzene derivative
JPS53135972A (en) Synthesis of urea derivative
HUT64318A (en) Process for production benzodpyrane derivativs and pharmaceutical preparations containing these compounds as effective substance
JPS5459284A (en) Novel 2-pyridylimidazole derivative
JPS5671075A (en) Novel imidazole derivative
ES472009A1 (en) Copper complexes of N-pyrazole, N-imidazole and N-triazole acetanilides, their preparation and their use as fungicides.
JPS5259174A (en) Preparation of n-substituted uracil compounds
JPS5528955A (en) Novel glycerophosphoric acid derivative, its salt, their preparation, and carcinostatic agent containing the same.
JPS54100371A (en) Novel imidazole c-nucleoside derivative
JPS5639062A (en) Slufenamide derivative
JPS5651460A (en) Pyrimidine derivative, its preparation, and antitumor agent comprising its derivative
GB1511475A (en) Hydrazinopyridazine derivatives having antihypertensive activity
JPS5616474A (en) 5-fluorouracil derivative
JPS5441874A (en) Novel 2-substituted imidazole derivative
JPS57171989A (en) Aminometyl-secalonic acid and its preparation
JPS5551068A (en) Novel hydantoin derivative, and antiphlogistic analgesic agent containing the same
JPS5714598A (en) 5-substituted-1-beta-d-arabinofuranosyluracil derivative and its preparation
JPS55102567A (en) Nicotinoylpantethine derivative
JPS5527141A (en) Novel 2-pyridyl-imidazole-carboxamide derivative
JPS55147276A (en) Thiophenesulfonylhydrazone and its preparation
JPS5473797A (en) Pyride 3.2.1-jk carbazole derivative
JPS54100384A (en) Novel penicillamine derivative
JPS5549379A (en) Pyriod 3,2,1-ed quinoxaline-6-carboxylic acid derivative
JPS5735589A (en) 5-thienyloxazoline derivative, its preparation and selective herbicide
JPS55102572A (en) 5-fluorouracil derivative and its preparation